Browsing by Author "Vives Usano, Marta, 1990-"

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  • Comparison of smoking-related DNA methylation between newborns from prenatal exposure and adults from personal smoking
    Sikdar, Sinjini; Vives Usano, Marta, 1990-; Bustamante Pineda, Mariona; London, Stephanie J. (Future Medicine, 2019)
    Aim: Cigarette smoking influences DNA methylation genome wide, in newborns from pregnancy exposure and in adults from personal smoking. Whether a unique methylation signature exists for in utero exposure in newborns is ...
  • Early life tobacco exposure and children's telomere length: The HELIX project
    Osorio Yáñez, Citlalli; Clemente Batalha Pardal, Diana, 1990-; Maitre, Léa; Vives Usano, Marta, 1990-; Bustamante Pineda, Mariona; Martínez, David; Casas Sanahuja, Maribel; Urquiza, José M.; Tamayo-Uria, Ibon; Sunyer Deu, Jordi; Vrijheid, Martine (Elsevier, 2020)
    Telomere length and mitochondrial DNA content are considered biomarkers of cellular aging, oxidative stress, and inflammation, but there is almost no information on their association with tobacco smoke exposure in fetal ...
  • Human Early Life Exposome (HELIX) study: a European population-based exposome cohort
    Maitre, Léa; De Bont, Jeroen, 1989-; Casas Sanahuja, Maribel; Robinson, Oliver; Basagaña Flores, Xavier; Borràs, Eva; Bustamante Pineda, Mariona; de Castro, Montserrat; Donaire González, David; Estivill, Xavier, 1955-; Fossati, Serena; González, Juan Ramón; Hernández-Ferrer, Carles; Júlvez Calvo, Jordi; Manzano Salgado, Cyntia Beatriz, 1987-; Sabidó Aguadé, Eduard, 1981-; Sunyer Deu, Jordi; Tamayo-Uria, Ibon; Urquiza, José M.; van Gent, Diana; Vives Usano, Marta, 1990-; Warembourg, Charline; Nieuwenhuijsen, Mark J.; Vrijheid, Martine (BMJ Publishing Group, 2018)
    PURPOSE: Essential to exposome research is the collection of data on many environmental exposures from different domains in the same subjects. The aim of the Human Early Life Exposome (HELIX) study was to measure and ...
  • Identification of autosomal cis expression quantitative trait methylation (cis eQTMs) in children's blood
    Ruiz-Arenas, Carlos; Hernandez-Ferrer, Carles, 1987-; Vives Usano, Marta, 1990-; Marí, Sergi; Casas Sanahuja, Maribel; Vafeiadi, Marina, 1983-; Vrijheid, Martine; González Ruiz, Juan Ramón; Bustamante Pineda, Mariona (eLife Sciences Publications, 2022)
    Background: The identification of expression quantitative trait methylation (eQTMs), defined as associations between DNA methylation levels and gene expression, might help the biological interpretation of epigenome-wide ...
  • In utero and childhood exposure to tobacco smoke and multi-layer molecular signatures in children
    Vives Usano, Marta, 1990-; Hernández-Ferrer, Carles; Maitre, Léa; Ruiz Arenas, Carlos, 1990-; Borràs, Eva; Casas Sanahuja, Maribel; Estivill, Xavier, 1955-; González, Juan Ramón; Sabidó Aguadé, Eduard, 1981-; Vrijheid, Martine; Bustamante Pineda, Mariona (BioMed Central, 2020)
    Background: The adverse health effects of early life exposure to tobacco smoking have been widely reported. In spite of this, the underlying molecular mechanisms of in utero and postnatal exposure to tobacco smoke are only ...
  • Maternal haemoglobin levels in pregnancy and child DNA methylation: a study in the pregnancy and childhood epigenetics consortium
    Ronkainen, Justiina; Vives Usano, Marta, 1990-; Guxens Junyent, Mònica; Vrijheid, Martine; Bustamante Pineda, Mariona; Sebert, Sylvain (Taylor & Francis, 2022)
    Altered maternal haemoglobin levels during pregnancy are associated with pre-clinical and clinical conditions affecting the fetus. Evidence from animal models suggests that these associations may be partially explained by ...
  • Meta-analysis of epigenome-wide association studies in newborns and children show widespread sex differences in blood DNA methylation
    Solomon, Olivia; González, Juan Ramón; Llambrich, Maria; Vives Usano, Marta, 1990-; Maitre, Léa; Foraster Pulido, Maria, 1984-; Kogevinas, Manolis; Bustamante Pineda, Mariona; Holland, Nina (Elsevier, 2022)
    Background: Among children, sex-specific differences in disease prevalence, age of onset, and susceptibility have been observed in health conditions including asthma, immune response, metabolic health, some pediatric and ...
  • Multi-omics signatures of the human early life exposome
    Maitre, Léa; Bustamante Pineda, Mariona; Hernández Ferrer, Carles; Vives Usano, Marta, 1990-; Ruiz-Arenas, Carlos; Pelegrí-Sisó, Dolors; Casas Sanahuja, Maribel; Sunyer Deu, Jordi; Nieuwenhuijsen, Mark J.; Urquiza, José M.; Borràs, Eva; Sabidó Aguadé, Eduard, 1981-; Estivill, Xavier, 1955-; González, Juan Ramón; Vrijheid, Martine (Nature Research, 2022)
    Environmental exposures during early life play a critical role in life-course health, yet the molecular phenotypes underlying environmental effects on health are poorly understood. In the Human Early Life Exposome (HELIX) ...
  • Placental DNA methylation signatures of maternal smoking during pregnancy and potential impacts on fetal growth
    Everson, Todd M.; Vives Usano, Marta, 1990-; Sunyer Deu, Jordi; Bustamante Pineda, Mariona (Nature Research, 2021)
    Maternal smoking during pregnancy (MSDP) contributes to poor birth outcomes, in part through disrupted placental functions, which may be reflected in the placental epigenome. Here we present a meta-analysis of the associations ...
  • The early-life exposome and epigenetic age acceleration in children
    Prado Bert, Paula de; Ruiz Arenas, Carlos, 1990-; Vives Usano, Marta, 1990-; Dadvand, Payam; González, Juan Ramón; Maitre, Léa; Nieuwenhuijsen, Mark J.; Pelegrí, Dolors; Sunyer Deu, Jordi; Vrijheid, Martine; Bustamante Pineda, Mariona (Elsevier, 2021)
    The early-life exposome influences future health and accelerated biological aging has been proposed as one of the underlying biological mechanisms. We investigated the association between more than 100 exposures assessed ...
  • Variability of multi-omics profiles in a population-based child cohort
    Gallego-Paüls, Marta; Hernández-Ferrer, Carles; Bustamante Pineda, Mariona; Basagaña Flores, Xavier; Barrera Gómez, Jose; Vives Usano, Marta, 1990-; Ruiz Arenas, Carlos, 1990-; Casas Sanahuja, Maribel; Borràs, Eva; Sabidó Aguadé, Eduard, 1981-; Estivill, Xavier, 1955-; Urquiza, José M.; González, Juan Ramón; Vrijheid, Martine; Maitre, Léa (BioMed Central, 2021)
    Background: Multiple omics technologies are increasingly applied to detect early, subtle molecular responses to environmental stressors for future disease risk prevention. However, there is an urgent need for further ...