Visualitza per autoria "Torre, Beatriz G. de la"

Ordena per: Ordre: Resultats:

  • B epitope multiplicity and B/T epitope orientation influence immunogenicity of foot-and-mouth disease peptide vaccines
    Blanco, Esther; Cubillos, Carolina; Moreno, Noelia; Bárcena, Juan; Torre, Beatriz G. de la; Andreu Martínez, David; Sobrino, Francisco (Taylor & Francis Health (Routledge), 2013)
    Synthetic peptides incorporating protective B- and T-cell epitopes are candidates for new safer foot-and-mouth disease (FMD) vaccines. We have reported that dendrimeric peptides including four copies of a B-cell epitope ...
  • The C-terminus of H-ras as a target for the covalent binding of reactive compounds modulating Ras-dependent pathways
    Oeste, Clara L; Díez Dacal, Beatriz; Bray, Francesca; García de Lacoba, Mario; Torre, Beatriz G. de la; Andreu Martínez, David; Ruiz Sánchez, Antonio J; Pérez Inestrosa, Ezequiel; García Domínguez, Carlota A; Rojas, José M; Pérez Sala, Dolores (Public Library of Science (PLoS), 2011)
    Ras proteins are crucial players in differentiation and oncogenesis and constitute important drug targets. The localization and activity of Ras proteins are highly dependent on posttranslational modifications at their ...
  • Essential role of enzymatic activity in the leishmanicidal mechanism of the eosinophil cationic protein (RNase 3)
    Abengózar, María Ángeles; Fernández Reyes, María; Salazar, Vivian A.; Torrent Burgas, Marc; Torre, Beatriz G. de la; Andreu Martínez, David; Boix, Ester; Rivas, Luis (American Chemical Society (ACS), 2022)
    The recruitment of eosinophils into Leishmania lesions is frequently associated with a favorable evolution. A feasible effector for this process is eosinophil cationic protein (ECP, RNase 3), one of the main human eosinophil ...
  • Immune response and partial protection against heterologous foot-and-mouth disease virus induced by dendrimer peptides in cattle
    Soria, Ivana; Quattrocchi, Valeria; Langellotti, Cecilia; Pérez-Filgueira, Mariano; Pega, J.; Gnazzo, V.; Romera, S.; Schammas, J.; Bucafusco, D.; Di Giacomo, S.; Torre, Beatriz G. de la; Andreu Martínez, David; Sobrino, Francisco; Blanco, Esther; Zamorano, Patricia (Hindawi, 2018)
    Synthetic peptides mimicking protective B- and T-cell epitopes are good candidates for safer, more effective FMD vaccines. Nevertheless, previous studies of immunization with linear peptides showed that they failed to ...
  • Molecular characterization of the interaction of crotamine-derived nucleolar targeting peptides with lipid membranes
    Rodrigues, Margarida; Santos, Andrea; Torre, Beatriz G. de la; Rádis Baptista, Gandhi; Andreu Martínez, David; Santos, Nuno C. (Elsevier, 2012)
    A novel class of cell-penetrating, nucleolar-targeting peptides (NrTPs), was recently developed from the rattlesnake venom toxin crotamine. Based on the intrinsic fluorescence of tyrosine or tryptophan residues, the partition ...
  • NMR structural determinants of eosinophil cationic protein binding to membrane and heparin mimetics
    García Mayoral, María Flor; Moussaoui, Mohammed; Torre, Beatriz G. de la; Andreu Martínez, David; Boix, Ester; Nogués, Victòria M; Rico, Manuel; Laurents, Douglas V.; Bruix, Marta (Elsevier, 2010)
    Eosinophil cationic protein (ECP) is a highly stable, cytotoxic ribonuclease with the ability to enter and disrupt membranes that participates in innate immune defense against parasites but also kills human cells. We have ...
  • Peptides interfering 3A protein dimerization decrease FMDV multiplication
    González Magaldi, Mónica; Vázquez Calvo, Ángela; Torre, Beatriz G. de la; Valle, Javier; Andreu Martínez, David; Sobrino, Francisco (Public Library of Science (PLoS), 2015)
    Nonstructural protein 3A is involved in relevant functions in foot-and-mouth disease virus (FMDV) replication. FMDV 3A can form homodimers and preservation of the two hydrophobic α-helices (α1 and α2) that stabilize the ...
  • Sequence inversion and phenylalanine surrogates at the beta-turn enhance the antibiotic activity of gramicidin S
    Solanas, Concepción; Torre, Beatriz G. de la; Fernández Reyes, María; Santiveri, Clara M.; Jiménez, M. Ángeles; Rivas, Luis; Jiménez, Ana I.; Andreu Martínez, David; Cativiela, Carlos (American Chemical Society (ACS), 2010)
    A series of gramicidin S (GS) analogues have been synthesized where the Phe (i + 1) and Pro (i + 2) residues of the beta-turn have been swapped while the respective chiralities (D-, L-) at each position are preserved, and ...
  • Therapeutic Index of Gramicidin S is Strongly Modulated by d-Phenylalanine Analogues at the β-Turn
    Solanas, Concepción; Torre, Beatriz G. de la; Fernández Reyes, María; Santiveri, Clara M.; Jiménez, M. Ángeles; Rivas, Luis; Jiménez, Ana I.; Andreu Martínez, David; Cativiela, Carlos (American Chemical Society (ACS), 2009)
    Analogues of the cationic antimicrobial peptide gramicidin S (GS), cyclo(Val-Orn-Leu-D-Phe-Pro)2, with d-Phe residues replaced by different (restricted mobility, mostly) surrogates have been synthesized and used in SAR ...

Cerca

Visualitza

El meu compte

Amb col·laboració de Complim Participem