Listar por tema "B cells"

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  • B cells and tertiary lymphoid structures influence survival in lung cancer patients with resectable tumors
    Tang, Jun; Ramis Cabrer, Daniel, 1993-; Curull Serrano, Víctor; Wang, Xuejie; Mateu Jiménez, Mercè, 1990-; Pijuan Andujar, Lara; Duran, Xavier; Qin, Liyun; Rodríguez-Fuster, Alberto; Aguiló Espases, Rafael; Barreiro Portela, Esther (MDPI, 2020)
    Immune profile of B and T cells and tertiary lymphoid structures (TLSs) may differ in tumors of lung cancer (LC) patients with/without chronic obstructive pulmonary disease (COPD), and may also influence patient survival. ...
  • Dynamic cross-regulation of antigen-specific effector and regulatory T cell subpopulations and microglia in brain autoimmunity
    Martínez Pasamar, Sara; Abad Adan, Elena; Moreno, Beatriz; Vélez de Mendizábal, Nieves; Martínez Forero, Ivan; García Ojalvo, Jordi; Villoslada, Pablo (BioMed Central, 2013)
    Background: Multiple Sclerosis (MS) is considered a T-cell-mediated autoimmune disease with a prototypical oscillatory behavior, as evidenced by the presence of clinical relapses. Understanding the dynamics of immune cells ...
  • Epstein-Barr virus+ B cells in breast cancer immune response: a case report
    Aran, Andrea; Peg, Vicente; Rabanal, Rosa María; Bernadó, Cristina; Zamora, Esther; Molina, Elisa; Arribas, Yago A.; Arribas, Joaquín; Pérez, José; Roura-Mir, Carme; Carrascal, Montserrat; Cortés, Javier; Martí, Mercè (Frontiers, 2021)
    EBV-specific T cells have been recently described to be involved in fatal encephalitis and myocarditis in cancer patients after immune checkpoint therapies. Here, we report the study of a human triple-negative breast cancer ...
  • Impact of cytomegalovirus infection on B cell differentiation and cytokine production in multiple sclerosis
    Zabalza, Ana; Vera, Andrea; Alari-Pahissa, Elisenda; Munteis Olivas, Elvira; Moreira Villanueva, Antía; Yélamos López, José; Llop, Mireia; López-Botet, M. (Miguel); Martínez Rodríguez, Jose E. (BioMed Central, 2020)
    Background: Human cytomegalovirus (HCMV) infection has been recently associated with a low risk of multiple sclerosis (MS), yet the basis behind this observation remains uncertain. In this study, we aimed to determine in ...
  • NK cells eliminate Epstein-Barr virus bound to B cells through a specific antibody-mediated uptake
    Alari-Pahissa, Elisenda; Ataya Fernández, Michelle, 1993-; Moraitis, Ilias; Campos Ruiz, Miriam; Altadill, Mireia; Muntasell i Castellví, Aura, 1972-; Moles, Anna; López-Botet, M. (Miguel) (Public Library of Science (PLoS), 2021)
    Epstein Barr virus (EBV) causes a highly prevalent and lifelong infection contributing to the development of some malignancies. In addition to the key role played by T cells in controlling this pathogen, NK cells mediate ...
  • Regulation of B cell responses by the innate immune system
    Cerutti, Andrea (Universitat Pompeu Fabra, 2013-09-06)
    Immunoglobulin (Ig) diversification is essential for the generation of protective immune responses against intruding microbes. B cells require cognate interaction with T cells to generate protective antibodies, although ...
  • Role of mTOR in the activation of marginal zone B cells by TACI
    Gentile, Maurizio (Universitat Pompeu Fabra, 2015-11-10)
    The marginal zone (MZ) of the spleen contains an innate-like subset of B cells that mount rapid protective antibody responses to polysaccharides and lipids from bloodborne viruses and bacteria. These antigens activate MZ ...
  • Teleost IgD + IgM - B cells mount clonally expanded and mildly mutated intestinal IgD responses in the absence of lymphoid follicles
    Perdiguero, Pedro; Martín-Martín, Alba; Benedicenti, Ottavia; Díaz-Rosales, Patricia; Morel, Esther; Muñoz-Atienza, Estefanía; García-Flores, Mónica; Simón, Rocío; Soleto, Irene; Cerutti, Andrea, 1965-; Tafalla, Carolina (Elsevier, 2019)
    Immunoglobulin D (IgD) is an ancient antibody with dual membrane-bound and fluid-phase antigen receptor functions. The biology of secreted IgD remains elusive. Here, we demonstrate that teleost IgD+IgM- plasmablasts ...

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