Visualitza per autoria "Farré Albaladejo, Magí"

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  • A biomarker to differentiate between primary and cocaine-induced major depression in cocaine use disorder: the role of platelet IRAS/Nischarin (I1-Imidazoline Receptor)
    Keller, Benjamin; Mestre-Pintó, Juan Ignacio; Álvaro-Bartolomé, María; Martínez-Sanvisens, Diana; Farré Albaladejo, Magí; García-Fuster, M. Julia; García Sevilla, Jesús; Torrens, Marta; The NEURODEP Group (Frontiers, 2017)
    The association of cocaine use disorder (CUD) and comorbid major depressive disorder (MDD; CUD/MDD) is characterized by high prevalence and poor treatment outcomes. CUD/MDD may be primary (primary MDD) or cocaine-induced ...
  • A comparison of acute pharmacological effects of methylone and MDMA administration in humans and oral fluid concentrations as biomarkers of exposure
    Poyatos, Lourdes; Papaseit Fontanet, Esther; Olesti Muñoz, Eulàlia, 1991-; Pérez Mañá, Clara; Ventura, Mireia; Carbón Mallol, Xoán; Grifell Guardia, Marc; Fonseca Casals, Francina, 1972-; Torrens, Marta; Torre Fornell, Rafael de la; Farré Albaladejo, Magí (MDPI, 2021)
    Considered the β-keto analogue of 3,4-methylenedioxymethamphetamine (MDMA, ecstasy), 3,4-Methylenedioxymethcathinone (methylone) is a synthetic cathinone. Over the years, methylone has been used as a substitute for ...
  • A new cognitive evaluation battery for Down syndrome and its relevance for clinical trials
    Sola Llopis, Susana de; Torre Fornell, Rafael de la; Sánchez Benavides, Gonzalo; Benejam, Bessy; Cuenca Royo, Aida Ma, 1981-; Del Hoyo Soriano, Laura; Rodríguez, Joan; Catuara Solarz, Silvina, 1986-; Sánchez Gutiérrez, Judit; Dueñas-Espín, Iván, 1979-; Hernández, Gimena; Peña-Casanova, J. (Jordi); Langohr, Klaus; Videla, Sebastià; Blehaut, Henry; Farré Albaladejo, Magí; Dierssen, Mara; TESDAD Study Group (Frontiers, 2015)
    The recent prospect of pharmaceutical interventions for cognitive impairment of Down syndrome (DS) has boosted a number of clinical trials in this population. However, running the trials has raised some methodological ...
  • A phase 1, randomized double-blind, placebo controlled trial to evaluate safety and efficacy of epigallocatechin-3-gallate and cognitive training in adults with Fragile X syndrome
    Torre Fornell, Rafael de la; De Sola Llopis, Susana; Xicota Vila, Laura, 1987-; Cuenca Royo, Aida Ma, 1981-; Rodriguez, Joan; Gomis González, Maria, 1988-; Hernández, Gimena; Del Hoyo Soriano, Laura; Ozaita Mintegui, Andrés, 1969-; Dierssen, Mara; TESXF Study Group; Principe, Alessandro; Espadaler, Josep María; Roca, Laia; Del Hoyo Soriano, Laura; Farré Albaladejo, Magí; Fitó Colomer, Montserrat; León Jorba, Alba; Banea, Ovideo; Maldonado, Rafael, 1961-; Busquets Garcia, Arnau, 1985- (Elsevier, 2020)
    Background & aims: Despite the wide spectrum of experimental compounds tested in clinical trials, there is still no proven pharmacological treatment available for Fragile-X syndrome (FXS), since several targeted clinical ...
  • Abuse potential of cathinones in humans: a systematic review
    Poyatos, Lourdes; Torres, Adrián; Papaseit Fontanet, Esther; Pérez Mañá, Clara; Hladun, Olga; Núñez-Montero, Melani; de la Rosa, Georgina; Torrens, Marta; Fuster, Daniel; Muga, Roberto; Farré Albaladejo, Magí (MDPI, 2022)
    Introduction and objective: assessing the abuse potential of new substances with central nervous system activity is essential for preventing possible risks of misuse and addiction. The same methodology is recommended for ...
