Browsing by Author "Vélez de Mendizábal, Nieves"

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Dynamic cross-regulation of antigen-specific effector and regulatory T cell subpopulations and microglia in brain autoimmunity

Martínez Pasamar, Sara; Abad Adan, Elena; Moreno, Beatriz; Vélez de Mendizábal, Nieves; Martínez Forero, Ivan; García Ojalvo, Jordi; Villoslada, Pablo (BioMed Central, 2013)

Background: Multiple Sclerosis (MS) is considered a T-cell-mediated autoimmune disease with a prototypical oscillatory behavior, as evidenced by the presence of clinical relapses. Understanding the dynamics of immune cells ...
Modeling the effector - regulatory T cell cross-regulation reveals the intrinsic character of relapses in multiple sclerosis

Vélez de Mendizábal, Nieves; Carneiro, Jorge; Solé Vicente, Ricard, 1962-; Goñi, Joaquín; Bragard, Jean; Martínez Forero, Ivan; Martínez Pasamar, Sara; Sepulcre, Jorge; Torrealdea, Javier; Bagnato, Francesca; García Ojalvo, Jordi; Villoslada, Pablo (BioMed Central, 2011)

Background: The relapsing-remitting dynamics is a hallmark of autoimmune diseases such as Multiple Sclerosis (MS). Although current understanding of both cellular and molecular mechanisms involved in the pathogenesis of ...

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