Browsing by Author "Visser, Pieter Jelle"

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  • Dementia prevalence and incidence in a federation of European Electronic Health Record databases: The European Medical Informatics Framework resource
    Perera, Gayan; Pedersen, Lars; Ansel, David; Alexander, Myriam; Arrighi, H. Michael; Avillach, Paul; Foskett, Nadia; Gini, Rosa; Gordon, Mark F.; Gungabissoona, Usha; Mayer, Miguel Ángel, 1960-; Novak, Gerald; Rijnbeek, Peter; Trifirò, Gianluca; van der Lei, Johan; Visser, Pieter Jelle; Stewart, Robert (Elsevier, 2018)
    INTRODUCTION: The European Medical Information Framework consortium has assembled electronic health record (EHR) databases for dementia research. We calculated dementia prevalence and incidence in 25 million persons from ...
  • Genetic, vascular and amyloid components of cerebral blood flow in a preclinical population
    Padrela, Beatriz E.; Lorenzini, Luigi; Collij, Lyduine E.; Vállez García, David; Coomans, Emma; Ingala, Silvia; Tomassen, Jori; Deckers, Quinten; Shekari, Mahnaz; de Geus, Eco; van de Giessen, Elsmarieke; Ten Kate, Mara; Visser, Pieter Jelle; Barkhof, Frederik; Petr, Jan; den Braber, Anouk; Mutsaerts, Henk (SAGE Publications, 2023)
    Aging-related cognitive decline can be accelerated by a combination of genetic factors, cardiovascular and cerebrovascular dysfunction, and amyloid-β burden. Whereas cerebral blood flow (CBF) has been studied as a potential ...
  • Gray matter network properties show distinct associations with CSF p-tau 181 levels and amyloid status in individuals without dementia
    Lorenzini, Luigi; Ingala, Silvia; Wottschel, Viktor; Wink, Alle Meije; Mutsaerts, Henk; Haller, Sven; Blennow, Kaj; O'Brien, John T.; Frisoni, Giovanni B.; Chételat, Gael; Payoux, Pierre; Martínez Lage, Pablo; Waldman, Adam; Wardlaw, Joanna; Ritchie, Craig; Gispert López, Juan Domingo; Visser, Pieter Jelle; Scheltens, Philip; Barkhof, Frederik; Tijms, Betty M. (Elsevier, 2022)
    Gray matter networks are altered with amyloid accumulation in the earliest stage of AD, and are associated with decline throughout the AD spectrum. It remains unclear to what extent gray matter network abnormalities are ...
  • Harmonization of brain PET images in multi-center PET studies using Hoffman phantom scan
    Shekari, Mahnaz; Verwer, Eline E.; Yaqub, Maqsood; Daamen, Marcel; Buckley, Christopher, 1948-; Frisoni, Giovanni B.; Visser, Pieter Jelle; Farrar, Gill; Barkhof, Frederik; Gispert López, Juan Domingo; Boellaard, Ronald; AMYPAD Consortium (Springer, 2023)
    Background: Image harmonization has been proposed to minimize heterogeneity in brain PET scans acquired in multi-center studies. However, standard validated methods and software tools are lacking. Here, we assessed the ...
  • Plasma levels of soluble TREM2 and neurofilament light chain in TREM2 rare variant carriers
    Ashton, Nicholas J.; Suárez-Calvet, Marc; Heslegrave, Amanda; Hye, Abdul; Razquin, Cristina; Pastor, Pau; Sanchez-Valle, Raquel; Molinuevo, José Luis; Visser, Pieter Jelle; Blennow, Kaj; Hodges, Angela K.; Zetterberg, Henrik (BioMed Central, 2019)
    Background: Results from recent clinical studies suggest that cerebrospinal fluid (CSF) biomarkers that are indicative of Alzheimer's disease (AD) can be replicated in blood, e.g. amyloid-beta peptides (Aβ42 and Aβ40) and ...
  • Regional amyloid accumulation predicts memory decline in initially cognitively unimpaired individuals
    Collij, Lyduine E.; Mastenbroek, Sophie E.; Salvadó, Gemma; Wink, Alle Meije; Visser, Pieter Jelle; Barkhof, Frederik; van Berckel, Bart N. M.; Lopes Alves, Isadora (Elsevier, 2021)
    Introduction: The value of quantitative longitudinal and regional amyloid beta (Aβ) measurements in predicting cognitive decline in initially cognitively unimpaired (CU) individuals remains to be determined. Methods: We ...
  • Spatial-temporal patterns of β-amyloid accumulation: a subtype and stage inference model analysis
    Collij, Lyduine E.; Salvadó, Gemma; Wottschel, Viktor; Mastenbroek, Sophie E.; Schoenmakers, Pierre; Heeman, Fiona; Aksman, Leon; Wink, Alle Meije; Berckel, Bart N.M.; van de Flier, Wiesje M.; Scheltens, Philip; Visser, Pieter Jelle; Barkhof, Frederik; Haller, Sven; Gispert López, Juan Domingo; Lopes Alves, Isadora; Alzheimer’s Disease Neuroimaging Initiative; ALFA Study (Lippincott Williams & Wilkins, 2022)
    Background and objectives: β-amyloid (Aβ) staging models assume a single spatial-temporal progression of amyloid accumulation. We assessed evidence for Aβ accumulation subtypes by applying the data-driven Subtype and Stage ...
  • Vascular and metabolic risk factor differences prior to dementia diagnosis: a multidatabase case-control study using European electronic health records
    Perera, Gayan; Rijnbeek, Peter; Alexander, Myriam; Ansel, David; Avillach, Paul; Duarte Salles, Talita, 1985-; Gordon, Mark F.; Lapi, Francesco; Mayer, Miguel Ángel, 1960-; Pasqua, Alessandro; Pedersen, Lars; van der Lei, Johan; Visser, Pieter Jelle; Stewart, Robert (BMJ Publishing Group, 2020)
    Objective: The objective of the study is to compare body mass index (BMI), systolic/diastolic blood pressure (SBP/DBP) and serum total cholesterol levels between dementia cases and controls at multiple time intervals prior ...

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