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Browsing by Author "Villanueva Cañas, José Luis, 1984-"

Browsing by Author "Villanueva Cañas, José Luis, 1984-"

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  • Vartia, Salla; Villanueva Cañas, José Luis, 1984-; Finarelli, John; Farrell, Edward D.; Collins, Patrick C.; Hughes, Graham M.; Carlsson, Jeanette E. L.; Gauthier, David T.; McGinnity, Philip; Cross, Thomas F.; FitzGerald, Richard D.; Mirimin, Luca; Crispie, Fiona; Cotter, Paul D.; Carlsson, Jens (Royal Society Publishing, 2016)
    This study examines the potential of next-generation sequencing based 'genotyping-by-sequencing' (GBS) of microsatellite loci for rapid and cost-effective genotyping in large-scale population genetic studies. The recovery ...
  • La Greca, Alejandro; Bellora Pereyra, Nicolás; Le Dily, François; Jara, Rodrigo; Nacht, A. Silvina; Quilez Oliete, Javier; Villanueva Cañas, José Luis, 1984-; Vidal Barba, Enric; Merino, Gabriela; Fresno, Cristóbal; Reischle, Inti Tarifa; Vallejo, Griselda; Vicent, Guillermo Pablo; Fernández, Elmer; Beato, Miguel; Saragüeta, Patricia (eLife Sciences Publications, 2022)
    Estrogen (E2) and Progesterone (Pg), via their specific receptors (ERalpha and PR), are major determinants in the development and progression of endometrial carcinomas, However, their precise mechanism of action and the ...
  • Hernández-Fernández, Javier; Pinzón Velasco, Andrés Mauricio; López Barrera Ellie Anne; Rodríguez Becerra, María Del Pilar; Villanueva Cañas, José Luis, 1984-; Albà Soler, Mar; Mariño Ramírez, Leonardo (Corte Madera, CA : PeerJ Inc., 2021)
    The aim of this study was to generate and analyze the atlas of the loggerhead turtle blood transcriptome by RNA-seq, as well as identify and characterize thioredoxin (Tnxs) and peroxiredoxin (Prdxs) antioxidant enzymes of ...
  • Villanueva Cañas, José Luis, 1984-; Horvath, Vivien; Aguilera, Laura; González, Josefa (Oxford University Press, 2019)
    Although transposable elements are an important source of regulatory variation, their genome-wide contribution to the transcriptional regulation of stress-response genes has not been studied yet. Stress is a major aspect ...
  • Villanueva Cañas, José Luis, 1984-; Fernández Fuentes, Narcís; Saul, Dominik; Kosinsky, Robyn Laura; Teyssier, Catherine; Rogalska, Malgorzata; Pegenaute Pérez, Ferran; Oliva Miguel, Baldomero; Notredame, Cedric; Beato, Miguel; Sharma, Priyanka (Elsevier, 2024)
    Peptidyl arginine deiminases (PADIs) catalyze protein citrullination, a post-translational conversion of arginine to citrulline. The most widely expressed member of this family, PADI2, regulates cellular processes that ...
  • Pickup, Katherine E.; Pardow, Felicitas; Carbonell-Caballero, Jose; Lioutas, Antonio, 1980-; Villanueva Cañas, José Luis, 1984-; Wright, Roni H.G.; Beato, Miguel (MDPI, 2019)
    The growth of cancer cells as oncospheres in three-dimensional (3D) culture provides a robust cell model for understanding cancer progression, as well as for early drug discovery and validation. We have previously described ...
  • Abascal, Federico; Corvelo, André; Cruz, Fernando; Villanueva Cañas, José Luis, 1984-; Vlasova, Anna; Marcet Houben, Marina; Prieto Barja, Pablo, 1986-; Quilez Oliete, Javier; Frias, Leonor; Ribeca, Paolo; Capella Gutiérrez, Salvador Jesús, 1985-; Câmara Ferreira, Francisco; Lowy Gallego, Ernesto; Cozzuto, Luca; Erb, Ionas; Rodríguez Ales, José Luis; Ruiz Orera, Jorge, 1988-; Reverter, Ferran; Derdak, Sophia; Blanc, Julie; Gut, Marta; Lorente-Galdós, Belén, 1981-; Gut, Ivo Glynne; Guigó Serra, Roderic; Gabaldón Estevan, Juan Antonio, 1973-; Godoy, José A. (BioMed Central, 2016)
