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Browsing by Subject "Ab-amyloid fibrils"

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Stable complexes involving acetylcholinesterase and amyloid-ß-peptide change the biochemical properties of the enzyme and increase the neurotoxicity of Alzheimer's fibrils

Álvarez, Alejandra R.; Alarcón Martínez, Rodrigo; Opazo, Carlos M.; Campos, Eliseo O.; Muñoz López, Francisco José, 1964-; Calderón, Frances H.; Dajas, Federico; Gentry, Mary K.; Doctor, Bhupendra P.; Mello, Fernando G. de; Inestrosa, Nibaldo C. (Society for Neuroscience, 1998)

Brain acetylcholinesterase (AChE) forms stable complexes with amyloid-beta peptide (Abeta) during its assembly into filaments, in agreement with its colocalization with the Abeta deposits of Alzheimer's brain. The association ...

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