Visualitza per autor "Tilgner, Hagen, 1980-"

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  • Tilgner, Hagen, 1980-; Knowles, David G.; Johnson, Rory; Davis, Carrie A.; Chakrabortty, Sudipto; Djebali, Sarah; Curado, Joao; Snyder, Michael; Gingeras, Thomas R.; Guigó Serra, Roderic (Cold Spring Harbor Laboratory Press (CSHL Press), 2012)
    Splicing remains an incompletely understood process. Recent findings suggest that chromatin structure participates in its regulation. Here, we analyze the RNA from subcellular fractions obtained through RNA-seq in the cell ...
  • Curado, Joao; Iannone, Camilla, 1984-; Tilgner, Hagen, 1980-; Valcárcel, J. (Juan); Guigó Serra, Roderic (BioMed Central, 2016)
    After the publication of this work [1] an error was noticed in Fig. 7. The panel‘h’ is missing from Fig. 7. Please see the corrected figure below. The publisher apologises for this error.
  • Tilgner, Hagen, 1980-; Guigó Serra, Roderic (Taylor & Francis (Routledge), 2010)
    RNA plays a central role in the determination of the phenotype of the cell. The molecular mechanisms involved in primary RNA synthesis and subsequent post-processing are not completely understood, but there is increasing ...
  • Maxwell, Christopher A.; Guigó Serra, Roderic; Curado, Joao; Tilgner, Hagen, 1980-; Pujana, Miguel Angel (Public Library of Science (PLoS), 2011)
    Differentiated mammary epithelium shows apicobasal polarity, and loss of tissue organization is an early hallmark of breast carcinogenesis. In BRCA1 mutation carriers, accumulation of stem and progenitor cells in normal ...
  • Djebali, Sarah; Merkel, Angelika; Tanzer, Andrea; Lagarde, Julien; Röder, Maik; Curado, Joao; Derrien, Thomas; Ferreira, Pedro G.; González, David; Johnson, Rory; Kingswood, Colin; Ribeca, Paolo; Sammeth, Michael; Skancke, Jorgen; Tilgner, Hagen, 1980-; Guigó Serra, Roderic; Gingeras, Thomas R. (Nature Publishing Group, 2012)
    Eukaryotic cells make many types of primary and processed RNAs that are found either in specific subcellular compartments or throughout the cells. A complete catalogue of these RNAs is not yet available and their characteristic ...
  • Tilgner, Hagen, 1980- (Universitat Pompeu Fabra, 2011-06-02)
    L’Splicing de les molècules d’ARN és el procés pel qual les seqüències interposades(“introns”) s’eliminen, i les seqüències restants es concatenenper a formar l’ARN madur. La investigació recent mostra que gairebé totsels ...
  • Curado, Joao; Iannone, Camilla, 1984-; Tilgner, Hagen, 1980-; Valcárcel, J. (Juan); Guigó Serra, Roderic (BioMed Central, 2015)
    Background. Pre-mRNA splicing occurs mainly co-transcriptionally, and both nucleosome density and histone modifications have been proposed to play a role in splice site recognition and regulation. However, the extent and ...
  • Tejedor Vaquero, Juan Ramón, 1984-; Tilgner, Hagen, 1980-; Iannone, Camilla, 1984-; Guigó Serra, Roderic; Valcárcel, J. (Juan) (Cambridge University Press, 2015)
    The OLR1 gene encodes the oxidized low-density lipoprotein receptor (LOX-1), which is responsible for the cellular uptake of oxidized LDL (Ox-LDL), foam cell formation in atheroma plaques and atherosclerotic plaque rupture. ...
  • Derrien, Thomas; Johnson, Rory; Bussotti, Giovanni, 1983-; Tanzer, Andrea; Djebali, Sarah; Tilgner, Hagen, 1980-; Guernec, Gregory; Martin, David; Merkel, Angelika; Knowles, David G.; Lagarde, Julien; Veeravalli, Lavanya; Ruan, Xiaoan; Ruan, Yijun; Lassmann, Timo; Carninci, Piero; Brown, James B.; Lipovich, Leonard; González, José M.; Thomas, Mark; Davis, Carrie A.; Shiekhattar, Ramin; Gingeras, Thomas R.; Hubbard, Tim J.; Notredame, Cedric; Harrow, Jennifer; Guigó Serra, Roderic (Cold Spring Harbor Laboratory Press (CSHL Press), 2012)
    The human genome contains many thousands of long noncoding RNAs (lncRNAs). While several studies have demonstrated compelling biological and disease roles for individual examples, analytical and experimental approaches to ...