Browsing by Author "Vizán, Pedro"

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  • Bogu, Gireesh K., 1984-; Vizán, Pedro; Stanton, Lawrence W.; Beato, Miguel; Di Croce, Luciano; Marti-Renom, Marc A. (American Society for Microbiology, 2015)
    Discovering and classifying long noncoding RNAs (lncRNAs) across all mammalian tissues and cell lines remains a major challenge. Previously, mouse lncRNAs were identified using transcriptome sequencing (RNA-seq) data from ...
  • Vizán, Pedro; Di Croce, Luciano; Aranda Aragón, Sergio (Frontiers Media, 2021)
    Adenosylhomocysteinase (AHCY) is a unique enzyme and one of the most conserved proteins in living organisms. AHCY catalyzes the reversible break of S-adenosylhomocysteine (SAH), the by-product and a potent inhibitor of ...
  • Jain, Payal, 1986-; Ballaré, Cecilia Julia; Blanco, Enrique; Vizán, Pedro; Di Croce, Luciano (eLife, 2020)
    The Polycomb-like protein PHF19/PCL3 associates with PRC2 and mediates its recruitment to chromatin in embryonic stem cells. PHF19 is also overexpressed in many cancers. However, neither PHF19 targets nor misregulated ...
  • García Montolío, Marc, 1991-; Ballaré, Cecilia Julia; Blanco, Enrique; Gutiérrez, Arantxa; Aranda Aragón, Sergio; Gómez, Antonio; Kok, Chung H.; Yeung, David T.; Hughes, Timothy P.; Vizán, Pedro; Di Croce, Luciano (Frontiers Media, 2021)
    Polycomb group (PcG) of proteins are a group of highly conserved epigenetic regulators involved in many biological functions, such as embryonic development, cell proliferation, and adult stem cell determination. PHD finger ...
  • Vizán, Pedro; Beringer, Malte; Ballaré, Cecilia Julia; Di Croce, Luciano (Wiley-Blackwell, 2015)
    The Polycomb group (PcG) of proteins form chromatin-binding complexes with histone-modifying activity. The two main PcG repressive complexes studied (PRC1 and PRC2) are generally associated with chromatin in its repressed ...
  • Vizán, Pedro; Gutiérrez, Arantxa; Espejo, Isabel; García Montolio, Marc; Lange, Martin; Carretero, Ana; Lafzi, Atefeh; Andrés Aguayo, Luisa de; Blanco, Enrique; Thambyrajah, Roshana; Graf, T. (Thomas); Heyn, Holger; Bigas Salvans, Anna; Di Croce, Luciano (American Association for the Advancement of Science (AAAS), 2020)
    Adult hematopoietic stem cells (HSCs) are rare multipotent cells in bone marrow that are responsible for generating all blood cell types. HSCs are a heterogeneous group of cells with high plasticity, in part, conferred by ...