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Browsing Center for Genomic Regulation (CRG) by Author "Gabaldón Estevan, Juan Antonio, 1973-"

Browsing Center for Genomic Regulation (CRG) by Author "Gabaldón Estevan, Juan Antonio, 1973-"

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  • Jiménez Guri, Eva; Huerta Cepas, Jaime; Cozzuto, Luca; Wotton, Karl R.; Kang, Hui; Himmelbauer, Heinz; Roma, Guglielmo; Gabaldón Estevan, Juan Antonio, 1973-; Jaeger, Johannes, 1973- (BioMed Central, 2013)
    BACKGROUND: Modern sequencing technologies have massively increased the amount of data available for comparative genomics. Whole-transcriptome shotgun sequencing (RNA-seq) provides a powerful basis for comparative studies. ...
  • Morales, Lucia; Noel, Benjamin; Porcel, Betina; Marcet Houben, Marina; Hullo, Marie-Françoise; Sacerdot, Christine; Tekaia, Fredj; Leh-Louis, Véronique; Despons, Laurence; Khanna, Varun; Aury, Jean-Marc; Barbe, Valérie; Coloux, Arnaud; Labadie, Karine; Pelletier, Eric; Souciet, Jean-Luc; Boekhout, Teun; Gabaldón Estevan, Juan Antonio, 1973-; Wincker, Patrick; Dujon, Bernard (Oxford University Press, 2013)
    The numerous yeast genome sequences presently available provide a rich source of information for functional as well as evolutionary genomics but unequally cover the large phylogenetic diversity of extant yeasts. We present ...
  • Kunze, Gotthard; Gabaldón Estevan, Juan Antonio, 1973-; Marcet Houben, Marina; Neuvéglise, Cécile (BioMed Central, 2014)
    Background: The industrially important yeast Blastobotrys (Arxula) adeninivorans is an asexual hemiascomycete phylogenetically very distant from Saccharomyces cerevisiae. Its unusual metabolic flexibility allows it to use ...
  • Julca, Irene; Droby, Samir; Sela, Noa; Marcet Houben, Marina; Gabaldón Estevan, Juan Antonio, 1973- (Oxford University Press, 2015)
    Penicillium digitatum and Penicillium expansum are two closely related fungal plant pathogens causing green and blue mold in harvested fruit, respectively. The two species differ in their host specificity, being P. digitatum ...
  • Vandewege, Michael W.; Mangum, Sarah F.; Gabaldón Estevan, Juan Antonio, 1973-; Castoe, Todd A.; Ray, David A.; Hoffmann, Federico G. (Oxford University Press, 2016)
    Olfactory receptors (ORs) are membrane proteins that mediate the detection of odorants in the environment, and are the largest vertebrate gene family. Comparative studies of mammalian genomes indicate that OR repertoires ...
  • Hovhannisyan, Hrant, 1992-; Hafez Khafaga, Ahmed Ibrahem, 1987-; Llorens, Carlos, 1968-; Gabaldón Estevan, Juan Antonio, 1973- (Oxford University Press, 2020)
    MOTIVATION: Numerous sequencing studies, including transcriptomics of host-pathogen systems, sequencing of hybrid genomes, xenografts, mixed species systems, metagenomics and meta-transcriptomics, involve samples containing ...
  • Morel, Guillaume; Sterck, Lieven; Swennen, Dominique; Marcet Houben, Marina; Onesime, Djamila; Levasseur, Anthony; Jacques, Noémie; Mallet, Sandrine; Couloux, Arnaud; Labadie, Karine; Amselem, Joëlle; Beckerich, Jean-Marie; Henrissat, Bernard; van de Peer, Yves; Wincker, Patrick; Souciet, Jean-Luc; Gabaldón Estevan, Juan Antonio, 1973-; Tinsley, Colin R.; Casaregola, Serge (Nature Publishing Group, 2015)
    The evolutionary history of the characters underlying the adaptation of microorganisms to food and biotechnological uses is poorly understood. We undertook comparative genomics to investigate evolutionary relationships of ...
  • Pittis, Alexandros, 1982-; Goh, Valerie; Cebrián Serrano, Alberto; Wettmarshausen, Jennifer; Perocchi, Fabiana; Gabaldón Estevan, Juan Antonio, 1973- (Nature Research, 2020)
    Calcium (Ca2+) influx into mitochondria occurs through a Ca2+-selective uniporter channel, which regulates essential cellular processes in eukaryotic organisms. Previous evolutionary analyses of its pore-forming subunits ...
  • Masgrau Fortuny, Aina, 1986-; Battola, Andrea, 1987-; Sanmartín Olmo, Trinidad; Pryszcz, Leszek Piotr, 1985-; Gabaldón Estevan, Juan Antonio, 1973-; Mendoza, Manuel (Mendoza Palomares) (American Society for Cell Biology, 2017)
    Boi1 and Boi2 (Boi1/2) are budding yeast plasma membrane proteins that function in polarized growth, and in cytokinesis inhibition in response to chromosome bridges via the NoCut abscission checkpoint. How Boi1/2 act in ...
  • Papp, Csaba; Kocsis, Katica; Tóth, Renáta; Bodai, László; Willis, Jesse R.; Ksiezopolska, Ewa; Lozoya-Pérez, Nancy E.; Vágvölgyi, Csaba; Mora Montes, Hector; Gabaldón Estevan, Juan Antonio, 1973-; Nosanchuk, Joshua D.; Gácser, Attila (American Society for Microbiology, 2018)
