Browsing by Author "Swoger, Jim"

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  • Mayer, Jürgen, 1977-; Robert Moreno, Alexandre; Sharpe, James; Swoger, Jim (Nature Research, 2018)
    Light sheet fluorescence microscopy (LSFM) is rapidly becoming an essential technology for mesoscopic imaging of samples such as embryos and adult mouse organs. However, LSFM can suffer from optical artifacts for which ...
  • Trussart, Marie, 1985-; Yus, Eva; Martínez, Sira; Baù, Davide; Tahara, Yuhei O.; Pengo, Thomas; Widjaja, Michael; Kretschmer, Simon; Swoger, Jim; Djordjevic, Steven P.; Turnbull, Lynne; Whitchurch, Cynthia B.; Miyata, Makoto; Martí Renom, Marc A.; Lluch-Senar, Maria 1982-; Serrano Pubull, Luis, 1982- (Nature Publishing Group, 2017)
    DNA-binding proteins are central regulators of chromosome organization; however, in genome-reduced bacteria their diversity is largely diminished. Whether the chromosomes of such bacteria adopt defined three-dimensional ...
  • Olarte, Omar E.; Licea-Rodriguez, Jacob; Palero, Jonathan A.; Gualda, Emilio J.; Artigas, David; Mayer, Jürgen, 1977-; Swoger, Jim; Sharpe, James; Rocha-Mendoza, Israel; Rangel-Rojo, Raul; Loza-Alvarez, Pablo (Optical Society of America (OSA), 2012)
    We present the implementation of a combined digital scanned light-sheet microscope (DSLM) able to work in the linear and nonlinear regimes under either Gaussian or Bessel beam excitation schemes. A complete characterization ...
  • Abe, Jun; Ozga, Aleksandra J.; Swoger, Jim; Sharpe, James; Ripoll, Jorge; Stein, Jens V. (Elsevier, 2016)
    Reactive lymph nodes (LNs) are sites where pMHC-loaded dendritic cells (DCs) interact with rare cognate T cells, leading to their clonal expansion. While DC interactions with T cell subsets critically shape the ensuing ...
  • Mayer, Jürgen, 1977- (Universitat Pompeu Fabra, 2015-11-10)
    This thesis covers a number of technical developments, to improve mesoscopic imaging and analysis, with a focus on quantitative imaging. The main topic is attenuation in light sheet fluorescence microscopies (LSFM). ...
  • Martínez Abadías, Neus; Mateu-Estivill, Roger; Sastre-Tomas, Jaume; Motch Perrine, Susan; Yoon, Melissa; Robert Moreno, Alexandre; Swoger, Jim; Russo, Lucia; Kawasaki, Kazuhiko (eLife, 2018)
    The earliest developmental origins of dysmorphologies are poorly understood in many congenital diseases. They often remain elusive because the first signs of genetic misregulation may initiate as subtle changes in gene ...
  • Mayer, Jürgen, 1977-; Swoger, Jim; Ozga, Aleksandra J.; Stein, Jens V.; Sharpe, James (Hindawi, 2012)
    Deep tissue imaging has become state of the art in biology, but now the problem is to quantify spatial information in a global, organ-wide context. Although access to the raw data is no longer a limitation, the computational ...