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Browsing Center for Genomic Regulation (CRG) by Author "Xu, Heping"

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Complement activation contributes to subretinal fibrosis through the induction of epithelial-to-mesenchymal transition (EMT) in retinal pigment epithelial cells

Llorián-Salvador, María; Byrne, Eimear M.; Szczepan, Manon; Little, Karis; Chen, Mei; Xu, Heping (BioMed Central, 2022)

Background: We previously reported higher plasma levels of complement fragments C3a and C5a in neovascular Age-related Macular Degeneration (nAMD) patients with macular fibrosis. This study aimed to understand whether ...

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