    Candida species are a major cause of life-threatening bloodstream infections worldwide. Although Candida albicans is responsible for the vast majority of infections, the clinical relevance of other Candida species has also ...
  • Powell, Sean; Forslund, Kristoffer; Szklarczyk, Damian; Trachana, Kalliopi; Roth, Alexander; Huerta Cepas, Jaime; Gabaldón Estevan, Juan Antonio, 1973-; Rattei, Thomas; Creevey, Chris; Kuhn, Michael; Jensen, Lars J.; Mering, Christian von; Bork, Peer (Oxford University Press, 2014)
    With the increasing availability of various 'omics data, high-quality orthology assignment is crucial for evolutionary and functional genomics studies. We here present the fourth version of the eggNOG database (available ...
  • Chakraborty, Tanmoy; Thuer, Ernst, 1986-; Heijink, Marieke; Tóth, Renáta; Bodai, László; Vágvölgyi, Csaba; Giera, Martin; Gabaldón Estevan, Juan Antonio, 1973-; Gácser, Attila (Taylor & Francis, 2018)
    Lipid mediators, derived from arachidonic acid metabolism, play an important role in immune regulation. The functions of bioactive eicosanoids range from modulating cytokine signaling and inflammasome formation to ...
  • Cillingová, Andrea; Zeman, Igor; Tóth, Renáta; Neboháčová, Martina; Dunčková, Ivana; Hölcová, Mária; Jakúbková, Michaela; Gérecová, Gabriela; Pryszcz, Leszek Piotr, 1985-; Tomáška, L'ubomír; Gabaldón Estevan, Juan Antonio, 1973-; Gácser, Attila; Nosek, Jozef (Nature Publishing Group, 2017)
    Several yeast species catabolize hydroxyderivatives of benzoic acid. However, the nature of carriers responsible for transport of these compounds across the plasma membrane is currently unknown. In this study, we analyzed ...
  • Marcet Houben, Marina; Gabaldón Estevan, Juan Antonio, 1973- (Oxford University Press, 2020)
    MOTIVATION: The evolution and role of gene clusters in eukaryotes is poorly understood. Currently, most studies and computational prediction programs limit their focus to specific types of clusters, such as those involved ...
  • Mariotti, Marco, 1984-; Santesmasses Ruiz, Didac, 1978-; Capella Gutiérrez, Salvador Jesús, 1985-; Mateo, Andrea; Arnan Ros, Carme; Johnson, Rory; D’Aniello, Salvatore; Yim, Sun Hee; Gladyshev, Vadim N.; Serras Rigalt, Florenci; Corominas Guiu, Montserrat; Gabaldón Estevan, Juan Antonio, 1973-; Guigó Serra, Roderic (Cold Spring Harbor Laboratory Press, 2015)
    Selenoproteins are proteins that incorporate selenocysteine (Sec), a nonstandard amino acid encoded by UGA, normally a stop codon. Sec synthesis requires the enzyme Selenophosphate synthetase (SPS or SelD), conserved in ...
  • Marcet Houben, Marina; Gabaldón Estevan, Juan Antonio, 1973- (Nature Research, 2019)
    Gene clusters comprise genomically co-localized and potentially co-regulated genes that tend to be conserved across species. In eukaryotes, multiple examples of metabolic gene clusters are known, particularly among fungi ...
  • Ksiezopolska, Ewa; Gabaldón Estevan, Juan Antonio, 1973- (MDPI, 2018)
    Fungal infections, such as candidiasis caused by Candida, pose a problem of growing medical concern. In developed countries, the incidence of Candida infections is increasing due to the higher survival of susceptible ...
  • Gabaldón Estevan, Juan Antonio, 1973-; Naranjo Ortiz, Miguel Ángel, 1989-; Marcet Houben, Marina (Oxford University Press, 2016)
    Saccharomycotina comprises a diverse group of yeasts that includes numerous species of industrial or clinical relevance. Opportunistic pathogens within this clade are often assigned to the genus Candida but belong to ...
  • Abascal, Federico; Corvelo, André; Cruz, Fernando; Villanueva Cañas, José Luis, 1984-; Vlasova, Anna; Marcet Houben, Marina; Prieto Barja, Pablo, 1986-; Quilez Oliete, Javier; Frias, Leonor; Ribeca, Paolo; Capella Gutiérrez, Salvador Jesús, 1985-; Câmara Ferreira, Francisco; Lowy Gallego, Ernesto; Cozzuto, Luca; Erb, Ionas; Rodríguez Ales, José Luis; Ruiz Orera, Jorge, 1988-; Reverter, Ferran; Derdak, Sophia; Blanc, Julie; Gut, Marta; Lorente-Galdós, Belén, 1981-; Gut, Ivo Glynne; Guigó Serra, Roderic; Gabaldón Estevan, Juan Antonio, 1973-; Godoy, José A. (BioMed Central, 2016)
    Background: Genomic studies of endangered species provide insights into their evolution and demographic history, reveal patterns of genomic erosion that might limit their viability, and offer tools for their effective ...
  • Chipman, Ariel D; Capella Gutiérrez, Salvador Jesús, 1985-; Gabaldón Estevan, Juan Antonio, 1973-; Guigó Serra, Roderic; Mariotti, Marco, 1984-; Richards, Stephan (Public Library of Science (PLoS), 2014)
    Myriapods (e.g., centipedes and millipedes) display a simple homonomous body plan relative to other arthropods. All members of the class are terrestrial, but they attained terrestriality independently of insects. Myriapoda ...

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