Visualitza per matèria "Galectin-1"

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  • Characterization of Galectin-1 in Pancreatic Cancer: A sweet target for a bitter disease
    Martínez Bosch, Neus (Universitat Pompeu Fabra, 2012-05-04)
    Pancreatic cancer is nowadays one of the neoplasms with worst prognosis, so research towards the discovery of new molecular targets for therapy and diagnosis is more than urgent. In this direction, we have deeply evaluated ...
  • Gal-1 expression analysis in the GLIOCAT multicenter study: Role as a prognostic factor and an immune-suppressive biomarker
    Martínez Bosch, Neus; Alameda Quitllet, Francisco; Arumí Uría, Montserrat; Bellosillo Paricio, Beatriz; Menéndez, Silvia; Esteve-Codina, Anna; Martínez-García, Maria; Navarro Medrano, Pilar (MDPI, 2023)
    Glioblastoma (GBM) is the most frequent primary malignant brain tumor and has a dismal prognosis. Unfortunately, despite the recent revolution of immune checkpoint inhibitors in many solid tumors, these have not shown a ...
  • Increased plasma levels of galectin-1 in pancreatic cancer: potential use as biomarker
    Martínez Bosch, Neus; Barranco Priego, Luis Eugenio; Orozco, Carlos Alberto; Moreno, Mireia; Visa Turmo, Laura; Iglesias Coma, Mar; Oldfield, Lucy; Neoptolemos, John P.; Greenhalf, William; Earl, Julie; Carrato, Alfredo; Costello, Eithne; Navarro Medrano, Pilar (Impact Journal, 2018)
    Pancreatic ductal adenocarcinoma (PDA) is the most frequent type of pancreatic cancer and one of the deadliest diseases overall. New biomarkers are urgently needed to allow early diagnosis, one of the only factors that ...
  • Role of Galectin-1 in pancreatic cancer stroma, a small but mischievous protein with a novel nuclear function
    Vinaixa Forner, Judit (Universitat Pompeu Fabra, 2019-04-02)
    Pancreatic ductal adenocarcinoma (PDA) is one of the most aggressive tumors; mostly due to its lack of symptoms, resulting in late diagnosis, and also due to the presence of an aggressive tumor microenvironment. Importantly, ...
  • Targeting galectin-1 inhibits pancreatic cancer progression by modulating tumor-stroma crosstalk
    Orozco, Carlos Alberto; Martínez Bosch, Neus; Enrique Guerrero, Pedro; Vinaixa Forner, Judith, 1991-; Dalotto-Moreno, Tomás; Iglesias García, Mar; Moreno, Mireia; Djurec, Magdolna; Poirier, Françoise; Gabius, Hans J.; Fernández-Zapico, Martin E.; Hwang, Rosa F.; Guerra, Carmen; Rabinovich, Gabriel A.; Navarro Medrano, Pilar (National Academy of Sciences, 2018)
    Pancreatic ductal adenocarcinoma (PDA) remains one of the most lethal tumor types, with extremely low survival rates due to late diagnosis and resistance to standard therapies. A more comprehensive understanding of the ...

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