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dc.contributor.author | Castellano Hereza, Sergi |
dc.contributor.author | Gladyshev, Vadim N. |
dc.contributor.author | Guigó Serra, Roderic |
dc.contributor.author | Berry, Marla J. |
dc.date.accessioned | 2011-11-28T11:08:03Z |
dc.date.available | 2011-11-28T11:08:03Z |
dc.date.issued | 2008 |
dc.identifier.citation | Castellano S, Gladyshev V N, Guigó R, Berry M J. SelenoDB 1.0 : a database of selenoprotein genes, proteins and SECIS elements. Nucleic acids research. 2008; 36 supl 1: D332-D338. DOI: 10.1093/nar/gkm731 |
dc.identifier.issn | 0305-1048 |
dc.identifier.uri | http://hdl.handle.net/10230/13147 |
dc.description.abstract | Selenoproteins are a diverse group of proteins/nusually misidentified and misannotated in sequence/ndatabases. The presence of an in-frame UGA (stop)/ncodon in the coding sequence of selenoprotein/ngenes precludes their identification and correct/nannotation. The in-frame UGA codons are recoded/nto cotranslationally incorporate selenocysteine,/na rare selenium-containing amino acid. The development/nof ad hoc experimental and, more recently,/ncomputational approaches have allowed the efficient/nidentification and characterization of the/nselenoproteomes of a growing number of species./nToday, dozens of selenoprotein families have been/ndescribed and more are being discovered in recently/nsequenced species, but the correct genomic annotation/nis not available for the majority of these/ngenes. SelenoDB is a long-term project that aims to/nprovide, through the collaborative effort of experimental/nand computational researchers, automatic/nand manually curated annotations of selenoprotein/ngenes, proteins and SECIS elements. Version 1.0 of/nthe database includes an initial set of eukaryotic/ngenomic annotations, with special emphasis on the/nhuman selenoproteome, for immediate inspection/nby selenium researchers or incorporation into more/ngeneral databases. SelenoDB is freely available at/nhttp://www.selenodb.org. |
dc.format.mimetype | application/pdf |
dc.language.iso | eng |
dc.publisher | Oxford University Press |
dc.relation.ispartof | Nucleic Acids Research. 2008;36 supl 1:D332-8 |
dc.rights | © 2007 The Author(s). This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.0/uk/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. Published article is also available at http://nar.oxfordjournals.org/content/36/suppl_1/D332. |
dc.rights.uri | http://creativecommons.org/licenses/by-nc/2.0/uk/ |
dc.subject.other | Biologia molecular |
dc.subject.other | Bioinformàtica |
dc.subject.other | Genòmica -- Bases de dades |
dc.subject.other | Genòmica -- Informàtica |
dc.title | SelenoDB 1.0 : a database of selenoprotein genes, proteins and SECIS elements |
dc.type | info:eu-repo/semantics/article |
dc.identifier.doi | http://dx.doi.org/10.1093/nar/gkm731 |
dc.subject.keyword | 3'UTR |
dc.subject.keyword | Protein databases |
dc.subject.keyword | Genomics |
dc.subject.keyword | Humans |
dc.subject.keyword | Internet |
dc.subject.keyword | Selenoproteins |
dc.subject.keyword | Protein Sequence Analysis |
dc.subject.keyword | RNA Sequence Analysis |
dc.subject.keyword | User-Computer Interface |
dc.rights.accessRights | info:eu-repo/semantics/openAccess |
dc.type.version | info:eu-repo/semantics/publishedVersion |