Browsing by Author "Ule, Jernej"

Sort by: Order: Results:

  • Exon junction complex shapes the transcriptome by repressing recursive splicing
    Blazquez, Lorea; Emmett, Warren; Faraway, Rupert; Pineda, Jose Mario Bello; Bajew, Simon, 1994-; Gohr, André; Haberman, Nejc; Sibley, Christopher R.; Bradley, Robert K.; Irimia Martínez, Manuel; Ule, Jernej (Elsevier, 2018)
    Recursive splicing (RS) starts by defining an "RS-exon," which is then spliced to the preceding exon, thus creating a recursive 5' splice site (RS-5ss). Previous studies focused on cryptic RS-exons, and now we find that ...
  • Nuclear matrix protein Matrin3 regulates alternative splicing and forms overlapping regulatory networks with PTB
    Coelho, Miguel B.; Attig, Jan; Bellora Pereyra, Nicolás; König, Julian; Hallegger, Martina; Kayikci, Melis; Eyras Jiménez, Eduardo; Ule, Jernej; Smith, Christopher, W. J. (EMBO Press, 2015)
    Matrin3 is an RNA- and DNA-binding nuclear matrix protein found to be associated with neural and muscular degenerative diseases. A number of possible functions of Matrin3 have been suggested, but no widespread role in RNA ...
  • ORC1 binds to cis-transcribed RNAs for efficient activation of replication origins
    Mas, Aina Maria; Goñi, Enrique; Ruiz de Los Mozos, Igor; Arcas Mantas, Aida; Statello, Luisa; González, Jovanna; Blázquez, Lorea; Lee, Wei Ting Chelsea; Gupta, Dipika; Sejas, Álvaro; Hoshina, Shoko; Armaos, Alexandros, 1989-; Tartaglia, Gian Gaetano; Waga, Shou; Ule, Jernej; Rothenberg, Eli; Gómez, María; Huarte, Maite (Nature Research, 2023)
    Cells must coordinate the activation of thousands of replication origins dispersed throughout their genome. Active transcription is known to favor the formation of mammalian origins, although the role that RNA plays in ...
  • The alternative splicing program of differentiated smooth muscle cells involves concerted non-productive splicing of post-transcriptional regulators
    Llorian, Miriam; Gooding, Clare; Bellora Pereyra, Nicolás; Hallegger, Martina; Buckroyd, Adrian; Wang, Xiao; Rajgor, Dipen; Kayikci, Melis; Feltham, Jack; Ule, Jernej; Eyras Jiménez, Eduardo; Smith, Christopher, W. J. (Oxford University Press, 2016)
    Alternative splicing (AS) is a key component of gene expression programs that drive cellular differentiation. Smooth muscle cells (SMCs) are important in the function of a number of physiological systems; however, investigation ...

Search DSpace

Browse

My Account

In collaboration with Compliant to Partaking