Browsing by Author "Sumoy Van Dyck, Lauro"

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  • Cyclic AMP signaling restricts activation and promotes maturation and antioxidant defenses in astrocytes
    Paco, Sonia; Hummel, Manuela; Plá, Virginia; Sumoy Van Dyck, Lauro; Aguado, Fernando (BioMed Central, 2016)
    BACKGROUND: cAMP signaling produces dramatic changes in astrocyte morphology and physiology. However, its involvement in phenotype acquisition and the transcriptionally mediated mechanisms of action are largely unknown. ...
  • Gene expression changes in blood RNA after swimming in a chlorinated pool
    Salas, Lucas A.; Font Ribera, Laia; Bustamante Pineda, Mariona; Sumoy Van Dyck, Lauro; Grimalt Obrador, Joan; Bonnin, Sarah; Aguilar Morón, María Asunción; Mattlin, Heidi; Hummel, Manuela; Ferrer Del Alamo, Ana; Kogevinas, Manolis; Villanueva Belmonte, Cristina (Elsevier, 2017)
    Exposure to disinfection by-products (DBP) such as trihalomethanes (THM) in swimming pools has been linked to adverse health effects in humans, but their biological mechanisms are unclear. We evaluated short-term changes ...
  • Genomic profiling in advanced stage non-small-cell lung cancer patients with platinum-based chemotherapy identifies germline variants with prognostic value in SMYD2
    Galván-Femenía, Iván; Guindo Martínez, Marta; Duran Jordà, Xavier, 1974-; Calabuig-Fariñas, Sílvia; Mercader Bigas, Josep Maria; Ramirez, Jose Luis; Rosell, Rafael; Torrents, David; Carreras, Anna; Kohno, Takashi; Jantus-Lewintre, Eloisa; Camps, Carlos; Perucho, Manuel; Sumoy Van Dyck, Lauro; Yokota, Jun; Cid Ibeas, Rafael de (Elsevier, 2018)
    Objective: The aim of the study was to investigate the relationship between germline variations as a prognosis biomarker in patients with advanced Non-Small-Cell-Lung-Cancer (NSCLC) subjected to first-line platinum-based ...
  • Hypothalamus transcriptome profile suggests an anorexia-cachexia syndrome in the anx/anx mouse model
    Mercader Bigas, Josep Maria; Lozano, Juan José; Sumoy Van Dyck, Lauro; Dierssen, Mara; Visa, Joana; Gratacós Mayora, Mònica; Estivill, Xavier, 1955- (American Physiological Society, 2008)
    The anx/anx mouse displays poor appetite and lean appearance and is considered a good model for the study of anorexia nervosa. To identify new genes involved in feeding behavior and body weight regulation we performed an ...
  • Microarray and deep sequencing cross-platform analysis of the mirRNome and isomiR variation in response to epidermal growth factor
    Llorens, Franc; Hummel, Manuela; Pantano Rubiño, Lorena, 1982-; Pastor, Xavier; Vivancos Prellezo, Ana; Castillo Andreo, Esther; Mattlin, Heidi; Ferrer Admetlla, Anna; Ingham, Matthew; Noguera, Marc; Kofler, Robert; Dohm, Juliane C.; Pluvinet, Raquel; Bayés, Mònica; Himmelbauer, Heinz; del Río, José Antonio; Martí, Eulàlia; Sumoy Van Dyck, Lauro (BioMed Central, 2013)
    Background: Epidermal Growth Factor (EGF) plays an important function in the regulation of cell growth, proliferation, and differentiation by binding to its receptor (EGFR) and providing cancer cells with increased survival ...
  • Multiple platform assessment of the EGF dependent transcriptome by microarray and deep tag sequencing analysis
    Llorens, Franc; Hummel, Manuela; Pastor Ruiz, Javier; Ferrer Salvador, Anna; Pluvinet, Raquel; Vivancos Prellezo, Ana; Castillo Andreo, Esther; Iraola Guzmán, Susana; Mosquera Miguel, Ana; González-Roca, Eva; Lozano, Juan José; Ingham, Matthew; Dohm, Juliane C.; Noguera, Marc; Kofler, Robert; Río, Jose Antonio del; Bayés, Mònica; Himmelbauer, Heinz; Sumoy Van Dyck, Lauro (BioMed Central, 2011)
    Background: Epidermal Growth Factor (EGF) is a key regulatory growth factor activating many processes relevant to normal development and disease, affecting cell proliferation and survival. Here we use a combined approach ...
  • Pathway oriented stroid hormone-dependent transcriptome analysis. Establishment of a custom cDNA microarray to study hormone signaling in breast cancer
    Miñana Gómez, Belén (Universitat Pompeu Fabra, 2011-04-12)
    Para avanzar en el entendimiento de las vías de señalización moleculares involucradas en la progresión de cáncer tumoral, se construyo una plataforma personalizada de cDNAs, la cual contiene genes de vías de señalización ...

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