Browsing by Author "Tierling, Sascha"

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  • Bisulfite profiling of the MGMT promoter and comparison with routine testing in glioblastoma diagnostics
    Tierling, Sascha; Jürgens-Wemheuer, Wiebke M.; Leismann, Alea; Becker-Kettern, Julia; Scherer, Michael; Wrede, Arne; Breuskin, David; Urbschat, Steffi; Sippi, Christoph; Oertel, Joachim; Schulz-Schaeffer, Walter J.; Walter, Jörn (BioMed Central, 2022)
    Background: Promoter methylation of the DNA repair gene O6-methylguanine-DNA methyltransferase (MGMT) is an acknowledged predictive epigenetic marker in glioblastoma multiforme and anaplastic astrocytoma. Patients with ...