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Browsing Center for Genomic Regulation (CRG) by Subject "ADN -- Dany"

Browsing Center for Genomic Regulation (CRG) by Subject "ADN -- Dany"

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  • JARID1B expression and its function in DNA damage repair are tightly regulated by miRNAs in breast cancer
    Mocavini, Ivano; Pippa, Simone; Licursi, Valerio; Paci, Paola; Trisciuoglio, Daniela; Mannironi, Cecilia; Presutti, Carlo; Negri, Rodolfo (Wiley Open Access, 2019)
    JARID1B/KDM5B histone demethylase's mRNA is markedly overexpressed in breast cancer tissues and cell lines and the protein has been shown to have a prominent role in cancer cell proliferation and DNA repair. However, the ...
  • Slow-growing cells within isogenic populations have increased RNA polymerase error rates and DNA damage
    Dijk, David van; Dhar, Riddhiman; Missarova, Alsu, 1990-; Espinar, Lorena; Blevins, William Robert, 1987-; Lehner, Ben, 1978-; Carey, Lucas, 1980- (Nature Publishing Group, 2015)
    Isogenic cells show a large degree of variability in growth rate, even when cultured in the same environment. Such cell-to-cell variability in growth can alter sensitivity to antibiotics, chemotherapy and environmental ...
  • The Aurora-B-dependent NoCut checkpoint prevents damage of anaphase bridges after DNA replication stress
    Amaral, Nuno, 1984-; Vendrell Arasa, Alexandre; Funaya, Charlotta; Idrissi, Fatima-Zahra; Maier, Michael, 1983-; Kumar, Arun; Neurohr, Gabriel Erich; Colomina, Neus; Torres Rosell, Jordi; Geli, María-Isabel; Mendoza, Manuel (Mendoza Palomares) (Nature Publishing Group, 2016)
    Anaphase chromatin bridges can lead to chromosome breakage if not properly resolved before completion of cytokinesis. The NoCut checkpoint, which depends on Aurora B at the spindle midzone, delays abscission in response ...
  • Translational regulation of APOBEC3G mRNA by Vif requires its 5′UTR and contributes to restoring HIV-1 infectivity
    Guerrero, Santiago; Libre, Camille; Batisse, Julien; Mercenne, Gaëlle; Richer, Delphine; Laumond, Géraldine; Decoville, Thomas; Moog, Christiane; Marquet, Roland; Paillart, Jean-Christophe (Nature Research, 2016)
    The essential HIV-1 viral infectivity factor (Vif) allows productive infection of non-permissive cells expressing cytidine deaminases APOBEC3G (A3G) and A3F by decreasing their cellular level, and preventing their incorporation ...

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