Browsing by Author "Gea Guiral, Joaquim"

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  • Badenes Bonet, Diana (2022-02-25)
    Introducción: Se comparó la oxigenoterapia de alto flujo (OAF) vs. oxigenoterapia convencional (OC) en el tiempo de resistencia (Tlim) de pacientes con FPI y desaturación al esfuerzo. Se estudiaron los predictores de ...
  • Pascual Guàrdia, Sergi, 1979-; Ataya Fernández, Michelle, 1993-; Ramírez Martínez, Isabel; Yélamos López, José; Chalela Rengifo, Roberto José, 1985-; Bellido, Salomé; López-Botet, M. (Miguel); Gea Guiral, Joaquim (BioMed Central, 2020)
    Abstract: Chronic obstructive pulmonary disease (COPD) is a chronic and often progressive disorder with a heterogeneous presentation and frequent systemic manifestations. Several aspects like persistence in smoking habit, ...
  • Gea Guiral, Joaquim (Elsevier, 2020)
  • Mañas García, Laura, 1991-; Denhard, Charlotte; Mateu de Antonio, Francisco Javier; Duran Jordà, Xavier, 1974-; Gea Guiral, Joaquim; Barreiro Portela, Esther (MDPI, 2021)
    We hypothesized that the phenolic compound resveratrol mitigates muscle protein degradation and loss and improves muscle fiber cross-sectional area (CSA) in gastrocnemius of mice exposed to unloading (7dI). In gastrocnemius ...
  • Chalela Rengifo, Roberto José, 1985-; Gallart Gallego, Lluís; Pascual Guàrdia, Sergi, 1979-; Sancho Muñoz, Antonio; Gea Guiral, Joaquim; Orozco Levi, Mauricio (DOVE Medical Press, 2018)
    Background: Hypercapnic encephalopathy is relatively frequent in severe exacerbations of COPD (ECOPDs), with its intensity usually being evaluated through clinical scales. Bispectral index (BIS) is a relatively new technique, ...
  • Balcells Vilarnau, Eva (Universitat Pompeu Fabra, 2016-02-11)
    Introducción: Hay poca información sobre la primera hospitalización por exacerbación de la Enfermedad Pulmonar Obstructiva Crónica (EPOC), a pesar de ser un evento importante en la historia natural de esta enfermedad. El ...
  • Pascual, Sergi (Universitat Pompeu Fabra, 2015-12-10)
    La inflamación y el estrés oxidativo son mecanismos moleculares que contribuyen al daño y a la disfunción muscular. Existen procesos crónicos con fenómenos inflamatorios de bajo grado pero de larga duración (EPOC, con o ...
  • Balcells Vilarnau, Eva, 1967-; Gimeno Santos, Elena, 1980-; De Batlle, Jordi; Ramon, Maria Antonia; Rodríguez, Esther; Benet, Marta; Ferrer, Jaume; Farrero, Eva; Ferrer, Antoni-Lluc, 1942-; Guerra, Stefano; Ferrer, Jaume; Sauleda Roig, Jaume; Barberà, Joan Albert; Agustí García-Navarro, Àlvar; Rodriguez, Robert, 1968-; Gea Guiral, Joaquim; Antó i Boqué, Josep Maria; García Aymerich, Judith (BioMed Central, 2015)
    Background. Under-diagnosis of COPD is an important unmet medical need. We investigated the characteristics and prognosis of hospitalised patients with undiagnosed COPD./nMethods. The PAC-COPD cohort included 342 COPD ...
  • Balcells Vilarnau, Eva, 1967-; Antó i Boqué, Josep Maria; Gea Guiral, Joaquim; Gómez, Federico P.; Rodríguez, Esther; Marin, Alicia; Ferrer, Antoni-Lluc, 1942-; De Batlle, Jordi; Farrero, Eva; Benet, Marta; Orozco Levi, Mauricio; Ferrer, Jaume; Agustí García-Navarro, Àlvar; Gáldiz, Juan B.; Belda, José; García Aymerich, Judith (Elsevier, 2009)
    BACKGROUND: This study describes the characteristics of a large sample of patients hospitalised for the first time for a chronic obstructive pulmonary disease (COPD) exacerbation. METHODS: All subjects first admitted for ...
  • Enríquez Rodríguez, César Jessé; Casadevall Fusté, Carme; Faner, Rosa; Castro Costa, Ady; Pascual Guàrdia, Sergi, 1979-; Seijó Maceiras, Luis; López Campos, José Luis; Peces-Barba Romero, Germán; Monsó Molas, Eduard; Barreiro Portela, Esther; Cosío, Borja G.; Agustí García-Navarro, Àlvar; Gea Guiral, Joaquim; BIOMEPOC group (European Respiratory Society, 2024)
    Background: Some patients with COPD suffer frequent exacerbations (FE). We hypothesised that their systemic proteomic profile would be different from that of non-frequent exacerbators (NFE). The objective of the present ...
