Visualitza per matèria "Protein interaction networks"

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  • In-silico simulated prototype-patients using TPMS technology to study a potential adverse effect of sacubitril and valsartan
    Jorba Argemí, Guillem; Aguirre Plans, Joaquim, 1993-; Junet, Valentin; Segú-Vergés, Cristina; Ruiz, José Luis; Pujol, Albert; Fernández Fuentes, Narcís; Mas, José Manuel; Oliva Miguel, Baldomero (Public Library of Science (PLoS), 2020)
    Unveiling the mechanism of action of a drug is key to understand the benefits and adverse reactions of a medication in an organism. However, in complex diseases such as heart diseases there is not a unique mechanism of ...
  • Integrative study of gene expression and protein complexes
    Toufighi, Kiana (Universitat Pompeu Fabra, 2016-05-11)
    Over the last several decades, the emerging ‘integrated’ view of the cell has triumphed over the ‘one gene/one protein/one function’ paradigm. This is illustrated by the biologically opposite effects of key regulatory ...
  • Structural analysis of protein interaction networks
    Campagna, Anne (Universitat Pompeu Fabra, 2012-09-19)
    Interactions between proteins give rise to many functions in cells. In the lastdecade, highthroughput experiments have identified thousands of protein interactions, which are often represented together as large protein ...

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