Browsing by Subject "H2A.Z"

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  • New insights into the role of oxidized histone H3 in heterochromatin
    Serra Bardenys, Gemma (Universitat Pompeu Fabra, 2020-01-07)
    Oxidation of histone H3 (H3K4ox) by lysyl oxidase-like 2 (LOXL2) is important in triple-negative breast cancer (TNBC) cells to generate compacted heterochromatin regions. However, the molecular mechanisms by which it ...
  • The DREAM complex promotes gene body H2A.Z for target repression
    Latorre, Isabel; Chesney, Michael A.; Garrigues, Jacob M.; Stempor, Przemyslaw; Appert, Alex; Francesconi, Mirko; Strome, Susan; Ahringer, Julie (Cold Spring Harbor Laboratory Press, 2015)
    The DREAM (DP, Retinoblastoma [Rb]-like, E2F, and MuvB) complex controls cellular quiescence by repressing cell cycle genes, but its mechanism of action is poorly understood. Here we show that Caenorhabditis elegans DREAM ...

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