Browsing by Subject "G-protein-coupled receptors"

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  • Identification of a tool compound to study the mechanisms of functional selectivity between D-2 and D-3 dopamine receptors
    Reyes-Resina, Irene; Samadi, Abdelouahid; Navarro, Gemma; Saadeh, Haythem A.; Khasawneh, Mohammad A.; Mestres i López, Jordi; Marco-Contelles, José; Franco, Rafael (American Chemical Society (ACS), 2018)
    The search for synthetic selective compounds for G-protein-coupled receptors has provided a myriad of molecules with high selectivity and therapeutic potential. In some cases, however, selectivity is difficult to obtain. ...
  • Phosphorylation of filamin A regulates chemokine receptor CCR2 recycling
    Pons, Mónica; Izquierdo, Ismael; Andreu-Carbó, Mireia; Garrido, Georgina; Planagumà, Jesús; Muriel, Olivia; Pozo, Miguel Ángel del; Isabel Geli, M.; Aragay, Anna M. (Company of Biologists, 2017)
    Proper endosomal trafficking of ligand-activated G-protein-coupled receptors (GPCRs) is essential to spatiotemporally tune their physiological responses. For the monocyte chemoattractant receptor 2 (CCR2B; one of two ...