Browsing by Author "Vieta, Eduard"

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  • A Pharmacovigilance study in first episode of psychosis: psychopharmacological interventions and safety profiles in the PEPs Project.
    Bioque, Miquel; Llerena, Adrián; Cabrera, Bibiana; Mezquida, Gisela; Lobo, Antonio; González-Pinto, Ana; Díaz-Caneja, Covadonga M.; Corripio, Iluminada; Aguilar, Eduardo J.; Bulbena Vilarrasa, Antonio; Castro-Fornieles, Josefina; Vieta, Eduard; Lafuente, Amàlia; Mas, Sergi; Parellada, Mara; Saiz-Ruiz, Jerónimo; Cuesta, Manuel J.; Bernardo, Miquel; PEPs Group (Oxford University Press, 2016)
    BACKGROUND: The characterization of the first episode of psychosis and how it should be treated are principal issues in actual research. Realistic, naturalistic studies are necessary to represent the entire population of ...
  • A study on the bioequivalence of lithium and valproate salivary and blood levels in the treatment of bipolar disorder
    Murru, Andrea; Torra, Mercè; Callari, Antonio; Pacchiarotti, Isabella; Romero, Sergio; Gonzalez de la Presa, Bernardino; Varo, Cristina; Goikolea, Jose M.; Pérez Solá, Victor; Vieta, Eduard; Colom, Francesc (Elsevier, 2017)
    Lithium (Li) and valproate (VPA) are used in the treatment of bipolar disorder (BD), with narrow therapeutic window requiring periodic control of serum levels. This prevents intoxication, lack of efficacy due to low serum ...
  • Behavioural biomarkers and mobile mental health: a new paradigm
    Hidalgo Mazzei, Diego; Young, Allan H.; Vieta, Eduard; Colom, Francesc (SpringerOpen, 2018)
    Over recent decades, the field of psychiatry has allocated a vast amount of resources and efforts to make available more accurate and objective methods to diagnose, assess and monitor treatment outcomes in psychiatric ...
  • Bipolar disorder and antibodies against the N-methyl-d-aspartate receptor: A gate to the involvement of autoimmunity in the pathophysiology of bipolar illness.
    León Caballero, Jordi; Pacchiarotti, Isabella; Murru, Andrea; Valentí, M.; Colom, Francesc; Benach, B.; Pérez Solá, Victor; Dalmau, Josep; Vieta, Eduard (Elsevier, 2015)
    The high prevalence of comorbidity between bipolar disorder (BD) and other medical conditions, including autoimmune diseases, supports the hypothesis of the nature of BD as a biological illness category. Hence, an immune ...
  • Cognition in recent suicide attempts: altered executive function
    Fernández-Sevillano, Jessica; Alberich, Susana; Zorrilla, Iñaki; González-Ortega, I.; López, María Purificación; Pérez Solá, Victor; Vieta, Eduard; González-Pinto, Ana; Saiz, Pilar A. (Frontiers, 2021)
    Background: Neuropsychological alterations can lead to inaccurate perception, interpretation, and response to environmental information, which could be a risk factor for suicide. Methods: Ninety-six subjects were recruited ...
  • Cognitive remediation interventions in schizoaffective disorder: a systematic review
    López-Fernández, Ester; Sole, Brisa; Jiménez, Esther; Salagre, Estela; Giménez, Anna; Murru, Andrea; Bonnín, Caterina del Mar; Amann, Benedikt Lorenz; Grande, Iria; Vieta, Eduard; Martínez-Aran, Anabel (Frontiers, 2018)
    ackground: Patients with schizoaffective disorder (SAD) suffer from cognitive impairment, which negatively influences their functionality. Cognitive remediation (CR) interventions have been shown to be effective in patients ...
  • Combining MRI and clinical data to detect high relapse risk after the first episode of psychosis
    Solanes, Aleix; Mezquida, Gisela; Janssen, Joost; Amoretti, Silvia; Lobo, Antonio; González-Pinto, Ana; Arango, Celso; Vieta, Eduard; Castro-Fornieles, Josefina; Bergé, Daniel; Albacete, Auria; Giné, Eloi; Parellada, Mara; Bernardo, Miquel; PEPs Group; Pomarol-Clotet, Edith; Radua, Joaquim (Nature Research, 2022)
    Detecting patients at high relapse risk after the first episode of psychosis (HRR-FEP) could help the clinician adjust the preventive treatment. To develop a tool to detect patients at HRR using their baseline clinical and ...
