Browsing by Author "Tyler-Smith, Chris"

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  • Aboriginal Australian mitochondrial genome variation – an increased understanding of population antiquity and diversity
    Nagle, Nano; van Oven, Mannis; Wilcox, Stephen; van Holst Pellekaan, Sheila; Tyler-Smith, Chris; Xue, Yali; Ballantyne, Kaye N.; Wilcox, Leah; Papac, Luka; Cooke, Karen; van Oorschot, Roland A. H.; McAllister, Peter; Williams, Lesley; Manfred, Kayser; Mitchell, R. John; Genographic Consortium; Bertranpetit, Jaume, 1952-; Comas, David, 1969-; Haber, Marc, 1980-; Martínez Cruz, Begoña; Melé Messeguer, Marta, 1982- (Nature Publishing Group, 2017)
    Aboriginal Australians represent one of the oldest continuous cultures outside Africa, with evidence indicating that their ancestors arrived in the ancient landmass of Sahul (present-day New Guinea and Australia) ~55 ...
  • Afghanistan's ethnic groups share a y-chromosomal heritage structured by historical events
    Haber, Marc, 1980-; Platt, Daniel E.; Ashrafian Bonab, Maziar; Youhanna, Sonia; Soria Hernanz, David F; Martínez Cruz, Begoña; Douaihy, Bouchra; Ghassibe-Sabbaghm, Michella; Rafatpanah, Hoshang; Ghanbari, Mohsen; Whale, John; Balanovsky, Oleg; Wells, R. Spencer; Comas, David, 1969-; Tyler-Smith, Chris; Zalloua, Pierre A.; Genographic Consortium (Public Library of Science (PLoS), 2012)
    Afghanistan has held a strategic position throughout history. It has been inhabited since the Paleolithic and later became a crossroad for expanding civilizations and empires. Afghanistan's location, history, and diverse ...
  • Genes regulated by vitamin D in bone cells are positively selected in East Asians
    Arciero, Elena; Biagini, Simone Andrea, 1983-; Chen, Yuan; Xue, Yali; Luiselli, Donata; Tyler-Smith, Chris; Pagani, Luca; Ayub, Qasim (Public Library of Science (PLoS), 2015)
    Vitamin D and folate are activated and degraded by sunlight, respectively, and the physiological processes they control are likely to have been targets of selection as humans expanded from Africa into Eurasia. We investigated ...
  • Genetic evidence for an origin of the Armenians from Bronze Age mixing of multiple populations
    Haber, Marc, 1980-; Mezzavilla, Massimo; Xue, Yali; Comas, David, 1969-; Gasparini, Paolo; Zalloua, Pierre A.; Tyler-Smith, Chris (Nature Publishing Group, 2015)
    The Armenians are a culturally isolated population who historically inhabited a region in the Near East bounded by the Mediterranean and Black seas and the Caucasus, but remain under-represented in genetic studies and have ...
  • Genome-wide diversity in the levant reveals recent structuring by culture
    Haber, Marc, 1980-; Gauguier, Dominique; Youhanna, Sonia; Patterson, Nick; Moorjani, Priya; Botigué, Laura R.; Platt, Daniel E.; Matisoo Smith, Elizabeth; Soria Hernanz, David F; Wells, R. Spencer; Bertranpetit, Jaume, 1952-; Tyler-Smith, Chris; Comas, David, 1969-; Zalloua, Pierre A. (Public Library of Science (PLoS), 2013)
    The Levant is a region in the Near East with an impressive record of continuous human existence and major cultural developments since the Paleolithic period. Genetic and archeological studies present solid evidence placing ...
  • Human genomic regions with exceptionally high levels of population differentiation identified from 911 whole-genome sequences
    Colonna, Vincenza; Ayub, Qasim; Cheng, Yuan; Pagani, Luca; Luisi, Pierre, 1985-; Pybus Oliveras, Marc, 1985-; Garrison, Erik; Xue, Yali; Tyler-Smith, Chris; The 1000 Genomes Project Consortium (BioMed Central, 2014)
    Background: Population differentiation has proved to be effective for identifying loci under geographically localized positive selection, and has the potential to identify loci subject to balancing selection. We have ...
  • Positive selection in admixed populations from Ethiopia
    Walsh Capdevila, Sandra, 1991-; Pagani, Luca; Xue, Yali; Laayouni, Hafid, 1968-; Tyler-Smith, Chris; Bertranpetit, Jaume, 1952- (BioMed Central, 2020)
    Background: In the process of adaptation of humans to their environment, positive or adaptive selection has played a main role. Positive selection has, however, been under-studied in African populations, despite their ...
  • The dawn of human matrilineal diversity
    Behar, Doron M.; Villems, Richard; Soodyall, Himla; Blue-Smith, Jason; Pereira, Luisa; Metspalu, Ene; Scozzari, Rosaria; Makkan, Heeran; Tzur, Shay; Comas, David, 1969-; Bertranpetit, Jaume, 1952-; Quintana Murci, Lluis; Tyler-Smith, Chris; Wells, R. Spencer; Rosset, Saharon; Genographic Consortium (University of Chicago Press, 2008)
    The quest to explain demographic history during the early part of human evolution has been limited because of the scarce paleoanthropological record from the Middle Stone Age. To shed light on the structure of the mitochondrial ...
