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Browsing Center for Genomic Regulation (CRG) by Subject "5-HT"

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The alternative serotonin transporter promoter P2 impacts gene function in females with irritable bowel syndrome

Mohr, Sandra; Bustamante Pineda, Mariona; Estivill, Xavier, 1955-; Niesler, Beate (Wiley, 2021)

Irritable bowel syndrome (IBS) is a gut-brain disorder in which symptoms are shaped by serotonin acting centrally and peripherally. The serotonin transporter gene SLC6A4 has been implicated in IBS pathophysiology, but the ...

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