Visualitza per matèria "Saccharomyces cerevisiae"

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  • Meyer, Markus (Universitat Pompeu Fabra, 2010-03-26)
    The informational content of 3' splice sites is low and the mechanisms whereby they are selected are not clear. Here we enunciate a set of rules that govern their selection. For many introns, secondary structures are a key ...
  • Verschueren, Erik; Spiess, Matthias; Gkourtsa, Areti; Avula, Teja; Landgraf, Christiane; Tapia Mancilla, Victor; Huber, Aline; Volkmer, Rudolf; Winsor, Barbara; Serrano Pubull, Luis, 1982-; Hochstenbach, Frans; Distel, Ben (Public Library of Science (PLoS), 2015)
    To explore the conservation of Src homology 3 (SH3) domain-mediated networks in evolution, we compared the specificity landscape of these domains among four yeast species, Saccharomyces cerevisiae, Ashbya gossypii, Candida ...
  • Llobet Reixach, Laura (2014)
    The genetic bases of complex traits are a challenging matter of study, given the/ncomplexity of the underlying regulation. High-throughput technologies enable collecting/ndata about cellular traits, such as gene expression, ...
  • Huffman, Tori; Link, Kathryn; Nardini, John; Poag, Laura; Flores, Kevin; Banks, H.T.; Blasco, Bernat; Jungfleisch, Jennifer, 1986-; Díez Antón, Juana, 1962- (Academic Publications, 2014)
    Positive-strand RNA viruses, such as the brome mosaic virus (BMV) and hepatitis C virus, utilize a replication cycle which involves the recruitment of RNA genomes from the cellular translation machinery to the viral ...
  • Schneider, Konstantin; Krömer, Jens Olaf; Wittmann, Christoph; Alves-Rodrigues, Isabel; Meyerhans, Andreas; Díez Antón, Juana, 1962-; Heinzle, Elmar (BioMed Central, 2009)
    Background The cellular proteins Pat1p, Lsm1p, and Dhh1p are required for the replication of some positive-strand viruses and therefore are potential targets for new antiviral drugs. To prioritize host targets for antiviral ...
  • Rest, Joshua S.; Morales, Christopher M.; Waldron, John B.; Opulente, Dana A.; Fisher, Julius; Moon, Seungjae; Bullaughey, Kevin; Carey, Lucas; Dedousis, Demitri (University of Chicago Press, 2013)
    Levels of gene expression show considerable variation in eukaryotes, but no fine-scale maps have been made of the fitness consequences of such variation in controlled genetic backgrounds and environments. To address this, ...
  • Plass Pórtulas, Mireya, 1982-; Codony Servat, Carles; Ferreira, Pedro G.; Vilardell, Josep; Eyras Jiménez, Eduardo (Cold Spring Harbor Laboratory Press (CSHL Press) -- RNA, 2012)
    Alternative splicing is the mechanism by which different combinations of exons in the pre-mRNA give rise to distinct mature mRNAs. This process is mediated by splicing factors that bind the pre-mRNA and affect the recognition ...
  • Vendrell Arasa, Alexandre (Universitat Pompeu Fabra, 2009-01-16)
    L'activació sostinguda de Hog1 porta a una inhibició del creixement cel·lular. En aquest treball, hem observat que el fenotip de letalitat causat per l'activació sostinguda de Hog1 és parcialment inhibida per la mutació ...
  • Nikolaou, Christoforos; Althammer, Sonja Daniela; Beato, Miguel; Guigó Serra, Roderic (BioMed Central, 2010)
    BACKGROUND: Recent advances in the field of high-throughput genomics have rendered possible the performance of genome-scale studies to define the nucleosomal landscapes of eukaryote genomes. Such analyses are aimed towards ...
  • Masgrau Fortuny, Aina, 1986- (Universitat Pompeu Fabra, 2014-09-05)
    Cell growth and division requires delivery of new membrane and remodelling factors to the cell surface. In budding yeast, this involves actin-dependent transport of secretory vesicles to sites of growth, followed by vesicle ...
  • Warringer, Jonas; Hult, Malin; Regot Rodríguez de Mier, Sergi; Posas Garriga, Francesc; Sunnerhagen, Per (American Society for Cell Biology, 2010)
    Cellular responses to environmental changes occur on different levels. We investigated the translational response of yeast cells after mild hyperosmotic shock by isolating mRNA associated with multiple ribosomes (polysomes) ...
  • Nikolaou, Christoforos; Bermúdez, Ignacio; Manichanh, Chaysavanh; García Martínez, José; Guigó Serra, Roderic; Pérez Ortín, José E.; Roca, Joaquim (Oxford University Press, 2013)
    Eukaryotic topoisomerase II (topo II) is the essential decatenase of newly replicated chromosomes and the main relaxase of nucleosomal DNA. Apart from these general tasks, topo II participates in more specialized functions. ...