Visualitza per autoria "Abad, María"

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  • pTINCR microprotein promotes epithelial differentiation and suppresses tumor growth through CDC42 SUMOylation and activation
    Boix, Olga; Albà Soler, Mar; Abad, María (Nature Research, 2022)
    The human transcriptome contains thousands of small open reading frames (sORFs) that encode microproteins whose functions remain largely unexplored. Here, we show that TINCR lncRNA encodes pTINCR, an evolutionary conserved ...
  • Transcriptional regulation of Sox2 by the retinoblastoma family of pocket proteins
    Vilas, Jéssica M.; Ferreirós, Alba; Carneiro, Carmen; Morey Ramonell, Lluís; Silva-Álvarez, Sabela da; Fernandes, Tânia; Abad, María; Di Croce, Luciano; García Caballero, Tomás; Serrano, Manuel; Rivas, Carmen; Vidal, Anxo; Collado, Manuel (Impact Journals, 2015)
    Cellular reprogramming to iPSCs has uncovered unsuspected links between tumor suppressors and pluripotency factors. Using this system, it was possible to identify tumor suppressor p27 as a repressor of Sox2 during ...
  • TUNAR lncRNA encodes a microprotein that regulates neural differentiation and neurite formation by modulating calcium dynamics
    Senís, Elena; Esgleas, Miriam; Najas Sales, Sònia, 1985-; Jiménez-Sábado, Verónica; Bertani, Camilla; Giménez-Alejandre, Marta; Escriche, Alba; Ruiz Orera, Jorge, 1988-; Hergueta-Redondo, Marta; Jiménez, Mireia; Giralt, Albert; Nuciforo, Paolo G.; Albà Soler, Mar; Peinado, Héctor; Toro, Daniel; Hove-Madsen, Leif; Götz, Magdalena; Abad, María (Frontiers, 2021)
    Long noncoding RNAs (lncRNAs) are regulatory molecules which have been traditionally considered as "non-coding". Strikingly, recent evidence has demonstrated that many non-coding regions, including lncRNAs, do in fact ...

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