    Background: Genomic studies of endangered species provide insights into their evolution and demographic history, reveal patterns of genomic erosion that might limit their viability, and offer tools for their effective ...
  • Faherty, Sheena L.; Villanueva Cañas, José Luis, 1984-; Klopfer, Peter H.; Albà Soler, Mar; Yoder, Anne D. (Oxford University Press, 2016)
    Hibernation is a complex physiological response that some mammalian species employ to evade energetic demands. Previous work in mammalian hibernators suggests that hibernation is activated not by a set of genes unique to ...
  • Le Dily, François; Vidal, Enrique; Cuartero, Yasmina; Quilez Oliete, Javier; Nacht, A. Silvina; Vicent, Guillermo Pablo; Carbonell-Caballero, Jose; Sharma, Priyanka; Villanueva Cañas, José Luis, 1984-; Ferrari, Roberto; De Llobet, Lara Isabel; Verde, Gaetano; Wright, Roni H.G.; Beato, Miguel (Cold Spring Harbor Laboratory Press (CSHL Press), 2019)
    In breast cancer cells, some topologically associating domains (TADs) behave as hormonal gene regulation units, within which gene transcription is coordinately regulated in response to steroid hormones. Here we further ...
  • Villanueva Cañas, José Luis, 1984-; Laurie, Steven, 1973-; Albà Soler, Mar (Oxford University Press, 2013)
    Large-scale evolutionary studies often require the automated construction of alignments of a large number of homologous gene families. The majority of eukaryotic genes can produce different transcripts due to alternative ...
  • Villanueva Cañas, José Luis, 1984-; Ruiz Orera, Jorge, 1988-; Agea, M. Isabel; Gallo, María, 1989-; Andreu Martínez, David; Albà Soler, Mar (Oxford University Press, 2017)
    The birth of genes that encode new protein sequences is a major source of evolutionary innovation. However, we still understand relatively little about how these genes come into being and which functions they are selected ...
  • Rech, Gabriel E.; Bogaerts Márquez, María, 1991-; Barrón, Maite G.; Merenciano, Miriam; Villanueva Cañas, José Luis, 1984-; Horváth, Vivien, 1990-; Fiston Lavier, Anna Sophie; Luyten, Isabelle; Venkataram, Sandeep; Quesneville, Hadi; Petrov, Dmitri A.; González, Josefa (Public Library of Science (PLoS), 2019)
    Most of the current knowledge on the genetic basis of adaptive evolution is based on the analysis of single nucleotide polymorphisms (SNPs). Despite increasing evidence for their causal role, the contribution of structural ...
  • Ruiz-Orera, Jorge; Verdaguer-Grau, Pol; Villanueva Cañas, José Luis, 1984-; Messeguer, Xavier; Albà Soler, Mar (Springer, 2018)
    Accumulating evidence indicates that some protein-coding genes have originated de novo from previously non-coding genomic sequences. However, the processes underlying de novo gene birth are still enigmatic. In particular, ...
  • Blevins, William Robert, 1987-; Ruiz Orera, Jorge, 1988-; Messeguer, Xavier; Blasco Moreno, Bernat, 1986-; Villanueva Cañas, José Luis, 1984-; Espinar, Lorena; Díez Antón, Juana, 1962-; Carey, Lucas, 1980-; Albà Soler, Mar (Nature Research, 2021)
    De novo gene origination has been recently established as an important mechanism for the formation of new genes. In organisms with a large genome, intergenic and intronic regions provide plenty of raw material for new ...

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