Lujan, Agustin Leonardo; Foresti, Ombretta; Sugden, Conor; Brouwers, Nathalie; Farre, Alex Mateo; Vignoli, Alessio; Azamian, Mahshid; Turner, Alicia; Wojnacki, José; Malhotra, Vivek
(eLife, 2023)
We show that TANGO2 in mammalian cells localizes predominantly to mitochondria and partially at mitochondria sites juxtaposed to lipid droplets (LDs) and the endoplasmic reticulum. HepG2 cells and fibroblasts of patients ...