  • Economic impact of treatment-resistant depression: A retrospective observational study
    Pérez Solá, Victor; Roca, Miquel; Alonso Caballero, Jordi; Gabilondo Cuéllar, Andrea; Hernando, Teresa; Sicras Mainar, Antoni; Sicras Navarro, Aram; Herrera, Berta; Vieta, Eduard (Elsevier, 2021)
    Background: To determine the incidence of Treatment-Resistant Depression (TRD) in Spain and to estimate its economic burden, using real world data. Methods: A retrospective, observational-study was carried out using data ...
  • Effects of the COVID-19 pandemic and lockdown in Spain: comparison between community controls and patients with a psychiatric disorder
    Solé, Brisa; Verdolini, Norma; Amoretti, Silvia; Montejo, Laura; Rosa, Adriane R.; Hogg, Bridget; García-Rizo, Clemente; Mezquida, Gisela; Bernardo, Miquel; Martínez-Aran, Anabel; Vieta, Eduard; Torrent, Carla (Elsevier, 2021)
    Background: The aim of this study was to evaluate potential differences about the effects of the COVID-19 pandemic and lockdown between community controls (CC) and patients with a mental illness (MI) in a Spanish population ...
  • Epidemiology and costs of depressive disorder in Spain: the EPICO study
    Vieta, Eduard; Alonso Caballero, Jordi; Pérez Solá, Victor; Roca, Miquel; Hernando, Teresa; Sicras Navarro, Aram; Herrera, Berta; Gabilondo Cuéllar, Andrea (Elsevier, 2021)
    Depressive Disorders are the most common psychiatric diagnoses in the general population. To estimate the frequency, costs associated with Depressive Disorders in usual clinical practice, and in the whole Spanish population, ...
  • Evaluation of machine learning algorithms and structural features for optimal MRI-based diagnostic prediction in psychosis
    Salvador, Raymond; Radua, Joaquim; Canales-Rodrıguez, Erick J.; Solanes, Aleix; Sarró, Salvador; Goikolea, Jose M.; Valiente Gómez, Alicia; Monte, Gemma; Natividad, Marıa del Carmen; Guerrero-Pedraza, Amalia; Moro, Noemí; Fernandez-Corcuera, Paloma; Amann, Benedikt Lorenz; Maristany, Teresa; Vieta, Eduard; McKenna, Peter J.; Pomarol-Clotet, Edith (Public Library of Science (PLoS), 2017)
    A relatively large number of studies have investigated the power of structural magnetic resonance imaging (sMRI) data to discriminate patients with schizophrenia from healthy controls. However, very few of them have also ...
  • Exploration of cannabis use and polygenic risk scores on the psychotic symptom progression of a FEP cohort
    Segura, Àlex G.; Mané Santacana, Anna; Prohens, Llucia; Rodríguez, Natalia; Mezquida, Gisela; Cuesta, Manuel J.; Vieta, Eduard; Amoretti, Silvia; Lobo, Antonio; González-Pinto, Ana; Díaz-Caneja, Covadonga M.; Roldán Bejarano, Alexandra; Jiménez, Esther; Baeza, Immaculada; Legido, Teresa; Saiz-Ruiz, Jerónimo; Bernardo, Miquel; Mas, Sergi; PEPs Group (Elsevier, 2023)
    Cannabis use is highly prevalent in first-episode psychosis (FEP) and plays a critical role in its onset and prognosis, but the genetic underpinnings promoting both conditions are poorly understood. Current treatment ...
  • Eye movement desensitization and reprocessing therapy versus supportive therapy in affective relapse prevention in bipolar patients with a history of trauma: study protocol for a randomized controlled trial
    Moreno Alcázar, Ana; Radua, Joaquim; Landín-Romero, Ramon; Blanco, Laura; Madre, Mercè; Reinares, Maria; Comes, Mercè; Jiménez, Esther; Crespo, Jose Manuel; Vieta, Eduard; Pérez Solá, Victor; Novo Navarro, Maria Patricia; Doñate Font, Marta; Cortizo Vidal, Romina; Valiente Gómez, Alicia; Lupo, Walter; McKenna, Peter J.; Pomarol-Clotet, Edith; Amann, Benedikt Lorenz (BioMed Central, 2017)
    BACKGROUND: Up to 60% of patients with bipolar disorder (BD) have a history of traumatic events, which is associated with greater episode severity, higher risk of comorbidity and higher relapse rates. Trauma-focused treatment ...
  • Glucocorticoid receptors, brain-derived neurotrophic factor, serotonin and dopamine neurotransmission are associated with interferon-induced depression.
