Browsing by Author "Torres-Diz, Manuel"

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  • A convergent malignant phenotype in B-cell acute lymphoblastic leukemia involving the splicing factor SRRM1
    Closa, Adrià; Reixachs-Solé, Marina; Fuentes-Fayos, Antonio C.; Hayer, Katharina E.; Melero, Juan L.; Adriaanse, Fabienne R.S.; Bos, Romy S.; Torres-Diz, Manuel; Hunger, Stephen P.; Roberts, Kathryn G.; Mullighan, Charles G.; Stam, Ronald W.; Thomas-Tikhonenko, Andrei; Castaño, Justo P.; Luque, Raul M.; Eyras Jiménez, Eduardo (Oxford University Press, 2022)
    A significant proportion of infant B-cell acute lymphoblastic leukemia (B-ALL) patients remains with a dismal prognosis due to yet undetermined mechanisms. We performed a comprehensive multicohort analysis of gene expression, ...
  • MYC activation impairs cell-intrinsic IFNγ signaling and confers resistance to anti-PD1/PD-L1 therapy in lung cancer
    Alburquerque-Bejar, Juan J.; Navajas-Chocarro, Pablo; Saigi, Maria; Ferrero-Andrés, Ana; Morillas, Juan M.; Vilarrubi, Andrea; Gómez, Antonio; Mate, José Luís; Muñoz-Mármol, Ana M.; Romero, Octavio A.; Blecua, Pedro; Davalos, Veronica; Esteller, Manel; Pros, Eva; Llabata, Paula; Torres-Diz, Manuel; Esteve-Codina, Anna; Sánchez Céspedes, Montse (Elsevier, 2023)
    Elucidating the adaptive mechanisms that prevent host immune response in cancer will help predict efficacy of anti-programmed death-1 (PD1)/L1 therapies. Here, we study the cell-intrinsic response of lung cancer (LC) to ...

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