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Browsing by Author "Furlong, Laura I., 1971-"
Now showing items 1-20 of 58
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Gutiérrez-Sacristán, Alba, 1990- (Universitat Pompeu Fabra, 2017-12-15)Estudios clínicos y epidemiológicos muestran que la comorbilidad, la coexistencia de varias enfermedades en un mismo paciente, tiene un gran impacto en la evolución de su estado de salud. Por lo tanto, el análisis de ...
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Li, Tong Shu; Bravo Serrano, Àlex, 1984-; Furlong, Laura I., 1971-; Good, Benjamin M.; Su, Andrew I. (Oxford University Press, 2016)Relations between chemicals and diseases are one of the most queried biomedical interactions. Although expert manual curation is the standard method for extracting these relations from the literature, it is expensive and ...
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Aguirre Plans, Joaquim, 1993-; Piñero González, Janet, 1977-; Souza, Terezinha; Callegaro, Giulia; Kunnen, Steven J.; Sanz, Ferran; Fernández Fuentes, Narcís; Furlong, Laura I., 1971-; Guney, Emre; Oliva Miguel, Baldomero (BioMed Central, 2021)Background: Drug-induced liver injury (DILI) is an adverse reaction caused by the intake of drugs of common use that produces liver damage. The impact of DILI is estimated to affect around 20 in 100,000 inhabitants worldwide ...
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Rebholz-Schuhmann, Dietrich; Furlong, Laura I., 1971-; Rautschka, Michael; Hahn, Udo (BioMed Central, 2011)Background: Competitions in text mining have been used to measure the performance of automatic text processing solutions against a manually annotated gold standard corpus (GSC). The preparation of the GSC is time-consuming ...
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Bauer-Mehren, Anna; van Mulligen, Erik M.; Avillach, Paul; Carrascosa Baena, María Carmen, 1972-; García Serna, Ricard; Piñero González, Janet, 1977-; Singh, Barat; Lopes, Pedro; Oliveira, José Luis; Diallo, Gayo; Ahlberg Helgee, Ernst; Boyer, Scott; Mestres i López, Jordi; Sanz, Ferran; Kors, Jan A.; Furlong, Laura I., 1971- (Public Library of Science (PLoS), 2012)Drug safety issues pose serious health threats to the population and constitute a major cause of mortality worldwide. Due to the prominent implications to both public health and the pharmaceutical industry, it is of great ...
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Bravo Serrano, Àlex, 1984- (Universitat Pompeu Fabra, 2016-11-28)Current biomedical research needs to leverage the large amount of information reported in scientific publications. Automated text processing, commonly known as text mining, has become an indispensable tool to identify, ...
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Pérez-Granado, Judith; Piñero González, Janet, 1977-; Furlong, Laura I., 1971- (Frontiers, 2022)Our knowledge of complex disorders has increased in the last years thanks to the identification of genetic variants (GVs) significantly associated with disease phenotypes by genome-wide association studies (GWAS). However, ...
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Del Toro, N.; Piñero González, Janet, 1977-; Furlong, Laura I., 1971-; Porras, P.; IMEx Consortium Curators (Nature Research, 2019)The current wealth of genomic variation data identified at nucleotide level presents the challenge of understanding by which mechanisms amino acid variation affects cellular processes. These effects may manifest as distinct ...
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Leis Machin, Angela; Mayer, Miguel Ángel, 1960-; Ronzano, Francesco; Torrens, Marta; Castillo, Claudio; Furlong, Laura I., 1971-; Sanz, Ferran (IOS Press, 2020)People use language to express their thoughts and feelings, unveiling important aspects of their psychological traits and social interactions. Although there are several studies describing methodologies to create a collection ...
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Bravo Serrano, Àlex, 1984-; Li, Tong Shu; Su, Andrew I.; Good, Benjamin M.; Furlong, Laura I., 1971- (Oxford University Press, 2016)Drug toxicity is a major concern for both regulatory agencies and the pharmaceutical industry. In this context, text-mining methods for the identification of drug side effects from free text are key for the development of ...
