Visualitza per autor "Gundem, Gunes"

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  • Guberman, Jonathan M.; Gundem, Gunes; López Bigas, Núria; Pérez Llamas, Christian, 1976-; Kasprzyk, Arek (Oxford University Press, 2011)
    BioMart Central Portal is a first of its kind, community-driven effort to provide unified access to dozens of biological databases spanning genomics, proteomics, model organisms, cancer data, ontology information and more. ...
  • Gundem, Gunes (Universitat Pompeu Fabra, 2011-09-29)
    In my thesis, I focused on integrative analysis of high-throughput oncogenomic data. This was done in two parts: In the first part, I describe IntOGen, an integrative data mining tool for the study of cancer. This system ...
  • Pérez Llamas, Christian, 1976-; Gundem, Gunes; López Bigas, Núria (Oxford University Press, 2011)
    Recently, we created IntOGen, a resource to integrate a large amount of cancer genomic data. IntOGen aims at facilitating the detection of the most recurrent alterations that drive tumorigenesis. It collates, annotates and ...
  • Gundem, Gunes; Pérez Llamas, Christian, 1976-; Jené i Sanz, Alba, 1984-; Kedzierska, Anna; Islam, Abul, 1978-; Déu Pons, Jordi; Furney, Simon J.; López Bigas, Núria (Universitat Pompeu Fabra, 2010-02)
    Genes and pathways affected by expression and copy number changes in tumors across projects and cancer types.
  • p27
    Pippa, Raffaella; Espinosa Blay, Lluís; Gundem, Gunes; Garcia Escudero, Ramon; Dominguez, Ana; Orlando, S.; Gallastegui, E.; Saiz, Cristina; Besson, Arnaud; Pujol, Maria Jesus; López Bigas, Núria; Paramio, Jesus M.; Bigas Salvans, Anna; Bachs Valldeneu, Oriol (Universitat Pompeu Fabra, 2011-12)
    The cyclin-cdk (cyclin-dependent kinase) inhibitor p27(Kip1) (p27) has a crucial negative role on cell cycle progression. In addition to its classical role as a cyclin-cdk inhibitor, it also performs cyclin-cdk-independent ...
  • Gundem, Gunes; López Bigas, Núria (BioMed Central, 2012)
    Background: Adaptation to stress signals in the tumor microenvironment is a crucial step towards carcinogenic phenotype. The adaptive alterations attained by cells to withstand different types of insults are collectively ...