Visualitza per autor "Nadal Clanchet, Eulàlia de"

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  • Nadal Ribelles, Mariona, 1984-; Solé, Carme; Xu, Zhenyu; Steinmetz, Lars M.; Nadal Clanchet, Eulàlia de; Posas Garriga, Francesc (Elsevier, 2014)
    Genomic analysis has revealed the existence of a large number of long noncoding RNAs (lncRNAs) with different functions in a variety of organisms, including yeast. Cells display dramatic changes of gene expression upon ...
  • Nadal Ribelles, Mariona, 1984- (Universitat Pompeu Fabra, 2013-11-25)
    A fundamental property of living cells is the ability to sense and robustly respond to fluctuations in their environment. In budding yeast (Saccharomyces cerevisiae) changes in extracellular osmolarity are sensed by the ...
  • Zapater Enrique, Meritxell (Universitat Pompeu Fabra, 2006-12-01)
    En el llevat Saccharomyces cerevisiae els canvis en les condicions osmòtiques del medi extracel.lular són sensades per la MAP cinasa Hog1, la qual permet dur a terme l'adaptació cel.lular mitjançant la modulació de l'expressió ...
  • Solé, Carme; Nadal Ribelles, Mariona, 1984-; Kraft, Claudine; Peter, Matthias; Posas Garriga, Francesc; Nadal Clanchet, Eulàlia de (Nature Publishing Group, 2011)
    Protein ubiquitylation is a key process in the regulation of many cellular processes. The balance between the activity of ubiquitin ligases and that of proteases controls the level of ubiquitylation. In response to ...
  • Duch, Alba; Nadal Clanchet, Eulàlia de; Posas Garriga, Francesc (Elsevier, 2013)
    Transcription during S phase needs to be spatially and temporally regulated to prevent collisions between the transcription and replication machineries. Cells have evolved a number of mechanisms to make both processes ...
  • Nadal Ribelles, Mariona, 1984-; Mas Martín, Glòria; Millán Zambrano, Gonzalo; Solé, Carme; Ammerer, Gustav; Chávez, Sebastián; Posas Garriga, Francesc; Nadal Clanchet, Eulàlia de (Oxford University Press, 2015)
    Chromatin remodeling is essential for proper adaptation to extracellular stimuli. The p38-related Hog1 SAPK is an important regulator of transcription that mediates chromatin remodeling upon stress. Hog1 targets the RSC ...
  • Nadal Ribelles, Mariona, 1984-; Conde Pueyo, Núria, 1983-; Flores, Oscar; González-Vallinas Rostes, Juan, 1983-; Eyras Jiménez, Eduardo; Nadal Clanchet, Eulàlia de; Posas Garriga, Francesc (BioMed Central, 2012)
    Cells are subjected to dramatic changes of gene expression upon environmental changes. Stress/ncauses a general down-regulation of gene expression together with the induction of a set of stress-responsive/ngenes. The ...
  • Macía, Javier; Manzoni, Romilde; Conde Pueyo, Núria, 1983-; Urrios, Arturo; Nadal Clanchet, Eulàlia de; Solé Vicente, Ricard, 1962-; Posas Garriga, Francesc (Public Library of Science (PLoS), 2016)
    Engineered synthetic biological devices have been designed to perform a variety of functions from sensing molecules and bioremediation to energy production and biomedicine. Notwithstanding, a major limitation of in vivo ...
  • Stojanovski, Klement; Ferrar, Tony; Benisty, Hannah; Uschner, Friedemann; Delgado, Javier; Jimenez, Javier; Solé, Carme; Nadal Clanchet, Eulàlia de; Klipp, Edda; Posas Garriga, Francesc; Serrano Pubull, Luis, 1982-; Kiel, Christina (Elsevier, 2017)
    The understanding of interaction dynamics in signaling pathways can shed light on pathway architecture and provide insights into targets for intervention. Here, we explored the relevance of kinetic rate constants of a key ...
  • Solé, Carme; Nadal Ribelles, Mariona, 1984-; Nadal Clanchet, Eulàlia de; Posas Garriga, Francesc (Springer, 2015)
    Eukaryotic cells have developed sophisticated systems to constantly monitor changes in the extracellular environment and to orchestrate a proper cellular response. To maximize survival, cells delay cell-cycle progression ...
  • Nadal Clanchet, Eulàlia de; Posas Garriga, Francesc (Wiley, 2015)
    Adaptation is essential for maximizing cell survival and for cell fitness in response to sudden changes in the environment. Several aspects of cell physiology change during adaptation. Major changes in gene expression are ...
  • Ruiz Roig, Clàudia (Universitat Pompeu Fabra, 2011-12-02)
    A Saccharomyces cerevisiae, un increment de la temperatura comporta diversos efectes deleteris en l’organització interna de la cèl∙lula i indueix una inducció ràpida, massiva i transitòria d’expressió gènica, que es controla ...
  • Ruiz Roig, Clàudia; Noriega Esteban, Núria; Duch, Alba; Posas Garriga, Francesc; Nadal Clanchet, Eulàlia de (American Society for Cell Biology, 2012)
    Cells modulate expression of nuclear genes in response to alterations in mitochondrial function, a response termed retrograde (RTG) regulation. In budding yeast, the RTG pathway relies on Rtg1 and Rtg3 basic helix-loop-helix ...
  • Joaquin i Caudet, Manel; Gubern, Albert; González Nuñez, Daniel; Ruiz, E. Josué; Ferreiro Neira, Isabel; Nadal Clanchet, Eulàlia de; Nebreda, Ángel R.; Posas Garriga, Francesc (Nature Publishing Group, 2012)
    The p57(Kip2) cyclin-dependent kinase inhibitor (CDKi) has been implicated in embryogenesis, stem-cell senescence and pathologies, but little is known of its role in cell cycle control. Here, we show that p57(Kip2) is ...
  • Viéitez Manrique, Cristina, 1984- (Universitat Pompeu Fabra, 2014-12-18)
    In response to fluctuations in the environment, all living organisms have the ability to sense, respond and adapt to the new conditions. In budding yeast (Saccharomyces cerevisiae) there is a massive and rapid reorganization ...
  • Noriega Esteban, Núria (Universitat Pompeu Fabra, 2009-02-27)
    La adaptación de la levadura Saccharomyces cerevisiae a condiciones de alta osmolaridad está mediada por la vía de HOG ((high-osmolarity glycerol). La activación de esta vía induce una serie de respuestas que van a permitir ...
  • Casadomé Burriel, Laura (Universitat Pompeu Fabra, 2005-03-01)
    Yeast cells are exposed to a wide variety of environment stresses, among them changes in the osmotic conditions. An osmolar upshift leads to fast loose of intracellular water, so living cells have developed mechanisms to ...