Browsing Center for Genomic Regulation (CRG) by Author "Tajes Orduña, Marta"

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Defining quantification methods and optimizing protocols for microarray hybridization of circulating microRNAs

Garcia-Elias Heras, Anna; Alloza, Leonor; Puigdecanet Riubugent, Eulàlia; Nonell Mazelon, Lara, 1972-; Tajes Orduña, Marta; Curado, Joao; Enjuanes Grau, Cristina; Díaz, Oscar; Bruguera-Cortada, Jordi; Martí-Almor, Julio; Comín Colet, Josep; Benito Villabriga, Begoña (Nature Publishing Group, 2017)

MicroRNAs (miRNAs) have emerged as promising biomarkers of disease. Their potential use in clinical practice requires standardized protocols with very low miRNA concentrations, particularly in plasma samples. Here we tested ...
Methylglyoxal produced by amyloid-β peptide-induced nitrotyrosination of triosephosphate isomerase triggers neuronal death in Alzheimer's disease

Tajes Orduña, Marta; Eraso Pichot, Abel; Rubio Moscardó, Fanny; Guivernau Almazán, Biuse, 1988-; Ramos Fernández, Eva, 1984-; Bosch Morató, Mònica, 1986-; Guix Ràfols, Francesc Xavier; Clarimón Echevarría, Jordi; Miscione, Gian Pietro; Boada, Mercè; Gil Gómez, Gabriel; Suzuki, Toshiharu; Molina, Henrik; Villà i Freixa, Jordi; Vicente García, Rubén, 1978-; Muñoz López, Francisco José, 1964- (IOS Press, 2014)

Amyloid-β peptide (Aβ) aggregates induce nitro-oxidative stress, contributing to the characteristic neurodegeneration found in Alzheimer's disease (AD). One of the most strongly nitrotyrosinated proteins in AD is the ...

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