Browsing by Author "van Berckel, Bart N. M."

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  • Heeman, Fiona; Yaqub, Maqsood; Hendriks, Janine; van Berckel, Bart N. M.; Collij, Lyduine E.; Gray, Katherine R.; Manber, Richard; Wolz, Robin; Garibotto, Valentina; Wimberley, Catriona; Ritchie, Craig; Barkhof, Frederik; Gispert López, Juan Domingo; Vállez García, David; Lopes Alves, Isadora; Lammertsma, Adriaan A.; AMYPAD Consortium (SpringerOpen, 2022)
    Background: despite its widespread use, the semi-quantitative standardized uptake value ratio (SUVR) may be biased compared with the distribution volume ratio (DVR). This bias may be partially explained by changes in ...
  • Heeman, Fiona; Yaqub, Maqsood; Hendriks, Janine; Bader, Ilona; Barkhof, Frederik; Gispert López, Juan Domingo; van Berckel, Bart N. M.; Lopes Alves, Isadora; Lammertsma, Adriaan A. (Elsevier, 2021)
    Optimal pharmacokinetic models for quantifying amyloid beta (Aβ) burden using both [18F]flutemetamol and [18F]florbetaben scans have previously been identified at a region of interest (ROI) level. The purpose of this study ...
  • Collij, Lyduine E.; Mastenbroek, Sophie E.; Salvadó, Gemma; Wink, Alle Meije; Visser, Pieter Jelle; Barkhof, Frederik; van Berckel, Bart N. M.; Lopes Alves, Isadora (Elsevier, 2021)
    Introduction: The value of quantitative longitudinal and regional amyloid beta (Aβ) measurements in predicting cognitive decline in initially cognitively unimpaired (CU) individuals remains to be determined. Methods: We ...
  • Lopes Alves, Isadora; Heeman, Fiona; Collij, Lyduine E.; Salvadó, Gemma; Tolboom, Nelleke; Vilor Tejedor, Natàlia, 1988-; Markiewicz, Pawel; Yaqub, Maqsood; Cash, David; Mormino, Elizabeth C.; Insel, Philip S.; Boellaard, Ronald; van Berckel, Bart N. M.; Lammertsma, Adriaan A.; Barkhof, Frederik; Gispert López, Juan Domingo (BioMed Central, 2021)
    Background: Detecting subtle-to-moderate biomarker changes such as those in amyloid PET imaging becomes increasingly relevant in the context of primary and secondary prevention of Alzheimer's disease (AD). This work aimed ...
  • Collij, Lyduine E.; Salvadó, Gemma; Shekari, Mahnaz; Lopes Alves, Isadora; Reimand, Juhan; Wink, Alle Meije; Zwan, Marissa; Niñerola-Baizán, Aida; Perissinotti, Andrés; Scheltens, Philip; Ikonomovic, Milos D.; Smith, Adrian P.L.; Farrar, Gill; Molinuevo, José Luis; Barkhof, Frederik; Buckley, Christopher, 1948-; van Berckel, Bart N. M. (Springer, 2021)
    Purpose: To investigate the sensitivity of visual read (VR) to detect early amyloid pathology and the overall utility of regional VR. Methods: [18F]Flutemetamol PET images of 497 subjects (ALFA+ N = 352; ADC N = 145) were ...

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