Browsing by Author "Vohryzek, Jakub"

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  • Distributed harmonic patterns of structure-function dependence orchestrate human consciousness
    Luppi, Andrea I.; Vohryzek, Jakub; Kringelbach, Morten L.; Martinez Mediano, Pedro Antonio; Adapa, Ram; Carhart-Harris, Robin L.; Roseman, Leor; Pappas, Ioannis; Peattie, Alexander R. D.; Manktelow, Anne E.; Sahakian, Barbara J.; Finoia, Paola; Williams, Guy B.; Allanson, Judith; Pickard, John D.; Menon, David K.; Atasoy, Selen; Stamatakis, Emmanuel A. (Nature Research, 2023)
    A central question in neuroscience is how consciousness arises from the dynamic interplay of brain structure and function. Here we decompose functional MRI signals from pathological and pharmacologically-induced perturbations ...
  • Dynamic sensitivity analysis: defining personalised strategies to drive brain state transitions via whole brain modelling
    Vohryzek, Jakub; Cabral, Joana; Castaldo, Francesca; Sanz-Perl, Yonatan; Lord, Louis-David; Fernandes, Henrique M.; Litvak, Vladimir; Kringelbach, Morten L.; Deco, Gustavo (Elsevier, 2023)
    Traditionally, in neuroimaging, model-free analyses are used to find significant differences between brain states via signal detection theory. Depending on the a priori assumptions about the underlying data, different ...
  • Effects of classic psychedelic drugs on turbulent signatures in brain dynamics
    Cruzat Grand, Josefina, 1983-; Sanz Perl, Yonatan; Escrichs, Anira; Vohryzek, Jakub; Timmermann, Christopher; Roseman, Leor; Luppi, Andrea I.; Ibañez, Agustin; Nutt, David; Carhart-Harris, Robin L.; Tagliazucchi, Enzo; Deco, Gustavo; Kringelbach, Morten L. (MIT Press, 2022)
    Psychedelic drugs show promise as safe and effective treatments for neuropsychiatric disorders, yet their mechanisms of action are not fully understood. A fundamental hypothesis is that psychedelics work by dose-dependently ...
  • Ghost attractors in spontaneous brain activity: recurrent excursions into functionally-relevant BOLD phase-locking states
    Vohryzek, Jakub; Deco, Gustavo; Cessac, Bruno; Kringelbach, Morten L.; Cabral, Joana (Frontiers, 2020)
    Functionally relevant network patterns form transiently in brain activity during rest, where a given subset of brain areas exhibits temporally synchronized BOLD signals. To adequately assess the biophysical mechanisms ...
  • Metastable oscillatory modes emerge from synchronization in the brain spacetime connectome
    Cabral, Joana; Castaldo, Francesca; Vohryzek, Jakub; Litvak, Vladimir; Bick, Christian; Lambiotte, Renaud; Friston, Karl; Kringelbach, Morten L.; Deco, Gustavo (Nature Research, 2022)
    A rich repertoire of oscillatory signals is detected from human brains with electro- and magnetoencephalography (EEG/MEG). However, the principles underwriting coherent oscillations and their link with neural activity ...
  • Moving from phenomenological to predictive modelling: progress and pitfalls of modelling brain stimulation in-silico
    Kurtin, Danielle L.; Giunchiglia, Valentina; Vohryzek, Jakub; Cabral, Joana; Skeldon, Anne C.; Violante, Ines R. (Elsevier, 2023)
    Brain stimulation is an increasingly popular neuromodulatory tool used in both clinical and research settings; however, the effects of brain stimulation, particularly those of non-invasive stimulation, are variable. This ...
  • The lack of temporal brain dynamics asymmetry as a signature of impaired consciousness states
    G-Guzmán, Elvira; Sanz Perl, Yonatan; Vohryzek, Jakub; Escrichs, Anira; Manasova, Dragana; Türker, Basak; Tagliazucchi, Enzo; Kringelbach, Morten L.; Sitt, Jacobo; Deco, Gustavo (Royal Society, 2023)
    Life is a constant battle against equilibrium. From the cellular level to the macroscopic scale, living organisms as dissipative systems require the violation of their detailed balance, i.e. metabolic enzymatic reactions, ...
  • Understanding brain states across spacetime informed by whole-brain modelling
    Vohryzek, Jakub; Cabral, Joana; Vuust, Peter; Deco, Gustavo; Kringelbach, Morten L. (Royal Society, 2022)
    In order to survive in a complex environment, the human brain relies on the ability to flexibly adapt ongoing behaviour according to intrinsic and extrinsic signals. This capability has been linked to specific whole-brain ...