  • Sancho Muñoz, Antonio; Guitart, Maria; Rodríguez, Diego; Gea Guiral, Joaquim; Martínez-Llorens, Juana Mª; Barreiro Portela, Esther (Wiley, 2021)
    Sarcopenia is a major comorbidity in chronic obstructive pulmonary (COPD). Whether deficient muscle repair mechanisms and regeneration exist in the vastus lateralis (VL) of sarcopenic COPD remains debatable. In the VL of ...
  • Esteban, Cristóbal; Quintana, José María; García Gutiérrez, Susana; Antón Ladislao, Ane; González, Nerea; Baré, Marisa; Fernández de Larrea-Baz, Nerea; Rivas Ruiz, Francisco; Gea Guiral, Joaquim; IRYSS-COPD group (Dove Medical Press, 2016)
    BACKGROUND: Data are scarce on patient physical activity (PA) level during exacerbations of chronic obstructive pulmonary disease (eCOPD). The objective of the study was to evaluate the level and determinants of change in ...
  • Davidson, Clare; Caguana Vélez, Oswaldo Antonio; Lozano-García, Manuel; Guevara, Mariela Arita; Estrada-Petrocelli, Luis; Ferrer-Lluis, Ignasi; Castillo-Escario, Yolanda; Ausín Herrero, Pilar, 1974-; Gea Guiral, Joaquim; Jané, Raimon (European Respiratory Society, 2023)
    Background: Acute respiratory syndrome due to coronavirus 2 (SARS-CoV-2) is characterised by heterogeneous levels of disease severity. It is not necessarily apparent whether a patient will develop severe disease or not. ...
  • Barreiro Portela, Esther; Sancho Muñoz, Antonio; Puig Vilanova, Ester, 1987-; Salazar Degracia, Anna; Pascual Guàrdia, Sergi, 1979-; Casadevall Fusté, Carme; Gea Guiral, Joaquim (American Physiological Society, 2019)
    Quadriceps muscle weakness and wasting are common comorbidities in chronic obstructive pulmonary disease (COPD). Micro-RNA expression upregulation may favor muscle mass growth and differentiation. We hypothesized that the ...
  • Coronell Coronell, Carlos Gustavo (Universitat Pompeu Fabra, 2011-04-12)
    La Enfermedad Pulmonar Obstructiva Crónica (EPOC), presenta signos y síntomas sistémicos que se han venido explorando desde hace algún tiempo. La presente Tesis Doctoral estudia la disfunción que presentan los músculos ...
  • Puig Vilanova, Ester, 1987-; Ausín Herrero, Pilar, 1974-; Martínez-Llorens, Juana Mª; Gea Guiral, Joaquim; Barreiro Portela, Esther (Public Library of Science (PLoS), 2014)
    Muscle dysfunction is a major comorbidity in Chronic Obstructive Pulmonary Disease (COPD). Several biological mechanisms including epigenetic events regulate muscle mass and function in models of muscle atrophy. Investigations ...
  • Chalela Rengifo, Roberto José, 1985-; González-García, José Gregorio; Khilzi, Karys; Curull Serrano, Víctor; Sánchez Font, Albert; Longarón Rozalen, Raquel; Rodrigo Calvo, Maria Teresa; Martín-Ontiyuelo, Clara; Gea Guiral, Joaquim; Bellosillo Paricio, Beatriz (Frontiers, 2021)
    The acquisition of driver mutations in non-tumoral cells appears to be very important during the carcinogenesis of adenocarcinoma (ADC). Recent studies suggest that cancer-related mutations may not necessarily be present ...
  • Chalela Rengifo, Roberto José, 1985-; Bellosillo Paricio, Beatriz; Curull Serrano, Víctor; Longarón Rozalen, Raquel; Pascual Guàrdia, Sergi, 1979-; Badenes Bonet, Diana, 1987-; Arriola Aperribay, Edurne; Sánchez-Font, Albert; Pijuan Andujar, Lara; Gea Guiral, Joaquim (MDPI, 2019)
    Tumor recurrence is frequent and survival rates remain extremely low in lung adenocarcinoma (ADC). We hypothesize that carcinogenic factors will promote loco-regional modifications not only in the future tumor, but throughout ...
  • Barreiro Portela, Esther; Salazar Degracia, Anna; Sancho Muñoz, Antonio; Aguiló Espases, Rafael; Rodríguez-Fuster, Alberto; Gea Guiral, Joaquim (American Physiological Society, 2019)
    Respiratory muscle dysfunction is common in patients with chronic obstructive pulmonary disease (COPD). Chronic contractile activity induces endoplasmic reticulum (ER) stress and unfolded protein response (UPR) in animals ...
  • Barreiro Portela, Esther; Salazar Degracia, Anna; Sancho Muñoz, Antonio; Gea Guiral, Joaquim (Wiley, 2019)
    mpaired muscle strength and mass (sarcopenia) are common in patients with respiratory cachexia, namely chronic obstructive pulmonary disease (COPD) and in lung cancer (LC)-cachexia. Misfolded/unfolded proteins in endoplasmic ...

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