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Browsing Center for Genomic Regulation (CRG) by Author "Rinaldi, Lorenzo, 1986-"

Browsing Center for Genomic Regulation (CRG) by Author "Rinaldi, Lorenzo, 1986-"

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  • Rinaldi, Lorenzo, 1986-; Datta, Debayan; Serrat, Judit; Morey Ramonell, Lluís; Solanas, Guiomar; Avgustinova, Alexandra; Blanco, Enrique; Pons, José Ignacio; Matallanas, David; Kriegsheim, Alex von; Di Croce, Luciano; Aznar Benitah, Salvador (Elsevier, 2016)
    The genome-wide localization and function of endogenous Dnmt3a and Dnmt3b in adult stem cells are unknown. Here, we show that in human epidermal stem cells, the two proteins bind in a histone H3K36me3-dependent manner to ...
  • Rinaldi, Lorenzo, 1986-; Avgustinova, Alexandra; Martín, Mercè; Datta, Debayan; Solanas, Guiomar; Prats, Neus; Aznar Benitah, Salvador (eLife, 2017)
    The DNA methyltransferase Dnmt3a suppresses tumorigenesis in models of leukemia and lung cancer. Conversely, deregulation of Dnmt3b is thought to generally promote tumorigenesis. However, the role of Dnmt3a and Dnmt3b in ...

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