Browsing Center for Genomic Regulation (CRG) by Author "Fabregat, Isabel"

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NADPH oxidase 4 (Nox4) deletion accelerates liver regeneration in mice

Herranz-Itúrbe, Macarena; López-Luque, Judit; Gonzalez-Sanchez, Ester; Caballero-Díaz, Daniel; Crosas-Molist, Eva; Martín-Mur, Beatriz; Gut, Marta; Esteve-Codina, Anna; Jaquet, Vincent; Jiang, Joy X.; Török, Natalie J.; Fabregat, Isabel (Elsevier, 2021)

Liver is a unique organ in displaying a reparative and regenerative response after acute/chronic damage or partial hepatectomy, when all the cell types must proliferate to re-establish the liver mass. The NADPH oxidase ...
The hepatocyte epidermal growth factor receptor (EGFR) pathway regulates the cellular interactome within the liver fibrotic niche

Gonzalez-Sanchez, Ester; Vaquero, Javier; Caballero Díaz, Daniel; Grzelak, Jan; Fusté, Noel P.; Bertran, Esther; Amengual, Josep; García Sáez, Juan; Martín-Mur, Beatriz; Gut, Marta; Esteve-Codina, Anna; Alay, Ania; Coulouarn, Cedric; Calero Pérez, Silvia; Valdecantos, Pilar; Valverde, Angela M.; Sánchez, Aránzazu; Herrera, Blanca; Fabregat, Isabel (Wiley, 2024)

Liver fibrosis is the consequence of chronic liver injury in the presence of an inflammatory component. Although the main executors of this activation are known, the mechanisms that lead to the inflammatory process that ...

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