Browsing by Subject "S. pombe"

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  • A functional genome-wide genetic screening identifies new pathways controlling the G1/S transcriptional wave
    Gaspa, Laura; González Medina, Alberto, 1990-; Hidalgo Hernando, Elena; Ayté del Olmo, José (Taylor & Francis (Routledge), 2016)
    The Schizosaccharomyces pombe MBF complex activates the transcription of genes required for DNA synthesis and S phase. The MBF complex contains several proteins, including the core components Cdc10, Res1 and Res2, the ...
  • Función biológica y regulación de la ciclina específica de meiosis Rem1 en Schizosaccharomyces Pombe
    Malapeira Argilaga, Jordi (Universitat Pompeu Fabra, 2006-11-30)
    Esta tesis doctoral consiste en la caracterización de la ciclina meiótica Rem1, de Schizosaccharomyces pombe. En este trabajo se analizó, inicialmente, el patrón de transcripción y expresión de rem1 durante la meiosis ...
  • Genetic and epigenetic mechanisms regulating the G1-S transcriptional wave in fission yeast
    González Medina, Alberto, 1990- (Universitat Pompeu Fabra, 2019-03-01)
    The control of proper progression of eukaryotic cell cycle is essential if cells want to continue proliferating appropriately, and it is a conserve feature from yeast to human cells. One of the most important points of ...
  • INO80 complex regulates the G1-to-S transcriptional wave through MBF
    Knezevic, Iva, 1984- (Universitat Pompeu Fabra, 2015-07-17)
    In eukaryotic cells a key regulatory step of cell cycle occurs in late G1, which has been termed “Start” in yeast cells. At this point, cells determine whether they will go to through a new round of proliferation, or choose ...
  • Promoter nucleosome dynamics regulated by signalling through the CTD code
    Materne, Philippe; Anandhakumar, Jayamani; Migeot, Valerie; Soriano, Ignacio; Yague Sanz, Carlo; Hidalgo Hernando, Elena; Mignion, Carole; Quintales, Luis; Antequera, Francisco; Hermand, Damien (eLife, 2015)
    The phosphorylation of the RNA polymerase II C-terminal domain (CTD) plays a key role in delineating transcribed regions within chromatin by recruiting histone methylases and deacetylases. Using genome-wide nucleosome ...
  • Thiol-based H2O2 signalling in microbial systems
    Boronat i Llop, Susanna, 1965-; Domènech, Alba; Paulo Mirasol, Esther, 1984-; Calvo, Isabel A.; García Santamarina, Sarela, 1978-; García, Patrícia; Encinar del Dedo, Javier; Barcons-Simon, Anna; Serrano, Erica; Carmona, Mercè; Hidalgo Hernando, Elena (Elsevier, 2014)
    Cysteine residues, and in particular their thiolate groups, react not only with reactive oxygen species but also with electrophiles and with reactive nitrogen species. Thus, cysteine oxidation has often been linked to the ...