    Udina, M. ; Navinés, Ricard; Egmond, E.  ; Oriolo, Giovanni; Langohr, Klaus; Gimenez, Dolors; Valdés, M. ; Gómez-Gil, E. ; Grande, Iria; Gratacós Mayora, Mònica; Kapczinski, F.  ; Artigas, Francesc; Vieta, Eduard; Solà, Rosa; Martín Santos, Rocío (Oxford University Press, 2016)
    BACKGROUND: The role of inflammation in mood disorders has received increased attention. There is substantial evidence that cytokine therapies, such as interferon alpha (IFN-alpha), can induce depressive symptoms. Indeed, ...
  • Impact of previous tobacco use with or without cannabis on first psychotic experiences in patients with first-episode psychosis
    González-Blanco, Leticia; García-Portilla, María Paz; Gutiérrez, Miguel; Mezquida, Gisela; Cuesta, Manuel J.; Urbiola, Elena; Amoretti, Silvia; Barcones, Fe; González-Pinto, Ana; Pina-Camacho, Laura; Corripio, Iluminada; Vieta, Eduard; Baeza, Immaculada; Toll Privat, Alba; Sáiz, Pilar A.; Bobes, Julio; Bernardo, Miquel; PEPs Group (Elsevier, 2021)
    Objective: There is high prevalence of cigarette smoking in individuals with first-episode psychosis (FEP) prior to psychosis onset. The purpose of the study was to determine the impact of previous tobacco use with or ...
  • In memory of hagop akiskal
    Carta, Mauro G.; Colom, Francesc; Erfurth, Andreas; Fornaro, Michele; Grunze, Heinz; Hantouche, Elie; Nardi, Antonio E.; Preti, Antonio; Vieta, Eduard; Karam, Elie G. (Bentham Open, 2021)
  • Influence of clinical and neurocognitive factors in psychosocial functioning after a first episode non-affective psychosis: Differences between males and females
    Serra-Navarro, Maria; Amoretti, Silvia; Verdolini, Norma; Forte, María Florencia; Sánchez-Torres, Ana M.; Vieta, Eduard; Clougher, Derek; Lobo, Antonio; González-Pinto, Ana; Panadero, Rocío; Roldán, Alexandra; Carvalho, André F.; Serna, Elena de la; Toll Privat, Alba; Ramos Quiroga, Josep Antoni; Torrent, Carla; Cuesta, Manuel J.; Bernardo, Miquel; PEPs Group (Frontiers, 2022)
    Background: Deficits in psychosocial functioning are present in the early stages of psychosis. Several factors, such as premorbid adjustment, neurocognitive performance, and cognitive reserve (CR), potentially influence ...
  • La psiquiatría post-COVID-19
    Vieta, Eduard; Pérez Solá, Victor; Arango, Celso (Elsevier, 2020)
  • Metabolic polygenic risk scores effect on antipsychotic-induced metabolic dysregulation: a longitudinal study in a first episode psychosis cohort
    Segura, Àlex G.; Martínez-Pinteño, Albert; Gassó, Patricia; Rodríguez, Natalia; Bioque, Miquel; Cuesta, Manuel J.; González-Peñas, Javier; García-Rizo, Clemente; Lobo, Antonio; González-Pinto, Ana; García-Alcón, Alicia; Roldán, Alexandra; Vieta, Eduard; Castro-Fornieles, Josefina; Mané Santacana, Anna; Saiz-Ruiz, Jerónimo; Bernardo, Miquel; Mas, Sergi (Elsevier, 2022)
    Objective: metabolic syndrome is a health-threatening condition suffered by approximately one third of schizophrenia patients and largely attributed to antipsychotic medication. Previous evidence reports a common genetic ...
  • Obstetric complications and genetic risk for schizophrenia: differential role of antenatal and perinatal events in first episode psychosis
    Valli, Isabel; González Segura, Àlex; Verdolini, Norma; García-Rizo, Clemente; Berge Baquero, Daniel; Baeza, Immaculada; Cuesta, Manuel J.; Gonzalez-Pinto, Ana; Lobo, Antonio; Martinez-Aran, Anabel; Mezquida, Gisela; Pina-Camacho, Laura; Roldan Bejarano, Alexandra; Mas, Sergi; McGuire, Philip; Bernardo, Miquel; Vieta, Eduard; PEPs Group (Wiley, 2023)
    Background: Obstetric complications (OCs) are key contributors to psychosis risk. However, it is unclear whether they increase psychosis vulnerability independently of genetic risk, in interaction with it, or are a ...

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