Browsing by Author "Villanueva Belmonte, Cristina"

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  • Jain, Pooja; Vineis, Paolo; Liquet, Benoît; Vlaanderen, Jelle; Bodinier, Barbara; van Veldhoven, Karin; Kogevinas, Manolis; Athersuch, Toby J.; Font-Ribera, Laia; Villanueva Belmonte, Cristina; Vermeulen, Roel; Chadeau-Hyam, Marc (BMJ Publishing Group, 2018)
    Epidemiological studies provide evidence that environmental exposures may affect health through complex mixtures. Formal investigation of the effect of exposure mixtures is usually achieved by modelling interactions, which ...
  • Villanueva Belmonte, Cristina; Gracia Lavedan, Esther; Castaño Vinyals, Gemma; Espinosa Díaz, Ana; Espejo Herrera, Nadia Carminia, 1983-; Nieuwenhuijsen, Mark J.; Kogevinas, Manolis (Environmental health perspectives, 2016)
    BACKGROUND: Evidence on the association between colorectal cancer and exposure to disinfection by-products in drinking water is inconsistent. OBJECTIVES: We assessed long-term exposure to trihalomethanes (THMs), the most ...
  • Espejo Herrera, Nadia Carminia, 1983-; Gràcia Lavedan, Esther; Castaño Vinyals, Gemma; Basagaña Flores, Xavier; Nieuwenhuijsen, Mark J.; Kogevinas, Manolis; Villanueva Belmonte, Cristina (Wiley, 2016)
    Ingested nitrate leads to the endogenous synthesis of N-nitroso compounds (NOCs), animal carcinogens with limited human evidence. We aimed to evaluate the risk of colorectal cancer (CRC) associated with nitrate exposure ...
  • Cserbik, Dora; Casas Sanahuja, Maribel; Flores, Cintia; Paraian, Alexandra; Haug, Line Småstuen; Rivas, Ioar; Bustamante Pineda, Mariona; Dadvand, Payam; Sunyer Deu, Jordi; Vrijheid, Martine; Villanueva Belmonte, Cristina (Nature Research, 2023)
  • Salas, Lucas A.; Bustamante Pineda, Mariona; González Ruiz, Juan Ramón; Gracia Lavedan, Esther; Moreno, Víctor; Kogevinas, Manolis; Villanueva Belmonte, Cristina (Taylor & Francis, 2015)
    Trihalomethanes (THM) are undesired disinfection byproducts (DBPs) formed during water treatment. Mice exposed to DBPs showed global DNA hypomethylation and c-myc and c-jun gene-specific hypomethylation, while evidence of ...
  • Pedersen, Marie; Mendez, Michelle A.; Espinosa Díaz, Ana; Villanueva Belmonte, Cristina; Gracia Lavedan, Esther; Sunyer Deu, Jordi; Nieuwenhuijsen, Mark J.; Cirach, Marta; Agramunt, Silvia; Kogevinas, Manolis (National Institute of Environmental Health Sciences, 2015)
    BACKGROUND: Bulky DNA adducts reflect genotoxic exposures, have been associated with lower birth weight, and may predict cancer risk. OBJECTIVE: We selected factors known or hypothesized to affect in utero adduct formation ...
  • Font Ribera, Laia (Universitat Pompeu Fabra, 2010-11-29)
    ANTECEDENTS: La natació té beneficis per la salut, però l’assistència a piscines comporta l’exposició a subproductes de la cloració (SPC). Els banyistes podrien tenir cert risc de patir efectes respiratoris, com l’asma, ...
  • Font-Ribera, Laia; Barreiro Portela, Esther; Gracia Lavedan, Esther; Arjona, Lourdes; De Bont, Jeroen, 1989-; Tarès, Lluïsa; Vineis, Paolo; Kogevinas, Manolis; Villanueva Belmonte, Cristina (Elsevier, 2019)
    BACKGROUND: Swimming in pools is a healthy activity that entails exposure to disinfection by-products (DBPs), some of which are irritant and genotoxic. OBJECTIVES: We evaluated exposure to DBPs during swimming in a chlorinated ...
  • Villanueva Belmonte, Cristina; Gracia Lavedan, Esther; Ibarluzea, Jesús; Marina, Loreto Santa; Ballester Díez, Ferran; Llop, Sabrina; Tardón, Adonina; Fernandez, Mariana F.; Freire, Carmen; Goñi, Fernando; Basagaña Flores, Xavier; Kogevinas, Manolis; Grimalt Obrador, Joan; Sunyer Deu, Jordi (National Institute of Environmental Health Sciences (NIEHS), 2011)
    Background: Evidence associating exposure to water disinfection by-products with reduced birth weight and altered duration of gestation remains inconclusive. Objective: We assessed exposure to trihalomethanes (THMs) during ...
  • Salas, Lucas A.; Font Ribera, Laia; Bustamante Pineda, Mariona; Sumoy Van Dyck, Lauro; Grimalt Obrador, Joan; Bonnin, Sarah; Aguilar Morón, María Asunción; Mattlin, Heidi; Hummel, Manuela; Ferrer Del Alamo, Ana; Kogevinas, Manolis; Villanueva Belmonte, Cristina (Elsevier, 2017)
    Exposure to disinfection by-products (DBP) such as trihalomethanes (THM) in swimming pools has been linked to adverse health effects in humans, but their biological mechanisms are unclear. We evaluated short-term changes ...
