Identifying protein-coding genes in genomic sequences

Harrow, Jennifer; Nagy, Alinda; Reymond, Alexandre; Alioto, Tyler; Patthy, Laszlo; Antonarakis, Stylianos E.; Guigó Serra, Roderic

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dc.contributor.author	Harrow, Jennifer
dc.contributor.author	Nagy, Alinda
dc.contributor.author	Reymond, Alexandre
dc.contributor.author	Alioto, Tyler
dc.contributor.author	Patthy, Laszlo
dc.contributor.author	Antonarakis, Stylianos E.
dc.contributor.author	Guigó Serra, Roderic
dc.date.accessioned	2011-11-28T11:08:09Z
dc.date.available	2011-11-28T11:08:09Z
dc.date.issued	2009
dc.identifier.citation	Harrow J, Nagy A, Reymond A, Alioto T, Patthy L, Antonarakis S E, Guigó R. Identifying protein-coding genes in genomic sequences. Genome Biology. 2009;10:201. DOI: 10.1186/gb-2009-10-1-201
dc.identifier.issn	1465-6906
dc.identifier.uri	http://hdl.handle.net/10230/13151
dc.description.abstract	The vast majority of the biology of a newly sequenced genome is inferred from the set of encoded proteins. Predicting this set is therefore invariably the first step after the completion of the genome DNA sequence. Here we review the main computational pipelines used to generate the human reference protein-coding gene sets.
dc.description.sponsorship	This work was carried out as part of the BioSapiens project. The BioSapiens project is funded by the European Commission within its FP6 Programme, under the thematic area "Life sciences, genomics and biotechnology for health", contract number LHSG-CT-2003-503265. AR, SA and RG also acknowledge support from grants U01HG003150 and U01HG003147 from the National Human Genome Research Institute, NIH. RG acknowledges support from grant BIO2006-03380 from the Spanish Ministry of Education and Science. AR and SA acknowledge support from the EU AnEUploidy project, and the NCCR Frontiers in Genetics. LP thanks the Hungarian National Office for Research and Technology for partial support under grant no. RET14/2005. JA's work is supported by the Wellcome Trust.
dc.format.mimetype	application/pdf
dc.language.iso	eng
dc.publisher	BioMed Central
dc.relation.ispartof	Genome Biology. 2009;10:201
dc.rights	© 2009 BioMed Central Ltd./nThe electronic version of this article is the complete one and can be found online at http://genomebiology.com/2009/10/1/201
dc.subject.other	Biologia computacional -- Mètodes
dc.subject.other	Seqüència de nucleòtids
dc.title	Identifying protein-coding genes in genomic sequences
dc.type	info:eu-repo/semantics/article
dc.identifier.doi	http://dx.doi.org/10.1186/gb-2009-10-1-201
dc.subject.keyword	Animals
dc.subject.keyword	Humans
dc.subject.keyword	Proteins
dc.subject.keyword	Genes
dc.subject.keyword	Genome
dc.relation.projectID	info:eu-repo/grantAgreement/EC/FP6/503265
dc.relation.projectID	info:eu-repo/grantAgreement/ES/2PN/BIO2006-03380
dc.rights.accessRights	info:eu-repo/semantics/openAccess
dc.type.version	info:eu-repo/semantics/publishedVersion