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Martín Sánchez, Ana; Piñero González, Janet, 1977-; Nonell Mazelón, Lara; Arnal, Magdalena; Ribe, Elena; Nevado-Holgado, Alejo J.; Lovestone, Simon; Sanz, Ferran; Furlong, Laura I., 1971-; Valverde, Olga (BioMed Central, 2021)Background: Major depression (MD) is the most prevalent psychiatric disease in the population and is considered a prodromal stage of the Alzheimer's disease (AD). Despite both diseases having a robust genetic component, ...
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Gutiérrez Sacristán, Alba; Bravo Serrano, Àlex, 1984-; Giannoula, Alexia; Mayer, Miguel Ángel, 1960-; Sanz, Ferran; Furlong, Laura I., 1971- (Oxford University Press, 2018)MOTIVATION: The study of comorbidities is a major priority due to their impact on life expectancy, quality of life and healthcare cost. The availability of electronic health records (EHRs) for data mining offers the ...
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Piñero González, Janet, 1977- (Universitat Pompeu Fabra, 2015-12-17)In the last two decades, the volume and variety of biomedical data has dramatically increased. The data is heterogeneous and scattered across many resources. This produces bottlenecks in the analysis and extraction of ...
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Ostaszewski, Marek; Furlong, Laura I., 1971-; Schneider, Reinhard (Nature Research, 2020)Researchers around the world join forces to reconstruct the molecular processes of the virus-host interactions aiming to combat the cause of the ongoing pandemic.
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Leis Machin, Angela; Ronzano, Francesco; Mayer, Miguel Ángel, 1960-; Furlong, Laura I., 1971-; Sanz, Ferran (JMIR Publications, 2019)Background: Mental disorders have become a major concern in public health, and they are one of the main causes of the overall disease burden worldwide. Social media platforms allow us to observe the activities, thoughts, ...
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Queralt Rosinach, Núria; Piñero González, Janet, 1977-; Bravo Serrano, Àlex, 1984-; Sanz, Ferran; Furlong, Laura I., 1971- (Oxford University Press , 2016)MOTIVATION: DisGeNET-RDF makes available knowledge on the genetic basis of human diseases in the Semantic Web. Gene-disease associations (GDAs) and their provenance metadata are published as human-readable and machine-processable ...
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Piñero González, Janet, 1977-; Bravo Serrano, Àlex, 1984-; Queralt Rosinach, Núria; Gutiérrez Sacristán, Alba; Déu Pons, Jordi; Centeno, Emilio; García-García, Javier, 1982-; Sanz, Ferran; Furlong, Laura I., 1971- (Oxford University Press, 2017)The information about the genetic basis of human diseases lies at the heart of precision medicine and drug discovery. However, to realize its full potential to support these goals, several problems, such as fragmentation, ...
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Piñero González, Janet, 1977-; Queralt Rosinach, Núria; Bravo Serrano, Àlex, 1984-; Déu Pons, Jordi; Bauer-Mehren, Anna; Baron, Martin; Sanz, Ferran; Furlong, Laura I., 1971- (Oxford University Press, 2015)DisGeNET is a comprehensive discovery platform designed to address a variety of questions concerning the genetic underpinning of human diseases. DisGeNET contains over 380,000 associations between >16,000 genes and 13,000 ...
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Coloma, Preciosa M.; Furlong, Laura I., 1971-; Bauer-Mehren, Anna; Sanz, Ferran; Mestres i López, Jordi; Sturkenboom, Miriam (Public Library of Science (PLoS), 2013)Background: Drug-related adverse events remain an important cause of morbidity and mortality and impose huge burden on healthcare costs. Routinely collected electronic healthcare data give a good snapshot of how drugs are ...
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Souza, Terezinha; Panuwat, Trairatphisan; Piñero González, Janet, 1977-; Furlong, Laura I., 1971-; Saez-Rodriguez, Julio; Kleinjans, Jos C.; Jennen, Danyel (Frontiers, 2018)In toxicogenomics, functional annotation is an important step to gain additional insights into genes with aberrant expression that drive pathophysiological mechanisms. Nevertheless, there exists a gap on annotation of these ...
Now showing items 1-20 of 58
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