Browsing by Subject "G1 phase"

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  • Role of DYRK1A in the development of the cerebral cortex : Implication in Down Syndrome
    Najas Sales, Sònia, 1985- (Universitat Pompeu Fabra, 2016-05-11)
    In this work we have assessed the possible contribution of the human chromosome-21 gene DYRK1A in the developmental cortical alterations associated with Down Syndrome using the mBACTgDyrk1a mouse, which carries 3 copies ...
  • Wnt/Tcf1 pathway restricts embryonic stem cell cycle through activation of the Ink4/Arf locus
    de Jaime Soguero, Anchel; Aulicino, Francesco, 1987-; Ertaylan, Gokhan; Griego, Anna; Cerrato, Aniello; Tallam, Aravind; del Sol, Antonio; Cosma, Maria Pia, 1970-; Lluis Vinas, Frederic (Public Library of Science (PLoS), 2017)
    Understanding the mechanisms regulating cell cycle, proliferation and potency of pluripotent stem cells guarantees their safe use in the clinic. Embryonic stem cells (ESCs) present a fast cell cycle with a short G1 phase. ...

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