Browsing by Author "Paetzold, Bernhard, 1981-"

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  • Characterization of different alginate lyases for dissolving Pseudomonas aeruginosa biofilms
    Blanco Cabra, Núria; Paetzold, Bernhard, 1981-; Ferrar, Tony; Mazzolini, Rocco; Torrents, Eduard; Serrano Pubull, Luis, 1982-; Lluch-Senar, Maria 1982- (Nature Research, 2020)
    Aggregates of Pseudomonas aeruginosa form a protective barrier against antibiotics and the immune system. These barriers, known as biofilms, are associated with several infectious diseases. One of the main components of ...
  • Cutibacterium acnes strain improvement and establishment of skin microbiome sequencing technologies
    Rozas Belmonte, Miquel (Universitat Pompeu Fabra, 2023-01-11)
    Certain skin disorders are associated with skin microbiome dysbiosis, highlighting the importance of the microbiome in the maintenance of the skin's healthy state. Modulating the microbiome to reestablish its healthy state ...
  • Engineering a genome-reduced bacterium to eliminate Staphylococcus aureus biofilms in vivo
    Garrido, Victoria; Piñero-Lambea, Carlos; Rodriguez-Arce, Irene; Paetzold, Bernhard, 1981-; Ferrar, Tony; Weber, Marc; Garcia Ramallo, Eva; Gallo López, Carolina, 1984-; Collantes, María; Peñuelas, Iván; Serrano Pubull, Luis, 1982-; Grilló, María-Jesús; Lluch-Senar, Maria 1982- (Wiley Open Access, 2021)
    Bacteria present a promising delivery system for treating human diseases. Here, we engineered the genome-reduced human lung pathogen Mycoplasma pneumoniae as a live biotherapeutic to treat biofilm-associated bacterial ...
  • Engineering selectivity of Cutibacterium acnes phages by epigenetic imprinting
    Knödlseder, Nastassia; Nevot, Guillermo; Fábrega, María José; Mir-Pedrol, Júlia; Sanvicente-García, Marta; Campamà-Sanz, Nil; Paetzold, Bernhard, 1981-; Lood, Rolf; Güell Cargol, Marc, 1982- (Public Library of Science (PLoS), 2022)
    Cutibacterium acnes (C. acnes) is a gram-positive bacterium and a member of the human skin microbiome. Despite being the most abundant skin commensal, certain members have been associated with common inflammatory disorders ...
  • From dysbiosis to healthy skin: major contributions of Cutibacterium acnes to skin homeostasis
    Rozas, Miquel; Hart de Ruijter, Astrid; Fábrega, María José; Zorgani, Amine; Güell Cargol, Marc, 1982-; Paetzold, Bernhard, 1981-; Brillet, François (MDPI, 2021)
    Cutibacterium acnes is the most abundant bacterium living in human, healthy and sebum-rich skin sites, such as the face and the back. This bacterium is adapted to this specific environment and therefore could have a major ...
  • Safety and efficacy of topically applied selected cutibacterium acnes strains over five weeks in patients with acne vulgaris: an open-label, pilot study
    Koraglan, Ante; Paetzold, Bernhard, 1981-; Pereira de Lima, Joao; Brüggemann, Holger; Tüting, Thomas; Schanze, Denny; Güell Cargol, Marc, 1982-; Gollnick, Harald (Society for Publication of Acta Dermato-Venereologica, 2019)
    Imbalance in skin microflora, particularly related to certain Cutibacterium acnes strains, may trigger acne. Application of non-acne-causing strains to the skin may modulate the skin microbiome and thereby lead to a reduction ...
  • Skin microbiome modulation induced by probiotic solutions
    Paetzold, Bernhard, 1981-; Willis, Jesse R.; Pereira de Lima, Joao; Knödlseder, Nastassia; Brüggemann, Holger; Quist, Sven Roy; Gabaldón Estevan, Juan Antonio, 1973-; Güell Cargol, Marc, 1982- (BioMed Central, 2019)
    Background: The skin is colonized by a large number of microorganisms, most of which are beneficial or harmless. However, disease states of skin have specific microbiome compositions that are different from those of healthy ...
  • Skin microbiome transplantation and manipulation: Current state of the art
    Callewaert, Chris; Knödlseder, Nastassia; Karoglan, Ante; Güell Cargol, Marc, 1982-; Paetzold, Bernhard, 1981- (Elsevier, 2021)
    Many skin conditions are associated with an imbalance in the skin microbiome. In recent years, the skin microbiome has become a hot topic, for both therapeutic and cosmetic purposes. The possibility of manipulating the ...
  • Synthetic biology in Mycoplasma pneumoniae
    Paetzold, Bernhard, 1981- (Universitat Pompeu Fabra, 2013-12-02)
    M. pneumoniae is one of the smallest self-replicating organisms. Many organism wide studies have been performed on M. pneumoniae and provide a wealth of information on the bacteria. However, the genetic tools to manipulate ...