Visualitza per autor "Albà Soler, Mar"

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  • Blanco, Enrique; Farré, Domènec; Albà Soler, Mar; Messeguer, Xavier; Guigó Serra, Roderic (Oxford University Press, 2006)
    Information about the genomic coordinates and the sequence of experimentally identified transcription factor binding sites is found scattered under a variety of diverse formats. The availability of standard collections of ...
  • Shikhagaie, Medya (Universitat Pompeu Fabra, 2011-11-07)
    In the present study, we have approached the molecular characterization of the HCMV specific UL1. To this end a HCMV (AD169-derived HB5 background) recombinant with an HA-epitope tagged UL1 and a mutant with a full UL1 ...
  • Mulero, María Carmen; Islam, Abul, 1978-; Margalef González, Pol, 1985-; Pecoraro, Matteo, 1984-; Toll Abelló, Agustín; Drechsel, Nils Jan Daniel, 1980-; Charneco, Cristina; Bellora Pereyra, Nicolás; Gallardo Hernández, Fernando; López Arribillaga, Erika; Asensio Juan, Elena; Rodilla, Verónica; González, Jessica; Iglesias Coma, Mar; Albà Soler, Mar; Di Croce, Luciano; Villà i Freixa, Jordi; López Bigas, Núria; Keyes, William M., 1973-; Bigas Salvans, Anna; Espinosa Blay, Lluís (Elsevier, 2013)
    IκB proteins are the primary inhibitors of NF-κB. Here, we demonstrate that sumoylated and phosphorylated IκBα accumulates in the nucleus of keratinocytes and interacts with histones H2A and H4 at the regulatory region of ...
  • Albà Soler, Mar; Guigó Serra, Roderic (Cold Spring Harbor Laboratory Press-CSHL Press, 2004)
    Amino acid tandem repeats, also called homopolymeric tracts, are extremely abundant in eukaryotic proteins. To gain insight into the genome-wide evolution of these regions in mammals, we analyzed the repeat content in a ...
  • Mularoni, Loris (Universitat Pompeu Fabra, 2009-07-28)
    Tandem amino acid repeats, also known as homopolimeric tract or homopeptides, are very common features of eukaryotic genomes and are present in nearly one-fifth of human encoded proteins. These structures have attracted ...
  • Furney, Simon J.; Albà Soler, Mar; López Bigas, Núria (BioMed Central, 2006)
    Background: Global analyses of human disease genes by computational methods have yielded important advances in the understanding of human diseases. Generally these studies have treated the group of disease genes uniformly, ...
  • Radó i Trilla, Núria, 1985-; Albà Soler, Mar (BioMed Central, 2012)
    Low-complexity regions (LCRs) in proteins are tracts that are highly enriched in one or a few aminoacids. Given their high abundance, and their capacity to expand in relatively short periods of time through replication ...
  • Ledda, Alice (Universitat Pompeu Fabra, 2011-05-06)
    Els microsat el lits s on seq u encies d'ADN formades per repeticions ent andem de motius curts. Les curtes seq u encies repetides en t andem s onubiq ues en els genomes dels eucariotes, tant en les regions codi cants comen ...
  • Toll-Riera, Macarena; Albà Soler, Mar (BioMed Central, 2013)
    Proteins are composed of a combination of discrete, well-defined, sequence domains, associated with specific functions that have arisen at different times during evolutionary history. The emergence of novel domains is ...
  • Huang, Hui; Winter, Eitan E; Wang, Huajun; Weinstock, Keith G; Xing, Heming; Goodstadt, Leo; Stenson, Peter D; Cooper, David N; Smith, Douglas; Albà Soler, Mar; Ponting, Chris P; Fechtel, Kim (BioMed Central, 2004)
    Background: Model organisms have contributed substantially to our understanding of the etiology of human disease as well as having assisted with the development of new treatment modalities. The availability of the human, ...
  • Faherty, Sheena L.; Villanueva Cañas, José Luis, 1984-; Klopfer, Peter H.; Albà Soler, Mar; Yoder, Anne D. (Oxford University Press, 2016)
    Hibernation is a complex physiological response that some mammalian species employ to evade energetic demands. Previous work in mammalian hibernators suggests that hibernation is activated not by a set of genes unique to ...
  • Santpere, Gabriel; Darre, Fleur; Blanco, Soledad; Alcami, Antonio; Villoslada, Pablo; Albà Soler, Mar; Navarro i Cuartiellas, Arcadi, 1969- (Oxford University Press, 2014)
    Most people in the world (∼90%) are infected by the Epstein–Barr virus (EBV), which establishes itself permanently in B cells. Infection by EBV is related to a number of diseases including infectious mononucleosis, multiple ...
  • Baldo, Laura; Riera, Joan Lluís; Tooming-Klunderud, Ave; Albà Soler, Mar; Salzburger, Walter (Public Library of Science, 2015)
    The gut microbiota structure reflects both a host phylogenetic history and a signature of adaptation to the host ecological, mainly trophic niches. African cichlid fishes, with their array of closely related species that ...
  • Subirana, Juan A.; Albà Soler, Mar; Messeguer, Xavier (BioMed Central, 2015)
    Background. The high density of tandem repeat sequences (satellites) in nematode genomes and the availability of genome sequences from several species in the group offer a unique opportunity to better understand the ...
  • Furney, Simon J.; Albà Soler, Mar; López Bigas, Núria (Universitat Pompeu Fabra, 2006-07)
    Database of human genes prioritized for their probability of involvement in dominant or recessive hereditary diseases.
  • Villanueva Cañas, José Luis, 1984-; Laurie, Steven, 1973-; Albà Soler, Mar (Oxford University Press, 2013)
    Large-scale evolutionary studies often require the automated construction of alignments of a large number of homologous gene families. The majority of eukaryotic genes can produce different transcripts due to alternative ...
  • Bellora Pereyra, Nicolás (Universitat Pompeu Fabra, 2010-02-26)
    Regulation of gene transcription is a complex process involving many different proteins, some of which bind in a sequence-specific manner to DNA motifs in the gene promoter. The need to maintain specific interactions between ...
  • Villanueva Cañas, José Luis, 1984- (Universitat Pompeu Fabra, 2015-11-20)
    Although the genome sequencing revolution is still in its infancy, we must acknowledge it as the major driver of biology since the beginning of the 21st century. The availability of a large collection of complete mammalian ...
  • Radó i Trilla, Núria, 1985-; Arató, Krisztina, 1981-; Pegueroles Queralt, Maria Cinta; Raya, Alicia; Luna, Susana de la; Albà Soler, Mar (Open University Press, 2015)
    The high regulatory complexity of vertebrates has been related to two rounds of whole genome duplication (2R-WGD) that occurred before the divergence of the major vertebrate groups. Following these events, many developmental ...
  • Ruiz Orera, Jorge, 1988-; Messeguer, Xavier; Subirana, Juan A.; Albà Soler, Mar (eLife, 2014)
    Deep transcriptome sequencing has revealed the existence of many transcripts that lack long or conserved open reading frames (ORFs) and which have been termed long non-coding RNAs (lncRNAs). The vast majority of lncRNAs ...