Kiel, Christina; Benisty, Hannah, 1986-; Lloréns Rico, Verónica, 1989-; Serrano Pubull, Luis, 1982-
(eLife, 2016)
Many driver mutations in cancer are specific in that they occur at significantly higher rates than - presumably - functionally alternative mutations. For example, V600E in the BRAF hydrophobic activation segment (AS) pocket ...