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Browsing Center for Genomic Regulation (CRG) by Author "Stroustrup, Nicholas"

Browsing Center for Genomic Regulation (CRG) by Author "Stroustrup, Nicholas"

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  • Oswal, Natasha; Martin, Olivier M. F., 1991-; Stroustrup, Sofia; Bruckner, Monika Anna Matusiak; Stroustrup, Nicholas (Public Library of Science (PLoS), 2022)
    Aging involves a transition from youthful vigor to geriatric infirmity and death. Individuals who remain vigorous longer tend to live longer, and within isogenic populations of C. elegans the timing of age-associated ...
  • Schiffer, Jodie A.; Servello, Francesco A.; Heath, William R.; Amrit, Francis Raj Ghandi; Stumbur, Stephanie V; Eder, Matthias; Martin, Olivier M. F.; Johnsen, Sean B.; Stanley, Julia A.; Tam, Hannah; Brennan, Sara J.; McGowan, Natalie G.; Vogelaar, Abigail L.; Xu, Yuyan; Serkin, William T.; Ghazi, Arjumand; Stroustrup, Nicholas; Apfeld, Javier (eLife, 2020)
    Hydrogen peroxide is the preeminent chemical weapon that organisms use for combat. Individual cells rely on conserved defenses to prevent and repair peroxide-induced damage, but whether similar defenses might be coordinated ...
  • Lin, Xin-Xuan; Sen, Ilke; Janssens, Georges E.; Zhou, Xin; Fonslow, Bryan R.; Edgar, Daniel; Stroustrup, Nicholas; Swoboda, Peter; Yates, John R.; Ruvkun, Gary; Riedel, Christian G. (Nature Research, 2018)
    The ability to perceive and respond to harmful conditions is crucial for the survival of any organism. The transcription factor DAF-16/FOXO is central to these responses, relaying distress signals into the expression of ...
  • Stroustrup, Nicholas (Elsevier, 2018)
    Many dietary, pharmaceutical, and genetic interventions have been found to increase the lifespan of laboratory animals. Several are now being explored for clinical application. To understand the physiologic action and ...
  • Servello, Francesco A.; Fernandes, Rute; Eder, Matthias; Harris, Nathan; Martin, Olivier M. F., 1991-; Oswal, Natasha; Lindberg, Anders; Derosiers, Nohelly; Sengupta, Piali; Stroustrup, Nicholas; Apfeld, Javier (eLife, 2022)
    Hydrogen peroxide is the most common reactive chemical that organisms face on the microbial battlefield. The rate with which hydrogen peroxide damages biomolecules required for life increases with temperature, yet little ...
  • Cutler, Kevin J.; Stringer, Carsen; Lo, Teresa W.; Rappez, Luca; Stroustrup, Nicholas; Peterson, S. Brook; Wiggins, Paul A.; Mougous, Joseph D. (Nature Research, 2022)
    Advances in microscopy hold great promise for allowing quantitative and precise measurement of morphological and molecular phenomena at the single-cell level in bacteria; however, the potential of this approach is ultimately ...
  • Janssens, Georges E.; Lin, Xin-Xuan; Millán Ariño, Lluís, 1984-; Kavšek, Alan; Sen, Ilke; Seinstra, Renée I.; Stroustrup, Nicholas; Nollen, Ellen A. A.; Riedel, Christian G. (Elsevier, 2019)
    Aging strongly influences human morbidity and mortality. Thus, aging-preventive compounds could greatly improve our health and lifespan. Here we screened for such compounds, known as geroprotectors, employing the power of ...

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