Browsing by Author "Stracker, Travis"

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  • Núñez Ollé, Marc, 1984-; Stracker, Travis; Gil Gómez, Gabriel (Impact Journals, 2018)
  • Stevanović, Irena, 1980- (Universitat Pompeu Fabra, 2013-12-04)
    We have identified PrimPol, a yet uncharacterized protein that can act in vitro as a low processivity polymerase able to bypasses thymine dimers in DNA. PrimPol localizes to both the nucleus and mitochondria. In order to ...
  • Núñez Ollé, Marc, 1984-; Jung, Carole; Terré, Berta; Balsiger, Norman A.; Plata, Cristina; Roset i Huguet, Ramon; Pardo Pastor, Carlos; Garrido, Marta; Rojas, Santiago; Alameda Quitllet, Francisco; Lloreta Trull, Josep, 1958-; Martín Caballero, Juan; Flores, Juana M.; Stracker, Travis; Valverde, M. A. (Miguel Ángel), 1963-; Muñoz López, Francisco José, 1964-; Gil Gómez, Gabriel (Impact Journals, 2017)
    Cyclin O (encoded by CCNO) is a member of the cyclin family with regulatory functions in ciliogenesis and apoptosis. Homozygous CCNO mutations have been identified in human patients with Reduced Generation of Multiple ...
  • Terré, Berta; Piergiovanni, Gabriele; Segura-Bayona, Sandra; Gil Gómez, Gabriel; Youssef, Sameh A.; Attolini, Camille Stephan-Otto; Wilsch-Bräuninger, Michaela; Jung, Carole; Rojas Mendoza, Ana Maria; Marjanovi c, Marko; Knobel, Philip A.; Palenzuela, Lluís; López-Rovira, Teresa; Forrow, Stephen; Huttner, Wieland B.; Valverde, M. A. (Miguel Ángel), 1963-; de Bruin, Alain; Costanzo, Vincenzo; Stracker, Travis (EMBO Press, 2016)
    The generation of multiciliated cells (MCCs) is required for the proper function of many tissues, including the respiratory tract, brain, and germline. Defects in MCC development have been demonstrated to cause a subclass ...
  • Picchioni, Daria; Antolin-Fontes, Albert; Camacho, Noelia; Schmitz, Claus; Pons-Pons, Alba; Rodríguez-Escribà, Marta; Machallekidou, Antoni; Güler, Merve Nur; Siatra, Panagiota; Carretero-Junquera, Maria; Serrano, Alba; Hovde, Stacy L.; Knobel, Philip A.; Novoa, Eva Maria; Solà-Vilarrubias, Maria; Kaguni, Laurie S.; Stracker, Travis; Ribas de Pouplana, Lluís (Elsevier, 2019)
    The aminoacylation of tRNAs by aminoacyl-tRNA synthetases (ARSs) is a central reaction in biology. Multiple regulatory pathways use the aminoacylation status of cytosolic tRNAs to monitor and regulate metabolism. The ...
  • Navarro, Judith; Gozalbo-López, Beatriz; Méndez, Andrea C.; Dantzer, Françoise; Schreiber, Valérie; Martínez, Carlos; Arana, David M.; Farrés, Jordi; Revilla-Nuin, Beatriz; Bueno, María F.; Ampurdanés, Coral; Galindo-Campos, Miguel A.; Knobel, Philip A.; Segura-Bayona, Sandra; Martin-Caballero, Juan; Stracker, Travis; Aparicio, Pedro; Del Val, Margarita; Yelamos López, Jose (Nature Publishing Group, 2017)
    The maintenance of T-cell homeostasis must be tightly regulated. Here, we have identified a coordinated role of Poly(ADP-ribose) polymerase-1 (PARP-1) and PARP-2 in maintaining T-lymphocyte number and function. Mice bearing ...
  • Rein, Katrin, 1983- (Universitat Pompeu Fabra, 2015-03-23)
    The maintenance of genome stability is crucial for homeostasis, development and suppression of diverse pathologies that include developmental disorders, premature aging and cancer. The DNA damage response coordinates the ...
  • Aivio, Suvi Marjaana, 1981- (Universitat Pompeu Fabra, 2014-10-10)
    Mitochondrial dysfunction arising from aberrant mitochondrial nucleic acid homeostasis has been associated with various pathologies. In this thesis, we aim to characterize a putative mitochondrial exonuclease, EXD2, and ...