  • Acute effects of 2C-E in humans: an observational study
    Papaseit Fontanet, Esther; Olesti Muñoz, Eulàlia, 1991-; Pérez Mañá, Clara; Torrens, Marta; Grifell Guardia, Marc; Ventura, Mireia; Pozo Mendoza, Óscar J., 1975-; de Sousa Fernandes Perna, Elizabeth B.; Ramaekers, Johannes G.; Torre Fornell, Rafael de la; Farré Albaladejo, Magí (Frontiers, 2020)
    2,5-Dimethoxy-4-ethylphenethylamine (2C-E) is psychedelic phenylethylamine, with a chemical structure similar to mescaline, used as new psychoactive substance (NPS). It inhibits norepinephrine and serotonin uptake and, ...
  • Acute Effects of the Novel Psychoactive Drug 2C-B on Emotions.
    González, Débora; Torrens, Marta; Farré Albaladejo, Magí (Hindawi Publishing Corporation, 2015)
    BACKGROUND: 2C-B (Nexus) is one of the most widespread novel psychoactive substances. There is limited information about its pharmacological properties, and few studies in humans concern its acute and chronic effects. 2C-B ...
  • Acute pharmacological effects of 2C-B in humans: An observational study
    Papaseit Fontanet, Esther; Farré Albaladejo, Magí; Pérez Mañá, Clara; Torrens, Marta; Ventura, Mireia; Pujadas, Mitona; Torre Fornell, Rafael de la; González, Débora (Frontiers, 2018)
    2,5-dimethoxy-4-bromophenethylamine (2C-B) is a psychedelic phenylethylamine derivative, structurally similar to mescaline. It is a serotonin 5-hydroxytryptamine-2A (5-HT2A), 5-hydroxytryptamine-2B (5-HT2B), and ...
  • Acute pharmacological effects of oral and intranasal mephedrone: an observational study in humans
    Papaseit Fontanet, Esther; Olesti Muñoz, Eulàlia, 1991-; Pérez Mañá, Clara; Torrens, Marta; Fonseca Casals, Francina, 1972-; Grifell Guardia, Marc; Ventura, Mireia; Torre Fornell, Rafael de la; Farré Albaladejo, Magí (MDPI, 2021)
    Mephedrone (4-methylmethcathinone) is a synthetic cathinone with psychostimulant properties which remains one of the most popular new psychoactive substances (NPS). It is frequently used orally and/or intranasally. To date, ...
  • Alteración reversible del gusto y del olfato asociada con valproato sódico y quetiapina en la depresión bipolar: a propósito de un caso
    Álvarez López, Pilar; Papaseit Fontanet, Esther; Pérez Solá, Victor; Bulbena Vilarrasa, Antonio; Farré Albaladejo, Magí (Elsevier, 2019)
    Se presenta el caso de un hombre de 47 años, hospitalizado por depresión bipolar con síntomas psicóticos, que presentó disgeusia y cacosmia tras iniciar tratamiento con valproato de sodio. El único tratamiento concomitante ...
  • Analysis of free hydroxytyrosol in human plasma following the administration of olive oil.
    Pastor, Antonio; Rodríguez-Morató, Jose, 1987-; Olesti Muñoz, Eulàlia, 1991-; Pujadas Bastardes, Mitona; Pérez Mañá, Clara; Khymenets, Olha, 1974-; Fitó Colomer, Montserrat; Covas Planells, Maria Isabel; Solà, Rosa; Motilva, Maria-José; Farré Albaladejo, Magí; Torre Fornell, Rafael de la (Elsevier, 2016)
    Hydroxytyrosol (HT) from olive oil, a potent bioactive molecule with health benefits, has a poor bioavailability, its free form (free HT) being undetectable so far. This fact leads to the controversy whether attained HT ...
  • Antidepressant drugs and COVID-19: A review of basic and clinical evidence
    Mas, Marta; García-Vicente, Juan Antonio; Estrada-Gelonch, Anaïs; Pérez Mañá, Clara; Papaseit Fontanet, Esther; Torrens, Marta; Farré Albaladejo, Magí (MDPI, 2022)
    The COVID-19 pandemic has encouraged the repurposing of existing drugs as a shorter development strategy in order to support clinicians with this difficult therapeutic dilemma. There is evidence to support the theory that ...
  • Assessment of efficacy and tolerability of medicinal cannabinoids in patients with multiple sclerosis: a systematic review and meta-analysis
    Torres-Moreno, Mari Carmen; Papaseit Fontanet, Esther; Torrens, Marta; Farré Albaladejo, Magí (American Medical Association, 2018)
    IMPORTANCE: Cannabinoids have antispastic and analgesic effects; however, their role in the treatment of multiple sclerosis (MS) symptoms is not well defined. OBJECTIVE: To conduct a systematic review and meta-analysis to ...
