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Browsing by Subject "616.6"
Now showing items 1-20 of 24
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(2021-04-09)Cytomegalovirus (CMV) infection in kidney transplant recipients (KTR) is frequent and may reduce graft and patient survival. T lymphocytes are essential to control the virus, which promotes the adaptive differentiation of ...
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(Universitat Pompeu Fabra, 2018-12-20)El càncer de bufeta avançat s'associa amb un mal pronòstic i amb opcions limitades de tractament. Tot i l’èxit recent amb l'ús d'inhibidors immunitaris, no tots els pacients responen a la teràpia i encara hi ha la necessitat ...
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(Universitat Pompeu Fabra, 2011-09-20)Migraine is one of most disabling neurological disorders for which the genetic and molecular mechanisms are not fully resolved. This PhD thesis has focused on the functional characterization of two new missense mutations ...
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(Universitat Pompeu Fabra, 2019-01-10)The centrosome is an essential organelle for the development of a new organism in animals. Upon fertilization the spermatozoon enters into the oocyte providing its basal body that converts into the first centrosome of the ...
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(Universitat Pompeu Fabra, 2018-07-23)This thesis performs the comparison on patient-reported outcomes (health-related quality of life and patients’ preferences) among radical prostatectomy, external radiotherapy and brachytherapy, in the “Spanish Multicentric ...
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(2021-04-09)Short explanation English To reveal how RBM10 loss contributes to development and cancer we have established Rbm10 constitutive and conditional knockout mouse models and have analyzed phenotypes at the organismal and ...
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(2021-04-30)In recent years considerable progress has been made in the development of approaches for human pluripotent stem cells (hPSCs) differentiation. An important step in this direction has been the derivation of hPSCs derived ...
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(Universitat Pompeu Fabra, 2011-04-12)La present tesi avalua les diferències entre homes i dones quant a les característiques sociodemogràfiques i clínicopatològiques, procés diagnòstic, tractament i pronòstic en una sèrie de casos diagnosticats de novo de ...
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(2022-05-09)S'han identificat dues vies carcinogèniques en el càncer de pròstata (CaPr): la positiva i la negativa per a fusions dels gens ETS. L’objectiu d’aquest estudi ha estat entendre el significat biològic i la posició jeràrquica ...
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(2021-06-02)Dent disease 1 (DD1) is a rare renal tubulopathy caused by CLCN5 mutations and characterized by low molecular weight proteinuria, variable hypercalciuria, nephrocalcinosis and/or nephrolithiasis and progression to kidney ...
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(Universitat Pompeu Fabra, 2016-06-10)Polycomblike proteins (PCLs) have been shown to regulate Polycomb Repressive Complex 2 (PRC2) by enhancing its catalytic activity and guiding PRC2 to its target genes in embryonic stem cells. However, little is known about ...
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(Universitat Pompeu Fabra, 2017-06-14)L'objectiu global d'aquesta tesi va ser avaluar l'eficiència, des de la perspectiva dels sistemes de salut, dels tractaments més establerts per als pacients diagnosticats amb càncer de pròstata localitzat. El "Estudi ...
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(Universitat Pompeu Fabra, 2018-01-24)Prostate cancer (PrCa) is a highly heterogeneous disease and its prognosis, diagnosis and management are still controversial. ERG rearrangements and PTEN loss are frequent and concomitant events in a subset of PrCa. The ...
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(Universitat Pompeu Fabra, 2011-04-12)L'objectiu d'aquest tesi és avaluar els diferents passos en el camí que va des de l'exposició a contaminants atmosfèrics/PAHs fins a la malaltia, el càncer de bufeta urinària. Es van mesurar partícules ultrafines a Barcelona. ...
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(2021-05-10)The splicing regulatory protein RBM10 is frequently mutated in bladder carcinomas. Analysis of RNA sequencing data of 476 bladder tumours (UROMOL) identified 469 alternative splicing (AS) events associated with RBM10 ...
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(2022-04-22)High-grade serous carcinoma (HGSC) is the most common and deadly subtype of ovarian cancer. It is characterised by presenting defects in the homologous recombination repair, most frequently associated to BRCA1 mutations. ...
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(Universitat Pompeu Fabra, 2016-05-18)P63 is a transcription factor of the p53 family with key roles in embryonic development, stem cells and cancer. P63-deficient mice fail to form stratified and glandular epithelia, including the prostate, demonstrating a ...
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(Universitat Pompeu Fabra, 2018-06-21)En esta tesis doctoral se han evaluado indicadores asociados a las principales estrategias propuestas de cribado vigentes en Catalunya desde el año 2006, incluyendo la evaluación de la participación en el cribado, intervalo ...
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(Universitat Pompeu Fabra, 2014-09-03)The overall objective of this thesis was to describe the evolution of Health-Related Quality of Life in Spanish patients with urologic tumours; and to the examine clinical and treatment-related factors associated with ...
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(Universitat Pompeu Fabra, 2015-11-17)Polyomaviruses are suspected to cause cancer in humans although to date Merkel cell polyomavirus (MCPyV) is the only proven human carcinogen. Potential associations of up to nine polyomaviruses with 468 lymphoproliferative ...
Now showing items 1-20 of 24