  • The GenoChip: a new tool for genetic anthropology
    Elhaik, Eran; Greenspan, Elliott; Staats, Sean; Krahn, Thomas; Tyler-Smith, Chris; Xue, Yali; Tofanelli, Sergio; Francalacci, Paolo; Cucca, Francesco; Pagani, Luca; Jin, Li; Li, Hui; Schurr, Theodore G.; Greenspan, Bennett; Wells, R. Spencer; Genographic Consortium; Bertranpetit, Jaume, 1952-; Comas, David, 1969-; Martínez Cruz, Begoña (Oxford University Press, 2013)
    The Genographic Project is an international effort aimed at charting human migratory history. The project is nonprofit and nonmedical, and, through its Legacy Fund, supports locally led efforts to preserve indigenous and ...
  • The Simons Genome Diversity Project: 300 genomes from 142 diverse populations
    Mallick, Swapan; Li, Heng; Lipson, Mark; Mathieson, Ian; Gymrek, Melissa; Racimo, Fernando; Zhao, Mengyao; Chennagiri, Niru; Nordenfelt, Susanne; Tandom, Arti; Skoglund, Pontus; Lazaridis, Iosif; Sankararaman, Sriram; Fu, Qiaomei; Rohland, Nadin; Renaud, Gabriel; Erlich, Yaniv; Willems, Thomas; Gallo, Carla; Spence, Jeffrey P.; Song, Yun S.; Poletti, Giovanni; Balloux, François; van Driem, George; de Knijff, Peter; Gallego Romero, Irene; Jha, Aashish R.; Behar, Doron M.; Bravi, Claudio M.; Capelli, Cristian; Hervig, Tor; Moreno Estrada, Andrés; Posukh, Olga L.; Balanovska, Elena; Balanovsky, Oleg; Karachanak-Yankova, Sena; Sahakyan, Hovhannes; Toncheva, Draga; Yepiskoposyan, Levon; Tyler-Smith, Chris; Xue, Yali; Abdullah, M. Syafiq; Ruiz-Linares, Andres; Beall, Cynthia M.; Di Rienzo, Anna; Jeong, Choongwon; Starikovskaya, Elena B.; Metspalu, Ene; Parik, Jüri; Villems, Richard; Henn, Brenna M.; Hodoglugil, Ugur; Mahley, Robert; Sajantila, Antii; Stamatoyannopoulos, George; Wee, Joseph T.S.; Khusainova, Rita; Khusnutdinova, Elza; Litvinov, Sergey; Ayodo, George; Comas, David, 1969-; Hammer, Michael; Kivisild, Toomas; Klitz, William; Winkler, Cheryl; Labuda, Damian; Bamshad, Michael; Jorde, Lynn B.; Tishkoff, Sarah A.; Watkins, W. Scott; Metspalu, Mait; Dryomov, Stanislav; Sukernik, Rem; Singh, Lalji; Thangaraj, Kumarasamy; Pääbo, Svante; Kelso, Janet; Patterson, Nick; Reich, David (Nature Publishing Group, 2016)
    Here we report the Simons Genome Diversity Project data set: high quality genomes from 300 individuals from 142 diverse populations. These genomes include at least 5.8 million base pairs that are not present in the human ...
  • Using ancestry-informative markers to identify fine structure across 15 populations of European origin
    Huckins, Laura M.; Boraska, Vesna; Franklin, Christopher S.; Floyd, James A. B.; Southam, Lorraine; GCAN; WTCCC3; Sullivan, Patrick F.; Bulik, Cynthia M.; Collier, David A.; Tyler-Smith, Chris; Zeggini, Eleftheria; Tachmazidou, Ioanna (Springer, 2014)
    The Wellcome Trust Case Control Consortium 3 anorexia nervosa genome-wide association scan includes 2907 cases from 15 different populations of European origin genotyped on the Illumina 670K chip. We compared methods for ...
  • Y-chromosomal sequences of diverse Indian populations and the ancestry of the Andamanese
    Mondal, Mayukh, 1989-; Bergström, Anders; Xue, Yali; Calafell i Majó, Francesc; Laayouni, Hafid, 1968-; Casals López, Ferran; Majumder, Partha P.; Tyler-Smith, Chris; Bertranpetit, Jaume, 1952- (Springer, 2017)
    We present 42 new Y-chromosomal sequences from diverse Indian tribal and non-tribal populations, including the Jarawa and Onge from the Andaman Islands, which are analysed within a calibrated Y-chromosomal phylogeny ...
  • Y-Chromosome and mtDNA genetics reveal significant contrasts in affinities of modern Middle Eastern populations with European and African populations
    Badro, Danielle A.; Douaihy, Bouchra; Haber, Marc, 1980-; Youhanna, Sonia; Salloum, Angélique; Ghassibe-Sabbaghm, Michella; Johnsrud, Brian; Khazen, Georges; Matisoo Smith, Elizabeth; Soria Hernanz, David F.; Wells, R. Spencer; Tyler-Smith, Chris; Platt, Daniel E.; Zalloua, Pierre A.; Genographic Consortium (Public Library of Science (PLoS), 2013)
    The Middle East was a funnel of human expansion out of Africa, a staging area for the Neolithic Agricultural Revolution, and the home to some of the earliest world empires. Post LGM expansions into the region and subsequent ...

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