  • BDNF and cortisol in the diagnosis of cocaine-induced depression
    Fonseca Casals, Francina, 1972-; Mestre-Pintó, Juan Ignacio; Rodríguez-Minguela, Rocío; Papaseit Fontanet, Esther; Pérez Mañá, Clara; Langohr, Klaus; Barbuti, Margherita; Farré Albaladejo, Magí; Torrens, Marta; Neurodep Group (Frontiers, 2022)
    Background: Major depressive disorder (MDD) and cocaine use disorder (CUD) are related with disability and high mortality rates. The assessment and treatment of psychiatric comorbidity is challenging due to its high ...
  • Cannabinoids: from pot to lab
    Papaseit Fontanet, Esther; Pérez Mañá, Clara; Pérez-Acevedo, Ana Pilar; Hladun, Olga; Torres-Moreno, Mari Carmen; Muga, Roberto; Torrens, Marta; Farré Albaladejo, Magí (Ivyspring International Publisher, 2018)
    Cannabis is becoming increasingly present in our society. In recent years, the line between the natural (cannabis) and the synthetic (synthetic cannabinoids), the recreational (cannabis) and the medical (pharmaceutical ...
  • Clinical pharmacology of 3,4-methylenedioxymethamphetamine (MDMA, "Ecstasy"): the influence of gender and genetics (CYP2D6, COMT, 5-HTT)
    Pardo Lozano, Ricardo; Farré Albaladejo, Magí; Yubero Lahoz, Samanta, 1985-; O'Mathuna, Brian; Torrens, Marta; Mustata, Cristina; Pérez Mañá, Clara; Langohr, Klaus; Cuyàs, Elisabet; Carbó Banús, Marcel·lí; Torre Fornell, Rafael de la (Public Library of Science (PLoS), 2012)
    The synthetic psychostimulant MDMA (±3,4-methylenedioxymethamphetamine, ecstasy) acts as an indirect serotonin, dopamine, and norepinephrine agonist and as a mechanism-based inhibitor of the cytochrome P-450 2D6 (CYP2D6). ...
  • Complementary phenol-enriched olive oil improves HDL characteristics in hypercholesterolemic subjects. A randomized, double-blind, crossover, controlled trial. The VOHF study
    Farràs Mañé, Marta; Castañer, Olga; Martín-Peláez, Sandra; Hernáez, Álvaro; Schröder, Helmut, 1958-; Subirana Cachinero, Isaac; Muñoz Aguayo, Daniel; Gaixas, Sònia; Torre Fornell, Rafael de la; Farré Albaladejo, Magí; Rubió, Laura; Díaz, Oscar; Fernández-Castillejo, Sara; Solà, Rosa; Motilva, Maria-José; Fitó Colomer, Montserrat (Wiley, 2015)
    Scope: Consumption of olive oil (OO) phenolic compounds (PCs) has beneficial effects on lipid profile. HDL functionality is currently considered to be a more important issue than its circulating quantity. Our aim was to ...
  • Contribution of cytochrome P450 and ABCB1 genetic variability on methadone pharmacokinetics, dose requirements, and response
    Fonseca Casals, Francina, 1972-; Torre Fornell, Rafael de la; Díaz, Laura; Pastor, Antonio; Cuyàs, Elisabet; Pizarro Lozano, Mª Nieves; Khymenets, Olha, 1974-; Farré Albaladejo, Magí; Torrens, Marta (Public Library of Science (PLoS), 2011)
    Although the efficacy of methadone maintenance treatment (MMT) in opioid dependence disorder has been well established, the influence of methadone pharmacokinetics in dose requirement and clinical outcome remains controversial. ...
  • Daidzein modulates cocaine-reinforcing effects and cue-induced cocaine reinstatement in CD-1 male mice
    Martin Casals, Miquel; Gutiérrez Martos, Miriam, 1989-; Cabrera Ortega, Roberto; Langohr, Klaus; Maldonado, Rafael, 1961-; Farré Albaladejo, Magí; Torre Fornell, Rafael de la (Springer, 2021)
    Rationale: Cocaine addiction is a chronic relapsing disorder that lacks of an effective treatment. Isoflavones are a family of compounds present in different plants and vegetables like soybeans that share a common chemical ...
  • The definition of placebo in the informed consent forms of clinical trials
    Hernández Acosta, Astrid; Baños i Díez, Josep Eladi; Llop, Cristina; Farré Albaladejo, Magí (Public Library of Science (PLoS), 2014)
    Aim: Lack of knowledge concerning the nature of placebo and why it is necessary may influence the participation of patients in clinical trials. The objective of the present study is to review how placebo is described in ...

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