  • Espejo Herrera, Nadia Carminia, 1983-; Gràcia Lavedan, Esther; Font Ribera, Laia; Castaño Vinyals, Gemma; Kogevinas, Manolis; Villanueva Belmonte, Cristina (Environmental Health Perspectives, 2016)
    BACKGROUND: Ingested nitrate leads to endogenous formation of N-nitroso compounds that are breast carcinogens in animals, but human evidence is limited. OBJECTIVE: We evaluated ingested nitrate as a risk factor for breast ...
  • Redondo-Hasselerharm, Paula E.; Cserbik, Dora; Flores, Cintia; Farré, Maria José; Sanchís, Josep; Alcolea, Jose A.; Planas, Carles; Caixach, Josep; Villanueva Belmonte, Cristina (Nature Research, 2022)
    Background: knowledge about human exposure and health effects associated with non-routinely monitored disinfection by-products (DBPs) in drinking water is sparse. Objective: to provide insights to estimate exposure to ...
  • Donat-Vargas, Carolina; Kogevinas, Manolis; Benavente, Yolanda; Costas, Laura; Campo, Elias; Castaño Vinyals, Gemma; Fernandez-Tardon, Guillermo; Llorca, Javier; Gómez-Acebo, Inés; Aragonés, Núria; Pollan, Marina; Casabonne, Delphine; Villanueva Belmonte, Cristina (Nature Research, 2023)
    Background: Chronic lymphocytic leukemia (CLL) etiology is poorly understood, and carcinogenic chemicals in drinking and recreational water are candidates. Objective: To evaluate the association between drinking-water ...
  • Salas, Lucas A.; Villanueva Belmonte, Cristina; Tajuddin, Salman Muhammad; Amaral, André F.S.; Fernández, Agustín F.; Moore, Lee E.; Carrato, Alfredo; Tardón, Adonina; Serra, Consol; García Closas, Reina; Basagaña Flores, Xavier; Rothman, Nathaniel; Silverman, Debra T.; Cantor, Kenneth P; Kogevinas, Manolis; Real, Francisco X.; Fraga, Mario F.; Malats i Riera, Núria (Taylor & Francis (Routledge), 2014)
    DNA methylation changes contribute to bladder carcinogenesis. Trihalomethanes (THM), a class of disinfection by-products, are associated with increased urothelial bladder cancer (UBC) risk. THM exposure in animal models ...
  • Maitre, Léa; Villanueva Belmonte, Cristina; Lewis, Matthew R.; Ibarluzea, Jesús; Santa Marina, Loreto; Vrijheid, Martine; Sunyer Deu, Jordi; Coen, Muireann; Toledano, Mireille B. (BioMed Central, 2016)
    BACKGROUND: Maternal metabolism during pregnancy is a major determinant of the intra-uterine environment and fetal outcomes. Herein, we characterize the maternal urinary metabolome throughout pregnancy to identify maternal ...
  • Espejo Herrera, Nadia Carminia, 1983- (Universitat Pompeu Fabra, 2015-11-13)
    Ingested nitrate is a precursor of N-nitroso compounds that are carcinogens in animals, with limited evidence in humans. The main objective of this thesis was to evaluate whether the exposure to nitrate through drinking ...
  • Sanchís, Josep; Redondo-Hasselerharm, Paula E.; Villanueva Belmonte, Cristina; Farré, Maria José (Elsevier, 2022)
    The generation of disinfection by-products during water chlorination is a major concern in water treatment, given the potential health risks that these substances may pose. In particular, nitrogen-containing DBPs are ...
  • Cantor, Kenneth P; Villanueva Belmonte, Cristina; Silverman, Debra T.; Figueroa, Jonine D.; Real, Francisco X.; García Closas, Montserrat; Malats i Riera, Núria; Chanock, Stephen J.; Yeager, Meredith; Tardón, Adonina; García Closas, Reina; Serra, Consol; Carrato, Alfredo; Castaño Vinyals, Gemma; Samanic, Claudine; Rothman, Nathaniel; Kogevinas, Manolis (National Institute of Environmental Health Sciences (NIEHS), 2010)
    Background: Bladder cancer has been linked with long-term exposure to disinfection by-products (DBPs) in drinking water.Objectives: In this study we investigated the combined influence of DBP exposure and polymorphisms in ...
  • Castaño Vinyals, Gemma; Cantor, Kenneth P; Villanueva Belmonte, Cristina; Tardón, Adonina; García Closas, Reina; Serra, Consol; Carrato, Alfredo; Malats i Riera, Núria; Rothman, Nathaniel; Silverman, Debra T.; Kogevinas, Manolis (BioMed Central, 2011)
    Background: Disinfection by-products in drinking water are chemical contaminants that have been associated with cancer and other adverse effects. Exposure occurs from consumption of tap water, inhalation and dermal absorption. ...
  • Gil-Solsona, Ruben; Nika, Maria-Christina; Bustamante Pineda, Mariona; Villanueva Belmonte, Cristina; Foraster Pulido, Maria, 1984-; Cosín-Tomás, Marta; Alygizakis, Nikiforos; Gómez-Roig, María Dolores; Llurba, Elisa; Sunyer Deu, Jordi; Thomaidis, Nikolaos S.; Dadvand, Payam; Gago-Ferrero, Pablo (American Chemical Society (ACS), 2021)
    Chemicals are part of our daily lives, and we are exposed to numerous chemicals through multiple pathways. Relevant scientific evidence contributing to the regulation of hazardous chemicals require a holistic approach to ...

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