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Browsing Center for Genomic Regulation (CRG) by Author "Valenzuela, Alejandro"

Browsing Center for Genomic Regulation (CRG) by Author "Valenzuela, Alejandro"

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  • Barteri, Fabio; Valenzuela, Alejandro; Farré, Xavier; Juan, David; Muntané, Gerard; Esteve Altava, Borja; Navarro i Cuartiellas, Arcadi, 1969- (Oxford University Press, 2023)
    Motivation: Coincidence of Convergent Amino Acid Substitutions (CAAS) with phenotypic convergences allow pinpointing genes and even individual mutations that are likely to be associated with trait variation within their ...
  • Kuderna, Lukas F.K.; Valenzuela, Alejandro; Navarro i Cuartiellas, Arcadi, 1969-; Marquès i Bonet, Tomàs, 1975-; Kai-How Farh, Kyle (Nature Research, 2023)
    Noncoding DNA is central to our understanding of human gene regulation and complex diseases1,2, and measuring the evolutionary sequence constraint can establish the functional relevance of putative regulatory elements in ...
  • Melin, Amanda D.; Orkin, Joseph D.; Valenzuela, Alejandro; Gut, Ivo Glynne; Gut, Marta; Lizano González, Esther, 1974-; Marquès i Bonet, Tomàs, 1975-; Navarro i Cuartiellas, Arcadi, 1969-; Juan, David; Higham, James P. (Wiley, 2021)
    The novel coronavirus SARS-CoV-2, which in humans leads to the disease COVID-19, has caused global disruption and more than 2 million fatalities since it first emerged in late 2019. As we write, infection rates are at their ...

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