Browsing by Author "Torre, Beatriz G. de la"

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  • Blanco, Esther; Cubillos, Carolina; Moreno, Noelia; Bárcena, Juan; Torre, Beatriz G. de la; Andreu Martínez, David; Sobrino, Francisco (Taylor & Francis Health (Routledge), 2013)
    Synthetic peptides incorporating protective B- and T-cell epitopes are candidates for new safer foot-and-mouth disease (FMD) vaccines. We have reported that dendrimeric peptides including four copies of a B-cell epitope ...
  • Oeste, Clara L.; Díez Dacal, Beatriz; Bray, Francesca; García de Lacoba, Mario; Torre, Beatriz G. de la; Andreu Martínez, David; Ruiz Sánchez, Antonio J; Pérez Inestrosa, Ezequiel; García Domínguez, Carlota A; Rojas, José M; Pérez Sala, Dolores (Public Library of Science (PLoS), 2011)
    Ras proteins are crucial players in differentiation and oncogenesis and constitute important drug targets. The localization and activity of Ras proteins are highly dependent on posttranslational modifications at their ...
  • Abengózar, María Ángeles; Fernández Reyes, María; Salazar, Vivian A.; Torrent Burgas, Marc; Torre, Beatriz G. de la; Andreu Martínez, David; Boix, Ester; Rivas, Luis (American Chemical Society (ACS), 2022)
    The recruitment of eosinophils into Leishmania lesions is frequently associated with a favorable evolution. A feasible effector for this process is eosinophil cationic protein (ECP, RNase 3), one of the main human eosinophil ...
  • Soria, Ivana; Quattrocchi, Valeria; Langellotti, Cecilia; Pérez-Filgueira, Mariano; Pega, J.; Gnazzo, V.; Romera, S.; Schammas, J.; Bucafusco, D.; Di Giacomo, S.; Torre, Beatriz G. de la; Andreu Martínez, David; Sobrino, Francisco; Blanco, Esther; Zamorano, Patricia (Hindawi, 2018)
    Synthetic peptides mimicking protective B- and T-cell epitopes are good candidates for safer, more effective FMD vaccines. Nevertheless, previous studies of immunization with linear peptides showed that they failed to ...
  • Rodrigues, Margarida; Santos, Andrea; Torre, Beatriz G. de la; Rádis Baptista, Gandhi; Andreu Martínez, David; Santos, Nuno C. (Elsevier, 2012)
    A novel class of cell-penetrating, nucleolar-targeting peptides (NrTPs), was recently developed from the rattlesnake venom toxin crotamine. Based on the intrinsic fluorescence of tyrosine or tryptophan residues, the partition ...
  • García Mayoral, María Flor; Moussaoui, Mohammed; Torre, Beatriz G. de la; Andreu Martínez, David; Boix, Ester; Nogués, Victòria M.; Rico, Manuel; Laurents, Douglas V.; Bruix, Marta (Elsevier, 2010)
    Eosinophil cationic protein (ECP) is a highly stable, cytotoxic ribonuclease with the ability to enter and disrupt membranes that participates in innate immune defense against parasites but also kills human cells. We have ...
  • González Magaldi, Mónica; Vázquez Calvo, Ángela; Torre, Beatriz G. de la; Valle, Javier; Andreu Martínez, David; Sobrino, Francisco (Public Library of Science (PLoS), 2015)
    Nonstructural protein 3A is involved in relevant functions in foot-and-mouth disease virus (FMDV) replication. FMDV 3A can form homodimers and preservation of the two hydrophobic α-helices (α1 and α2) that stabilize the ...
  • Solanas, Concepción; Torre, Beatriz G. de la; Fernández Reyes, María; Santiveri, Clara M.; Jiménez, M. Ángeles; Rivas, Luis; Jiménez, Ana I.; Andreu Martínez, David; Cativiela, Carlos (American Chemical Society (ACS), 2010)
    A series of gramicidin S (GS) analogues have been synthesized where the Phe (i + 1) and Pro (i + 2) residues of the beta-turn have been swapped while the respective chiralities (D-, L-) at each position are preserved, and ...
  • Solanas, Concepción; Torre, Beatriz G. de la; Fernández Reyes, María; Santiveri, Clara M.; Jiménez, M. Ángeles; Rivas, Luis; Jiménez, Ana I.; Andreu Martínez, David; Cativiela, Carlos (American Chemical Society (ACS), 2009)
    Analogues of the cationic antimicrobial peptide gramicidin S (GS), cyclo(Val-Orn-Leu-D-Phe-Pro)2, with d-Phe residues replaced by different (restricted mobility, mostly) surrogates have been synthesized and used in SAR ...

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