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Cannabinoid addiction: behavioral models and neural correlates

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dc.contributor.author Maldonado, Rafael, 1961-
dc.contributor.author Rodríguez de Fonseca, Fernando
dc.date.accessioned 2012-07-05T06:53:55Z
dc.date.available 2012-07-05T06:53:55Z
dc.date.issued 2002
dc.identifier.citation Maldonado R, Rodríguez-Fonseca F. Cannabinoid addiction: behavioral models and neural correlates. J. Neurosci. 2002; 22(9): 3326-31. DOI: 10.1523/JNEUROSCI.22-09-03326.2002
dc.identifier.issn 0270-6474
dc.identifier.uri http://hdl.handle.net/10230/16665
dc.description.abstract The use of cannabis sativa preparations as recreational drugs can be traced back to the earliest civilizations. However, animal models of cannabinoid addiction allowing the exploration of neural correlates of cannabinoid abuse have been developed only recently. We review these models and the role of the CB1 cannabinoid receptor, the main target of natural cannabinoids, and its interaction with opioid and dopamine transmission in reward circuits. Extensive reviews on the molecular basis of cannabinoid action are available elsewhere (Piomelli et al., 2000;Schlicker and Kathmann, 2001).
dc.description.sponsorship This work has been supported by grants from Plan Nacional Sobre Drogas, European Communities BIOM ED2 Grant PL 982267 and Fifth Framework Programme, Grant QLRT-2000-01691, Generalitat de Catalunya (Research Distinction), Human Frontier Science Program Organization (RG0077/2000-B), Ministerio de Ciencia y Tecnología (SAF 2000-0101), Fondo de Investigación Sanitaria (FIS 2001-00654), and Laboratorios Dr. Esteve.
dc.format.mimetype application/pdf
dc.language.iso eng
dc.publisher Society for Neuroscience
dc.relation.ispartof J. Neurosci. 2002; 22(9): 3326-31
dc.rights (c) 2002, Society for Neuroscience. The published version is available at: http://www.jneurosci.org/content/22/9/3326
dc.subject.other Cannabinoides -- Efectes fisiològics
dc.subject.other Cannabinoides -- Receptors
dc.subject.other Drogoaddicció -- Aspectes moleculars
dc.title Cannabinoid addiction: behavioral models and neural correlates
dc.type info:eu-repo/semantics/article
dc.identifier.doi http://dx.doi.org/10.1523/JNEUROSCI.22-09-03326.2002
dc.rights.accessRights info:eu-repo/semantics/openAccess
dc.type.version info:eu-repo/semantics/publishedVersion

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